FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034162787> ?p ?o ?g. }

• W2034162787 endingPage "3696" @default.
• W2034162787 startingPage "3687" @default.
• W2034162787 abstract "Oligosaccharides from human and bovine milk fat globule membranes were analyzed by LC-MS and LC-MS/MS. Global release of N-linked and O-linked oligosaccharides showed both to be highly sialylated, with bovine peak-lactating milk O-linked oligosaccharides presenting as mono- and disialylated core 1 oligosaccharides (Galβ1-3GalNAcol), while human milk had core type 2 oligosaccharides (Galβ1-3(GlcNAcβ1-6)GalNAcol) with sialylation on the C-3 branch. The C-6 branch of these structures was extended with branched and unbranched N-acetyllactosamine units terminating in blood group H and Lewis type epitopes. These epitopes were also presented on the reducing terminus of the human, but not the bovine, N-linked oligosaccharides. The O-linked structures were found to be attached to the high molecular mass mucins isolated by agarose-polyacrylamide composite gel electrophoresis, where MUC1 and MUC4 were present. Analysis of bovine colostrum showed that O-linked core 2 oligosaccharides are present at the early stage (3 days after birth) but are down-regulated as lactation develops. This data indicates that human milk may provide different innate immune protection against pathogens compared to bovine milk, as evidenced by the presence of Lewis b epitope, a target for the Helicobacter pylori bacteria, on human, but not bovine, milk fat globule membrane mucins. In addition, non-mucin-type O-linked fucosylated oligosaccharides were found (NeuAc-Gal-GlcNAc1-3Fuc-ol in bovine milk and Gal-GlcNAc1-3Fuc-ol in human milk). The O-linked fucose structure in human milk is the first to our knowledge to be found on high molecular mass mucin-type molecules." @default.
• W2034162787 created "2016-06-24" @default.
• W2034162787 creator A5020306466 @default.
• W2034162787 creator A5023684865 @default.
• W2034162787 creator A5029523842 @default.
• W2034162787 creator A5036445169 @default.
• W2034162787 creator A5043680660 @default.
• W2034162787 creator A5067372054 @default.
• W2034162787 date "2008-07-15" @default.
• W2034162787 modified "2023-10-16" @default.
• W2034162787 title "Glycoproteomics of Milk: Differences in Sugar Epitopes on Human and Bovine Milk Fat Globule Membranes" @default.
• W2034162787 cites W1838101286 @default.
• W2034162787 cites W1942573777 @default.
• W2034162787 cites W1967115518 @default.
• W2034162787 cites W1976555242 @default.
• W2034162787 cites W1979035951 @default.
• W2034162787 cites W1985484175 @default.
• W2034162787 cites W1991592905 @default.
• W2034162787 cites W1994241309 @default.
• W2034162787 cites W1995958771 @default.
• W2034162787 cites W1998305109 @default.
• W2034162787 cites W2001869838 @default.
• W2034162787 cites W2010487152 @default.
• W2034162787 cites W2023912458 @default.
• W2034162787 cites W2024837230 @default.
• W2034162787 cites W2028274716 @default.
• W2034162787 cites W2030214474 @default.
• W2034162787 cites W2042956754 @default.
• W2034162787 cites W2075197793 @default.
• W2034162787 cites W2075672935 @default.
• W2034162787 cites W2076603801 @default.
• W2034162787 cites W2081268598 @default.
• W2034162787 cites W2091016446 @default.
• W2034162787 cites W2092559728 @default.
• W2034162787 cites W2096469227 @default.
• W2034162787 cites W2150547580 @default.
• W2034162787 cites W2156751159 @default.
• W2034162787 cites W2329505675 @default.
• W2034162787 cites W2409022042 @default.
• W2034162787 cites W4245008793 @default.
• W2034162787 doi "https://doi.org/10.1021/pr700793k" @default.
• W2034162787 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18624397" @default.
• W2034162787 hasPublicationYear "2008" @default.
• W2034162787 type Work @default.
• W2034162787 sameAs 2034162787 @default.
• W2034162787 citedByCount "84" @default.
• W2034162787 countsByYear W20341627872012 @default.
• W2034162787 countsByYear W20341627872013 @default.
• W2034162787 countsByYear W20341627872014 @default.
• W2034162787 countsByYear W20341627872015 @default.
• W2034162787 countsByYear W20341627872016 @default.
• W2034162787 countsByYear W20341627872017 @default.
• W2034162787 countsByYear W20341627872018 @default.
• W2034162787 countsByYear W20341627872019 @default.
• W2034162787 countsByYear W20341627872020 @default.
• W2034162787 countsByYear W20341627872021 @default.
• W2034162787 countsByYear W20341627872022 @default.
• W2034162787 countsByYear W20341627872023 @default.
• W2034162787 crossrefType "journal-article" @default.
• W2034162787 hasAuthorship W2034162787A5020306466 @default.
• W2034162787 hasAuthorship W2034162787A5023684865 @default.
• W2034162787 hasAuthorship W2034162787A5029523842 @default.
• W2034162787 hasAuthorship W2034162787A5036445169 @default.
• W2034162787 hasAuthorship W2034162787A5043680660 @default.
• W2034162787 hasAuthorship W2034162787A5067372054 @default.
• W2034162787 hasConcept C108625454 @default.
• W2034162787 hasConcept C147483822 @default.
• W2034162787 hasConcept C159654299 @default.
• W2034162787 hasConcept C179264091 @default.
• W2034162787 hasConcept C185592680 @default.
• W2034162787 hasConcept C195616568 @default.
• W2034162787 hasConcept C203014093 @default.
• W2034162787 hasConcept C2776841590 @default.
• W2034162787 hasConcept C2777726330 @default.
• W2034162787 hasConcept C2778717857 @default.
• W2034162787 hasConcept C2779073587 @default.
• W2034162787 hasConcept C2992940123 @default.
• W2034162787 hasConcept C3020171069 @default.
• W2034162787 hasConcept C31903555 @default.
• W2034162787 hasConcept C55493867 @default.
• W2034162787 hasConcept C61507768 @default.
• W2034162787 hasConcept C86803240 @default.
• W2034162787 hasConceptScore W2034162787C108625454 @default.
• W2034162787 hasConceptScore W2034162787C147483822 @default.
• W2034162787 hasConceptScore W2034162787C159654299 @default.
• W2034162787 hasConceptScore W2034162787C179264091 @default.
• W2034162787 hasConceptScore W2034162787C185592680 @default.
• W2034162787 hasConceptScore W2034162787C195616568 @default.
• W2034162787 hasConceptScore W2034162787C203014093 @default.
• W2034162787 hasConceptScore W2034162787C2776841590 @default.
• W2034162787 hasConceptScore W2034162787C2777726330 @default.
• W2034162787 hasConceptScore W2034162787C2778717857 @default.
• W2034162787 hasConceptScore W2034162787C2779073587 @default.
• W2034162787 hasConceptScore W2034162787C2992940123 @default.
• W2034162787 hasConceptScore W2034162787C3020171069 @default.
• W2034162787 hasConceptScore W2034162787C31903555 @default.
• W2034162787 hasConceptScore W2034162787C55493867 @default.
• W2034162787 hasConceptScore W2034162787C61507768 @default.

• next