Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034163025> ?p ?o ?g. }
- W2034163025 endingPage "1304" @default.
- W2034163025 startingPage "1289" @default.
- W2034163025 abstract "Aims: High salinity stress impairs plant growth and development. Trehalose metabolism has been implicated in sugar signaling, and enhanced trehalose metabolism can positively regulate abiotic stress tolerance. However, the molecular mechanism(s) of the stress-related trehalose pathway and the role of individual trehalose biosynthetic enzymes for stress tolerance remain unclear. Results: Trehalose-6-phosphate phosphatase (TPP) catalyzes the final step of trehalose metabolism. Investigating the subcellular localization of the Arabidopsis thaliana TPP family members, we identified AtTPPD as a chloroplast-localized enzyme. Plants deficient in AtTPPD were hypersensitive, whereas plants overexpressing AtTPPD were more tolerant to high salinity stress. Elevated stress tolerance of AtTPPD overexpressors correlated with high starch levels and increased accumulation of soluble sugars, suggesting a role for AtTPPD in regulating sugar metabolism under salinity conditions. Biochemical analyses indicate that AtTPPD is a target of post-translational redox regulation and can be reversibly inactivated by oxidizing conditions. Two cysteine residues were identified as the redox-sensitive sites. Structural and mutation analyses suggest that the formation of an intramolecular disulfide bridge regulates AtTPPD activity. Innovation: The activity of different AtTPP isoforms, located in the cytosol, nucleus, and chloroplasts, can be redox regulated, suggesting that the trehalose metabolism might relay the redox status of different cellular compartments to regulate diverse biological processes such as stress responses. Conclusion: The evolutionary conservation of the two redox regulatory cysteine residues of TPPs in spermatophytes indicates that redox regulation of TPPs might be a common mechanism enabling plants to rapidly adjust trehalose metabolism to the prevailing environmental and developmental conditions. Antioxid. Redox Signal. 21, 1289–1304." @default.
- W2034163025 created "2016-06-24" @default.
- W2034163025 creator A5022281259 @default.
- W2034163025 creator A5045714607 @default.
- W2034163025 creator A5052114531 @default.
- W2034163025 creator A5054797114 @default.
- W2034163025 date "2014-09-20" @default.
- W2034163025 modified "2023-10-17" @default.
- W2034163025 title "The Redox-Sensitive Chloroplast Trehalose-6-Phosphate Phosphatase AtTPPD Regulates Salt Stress Tolerance" @default.
- W2034163025 cites W1496601602 @default.
- W2034163025 cites W1543761571 @default.
- W2034163025 cites W1800605248 @default.
- W2034163025 cites W1890612557 @default.
- W2034163025 cites W1918260619 @default.
- W2034163025 cites W1965645988 @default.
- W2034163025 cites W1970741481 @default.
- W2034163025 cites W1971335173 @default.
- W2034163025 cites W1979685879 @default.
- W2034163025 cites W1980267514 @default.
- W2034163025 cites W1982183910 @default.
- W2034163025 cites W1982724915 @default.
- W2034163025 cites W1984425875 @default.
- W2034163025 cites W1984843095 @default.
- W2034163025 cites W1987884021 @default.
- W2034163025 cites W1988314246 @default.
- W2034163025 cites W1990145144 @default.
- W2034163025 cites W1990795092 @default.
- W2034163025 cites W1992104581 @default.
- W2034163025 cites W1993669834 @default.
- W2034163025 cites W1999936984 @default.
- W2034163025 cites W2000633331 @default.
- W2034163025 cites W2000802164 @default.
- W2034163025 cites W2009899621 @default.
- W2034163025 cites W2011067611 @default.
- W2034163025 cites W2014863339 @default.
- W2034163025 cites W2016370480 @default.
- W2034163025 cites W2018003660 @default.
- W2034163025 cites W2019560867 @default.
- W2034163025 cites W2020196381 @default.
- W2034163025 cites W2021289354 @default.
- W2034163025 cites W2022351903 @default.
- W2034163025 cites W2023092914 @default.
- W2034163025 cites W2026361650 @default.
- W2034163025 cites W2027440363 @default.
- W2034163025 cites W2028138051 @default.
- W2034163025 cites W2036875515 @default.
- W2034163025 cites W2041020934 @default.
- W2034163025 cites W2044159567 @default.
- W2034163025 cites W2045291855 @default.
- W2034163025 cites W2056206008 @default.
- W2034163025 cites W2059172925 @default.
- W2034163025 cites W2059724382 @default.
- W2034163025 cites W2063879178 @default.
- W2034163025 cites W2064441370 @default.
- W2034163025 cites W2065744015 @default.
- W2034163025 cites W2066224879 @default.
- W2034163025 cites W2067424303 @default.
- W2034163025 cites W2068756350 @default.
- W2034163025 cites W2069083282 @default.
- W2034163025 cites W207050664 @default.
- W2034163025 cites W2073317899 @default.
- W2034163025 cites W2074690290 @default.
- W2034163025 cites W2075466234 @default.
- W2034163025 cites W2076685684 @default.
- W2034163025 cites W2077081557 @default.
- W2034163025 cites W2078168232 @default.
- W2034163025 cites W2086491289 @default.
- W2034163025 cites W2089367940 @default.
- W2034163025 cites W2090189626 @default.
- W2034163025 cites W2093187049 @default.
- W2034163025 cites W2097118576 @default.
- W2034163025 cites W2099825899 @default.
- W2034163025 cites W2102167165 @default.
- W2034163025 cites W2104844840 @default.
- W2034163025 cites W2107277218 @default.
- W2034163025 cites W2112594199 @default.
- W2034163025 cites W2116304145 @default.
- W2034163025 cites W2117759423 @default.
- W2034163025 cites W2118688605 @default.
- W2034163025 cites W2119404103 @default.
- W2034163025 cites W2134170219 @default.
- W2034163025 cites W2137381764 @default.
- W2034163025 cites W2138505669 @default.
- W2034163025 cites W2140791476 @default.
- W2034163025 cites W2145419814 @default.
- W2034163025 cites W2146230521 @default.
- W2034163025 cites W2148717014 @default.
- W2034163025 cites W2150434569 @default.
- W2034163025 cites W2152301430 @default.
- W2034163025 cites W2154140763 @default.
- W2034163025 cites W2154173720 @default.
- W2034163025 cites W2155758352 @default.
- W2034163025 cites W2156350829 @default.
- W2034163025 cites W2157460239 @default.
- W2034163025 cites W2158714788 @default.
- W2034163025 cites W2160943048 @default.
- W2034163025 cites W2164944073 @default.
- W2034163025 cites W2258647781 @default.