Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034164043> ?p ?o ?g. }
- W2034164043 endingPage "4029" @default.
- W2034164043 startingPage "4021" @default.
- W2034164043 abstract "Platelets can bind and phagocytose infectious microorganisms and so enable their transport for a prolonged time. To investigate the subcellular events of these interactions, platelets were incubated either with Staphylococcus aureus or with HIV and analyzed by electron microscopy (EM) and immuno-EM. HIV and bacteria internalization occurred exclusively within platelets showing morphological evidence of activation. Platelet activation enhanced the degree of bacterial internalization. Immunolabeling revealed that the engulfing vacuoles and the open canalicular system (OCS) were composed of distinct antigens. The engulfing vacuoles eventually became the site of prominent α-granule release. In platelets incubated with HIV, characteristic endocytic vacuoles were identified close to the plasma membrane, tightly surrounding 1 or 2 HIV particles. Virus particles were also located within the OCS. Immunogold labeling for the viral core protein p24 confirmed the presence of HIV within platelets. Finally, examination of platelets from a patient with acquired immunodeficiency syndrome and high viremia suggested that HIV endocytosis may also occur in vivo." @default.
- W2034164043 created "2016-06-24" @default.
- W2034164043 creator A5008680725 @default.
- W2034164043 creator A5059277083 @default.
- W2034164043 creator A5068100566 @default.
- W2034164043 creator A5080326131 @default.
- W2034164043 creator A5088801559 @default.
- W2034164043 date "2002-06-01" @default.
- W2034164043 modified "2023-10-14" @default.
- W2034164043 title "Host defense role of platelets: engulfment of HIV andStaphylococcus aureus occurs in a specific subcellular compartment and is enhanced by platelet activation" @default.
- W2034164043 cites W113835883 @default.
- W2034164043 cites W158506035 @default.
- W2034164043 cites W1596926175 @default.
- W2034164043 cites W1629000899 @default.
- W2034164043 cites W1757310287 @default.
- W2034164043 cites W1886185926 @default.
- W2034164043 cites W1935159686 @default.
- W2034164043 cites W1966285451 @default.
- W2034164043 cites W1973590064 @default.
- W2034164043 cites W1984811742 @default.
- W2034164043 cites W1989025673 @default.
- W2034164043 cites W1996038916 @default.
- W2034164043 cites W2005972873 @default.
- W2034164043 cites W2017870785 @default.
- W2034164043 cites W2026240949 @default.
- W2034164043 cites W2029218146 @default.
- W2034164043 cites W2045403351 @default.
- W2034164043 cites W2074175352 @default.
- W2034164043 cites W2088747167 @default.
- W2034164043 cites W2097480719 @default.
- W2034164043 cites W2126844603 @default.
- W2034164043 cites W2140452348 @default.
- W2034164043 cites W2152379670 @default.
- W2034164043 cites W2164436324 @default.
- W2034164043 cites W2248336029 @default.
- W2034164043 cites W226237940 @default.
- W2034164043 cites W2403058886 @default.
- W2034164043 cites W2409811498 @default.
- W2034164043 cites W2412745323 @default.
- W2034164043 cites W293390614 @default.
- W2034164043 cites W298920371 @default.
- W2034164043 cites W40825427 @default.
- W2034164043 cites W4239414389 @default.
- W2034164043 cites W4243233723 @default.
- W2034164043 cites W4254175543 @default.
- W2034164043 cites W94129673 @default.
- W2034164043 doi "https://doi.org/10.1182/blood-2001-12-0191" @default.
- W2034164043 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12010803" @default.
- W2034164043 hasPublicationYear "2002" @default.
- W2034164043 type Work @default.
- W2034164043 sameAs 2034164043 @default.
- W2034164043 citedByCount "267" @default.
- W2034164043 countsByYear W20341640432012 @default.
- W2034164043 countsByYear W20341640432013 @default.
- W2034164043 countsByYear W20341640432014 @default.
- W2034164043 countsByYear W20341640432015 @default.
- W2034164043 countsByYear W20341640432016 @default.
- W2034164043 countsByYear W20341640432017 @default.
- W2034164043 countsByYear W20341640432018 @default.
- W2034164043 countsByYear W20341640432019 @default.
- W2034164043 countsByYear W20341640432020 @default.
- W2034164043 countsByYear W20341640432021 @default.
- W2034164043 countsByYear W20341640432022 @default.
- W2034164043 countsByYear W20341640432023 @default.
- W2034164043 crossrefType "journal-article" @default.
- W2034164043 hasAuthorship W2034164043A5008680725 @default.
- W2034164043 hasAuthorship W2034164043A5059277083 @default.
- W2034164043 hasAuthorship W2034164043A5068100566 @default.
- W2034164043 hasAuthorship W2034164043A5080326131 @default.
- W2034164043 hasAuthorship W2034164043A5088801559 @default.
- W2034164043 hasBestOaLocation W20341640431 @default.
- W2034164043 hasConcept C102568950 @default.
- W2034164043 hasConcept C102747710 @default.
- W2034164043 hasConcept C139770010 @default.
- W2034164043 hasConcept C1491633281 @default.
- W2034164043 hasConcept C159654299 @default.
- W2034164043 hasConcept C160448771 @default.
- W2034164043 hasConcept C168507396 @default.
- W2034164043 hasConcept C190062978 @default.
- W2034164043 hasConcept C203014093 @default.
- W2034164043 hasConcept C204232928 @default.
- W2034164043 hasConcept C2777877921 @default.
- W2034164043 hasConcept C28005876 @default.
- W2034164043 hasConcept C30030713 @default.
- W2034164043 hasConcept C3018697912 @default.
- W2034164043 hasConcept C55493867 @default.
- W2034164043 hasConcept C79747257 @default.
- W2034164043 hasConcept C79879829 @default.
- W2034164043 hasConcept C86803240 @default.
- W2034164043 hasConcept C89372155 @default.
- W2034164043 hasConcept C89560881 @default.
- W2034164043 hasConcept C95444343 @default.
- W2034164043 hasConceptScore W2034164043C102568950 @default.
- W2034164043 hasConceptScore W2034164043C102747710 @default.
- W2034164043 hasConceptScore W2034164043C139770010 @default.
- W2034164043 hasConceptScore W2034164043C1491633281 @default.
- W2034164043 hasConceptScore W2034164043C159654299 @default.
- W2034164043 hasConceptScore W2034164043C160448771 @default.