Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034167987> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2034167987 endingPage "3" @default.
- W2034167987 startingPage "1" @default.
- W2034167987 abstract "In order to clarify whether a dietary fiber has any effect upon the intestinal absorption of sulfonylurea, changes in plasma concentration of glibenclamide were determined during a six-hour period in nine healthy volunteers who took 2.5 mg of glibenclamide together with a breakfast and 3.9 g of glucomannan in a form of konjac powder and were compared with those of the control experiment in which the same amount of the hypoglycemic agent was given without the dietary fiber. In the control, mean plasma glibenclamide level increased rapidly, reaching a peak at 60 min and decreased gradually thereafter, whereas an increase in plasma glibenclamide level was blunted in the test experiment, thus plasma concentration of glibenclamide being lower at 30, 60, 90 and 150 min compared with the corresponding value of the control (31.7 +/- 24.5 ng/ml vs 76.4 +/- 25.0 ng/ml at 30 min; 51.3 +/- 35.5 ng/ml vs 120.9 +/- 56.0 ng/ml at 60 min; 60.0 +/- 38.8 ng/ml vs 117.4 +/- 53.1 ng/ml at 90 min; 54.0 +/- 31.5 ng/ml vs 100.7 +/- 46.5 ng/ml at 150 min). Mean plasma glucose concentration was significantly lower at 30 min in the test experiment than in the control despite the lower level of plasma glibenclamide in the former. The results suggest that glucomannan may influence the intestinal absorption of glibenclamide. A dietary fiber must be prescribed in due consideration of these facts." @default.
- W2034167987 created "2016-06-24" @default.
- W2034167987 creator A5030012941 @default.
- W2034167987 creator A5041031018 @default.
- W2034167987 creator A5046392787 @default.
- W2034167987 creator A5068880382 @default.
- W2034167987 creator A5082363422 @default.
- W2034167987 creator A5083862404 @default.
- W2034167987 date "1983-01-01" @default.
- W2034167987 modified "2023-09-27" @default.
- W2034167987 title "Effect of Dietary Fiber, Glucomannan, on Absorption of Sulfonylurea in Man" @default.
- W2034167987 doi "https://doi.org/10.1055/s-2007-1018613" @default.
- W2034167987 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6299917" @default.
- W2034167987 hasPublicationYear "1983" @default.
- W2034167987 type Work @default.
- W2034167987 sameAs 2034167987 @default.
- W2034167987 citedByCount "37" @default.
- W2034167987 countsByYear W20341679872013 @default.
- W2034167987 countsByYear W20341679872014 @default.
- W2034167987 countsByYear W20341679872015 @default.
- W2034167987 countsByYear W20341679872017 @default.
- W2034167987 countsByYear W20341679872018 @default.
- W2034167987 countsByYear W20341679872019 @default.
- W2034167987 countsByYear W20341679872021 @default.
- W2034167987 countsByYear W20341679872022 @default.
- W2034167987 countsByYear W20341679872023 @default.
- W2034167987 crossrefType "journal-article" @default.
- W2034167987 hasAuthorship W2034167987A5030012941 @default.
- W2034167987 hasAuthorship W2034167987A5041031018 @default.
- W2034167987 hasAuthorship W2034167987A5046392787 @default.
- W2034167987 hasAuthorship W2034167987A5068880382 @default.
- W2034167987 hasAuthorship W2034167987A5082363422 @default.
- W2034167987 hasAuthorship W2034167987A5083862404 @default.
- W2034167987 hasConcept C125287762 @default.
- W2034167987 hasConcept C126322002 @default.
- W2034167987 hasConcept C134018914 @default.
- W2034167987 hasConcept C140793950 @default.
- W2034167987 hasConcept C159985019 @default.
- W2034167987 hasConcept C185592680 @default.
- W2034167987 hasConcept C192562407 @default.
- W2034167987 hasConcept C2778854520 @default.
- W2034167987 hasConcept C2779768347 @default.
- W2034167987 hasConcept C2780179618 @default.
- W2034167987 hasConcept C2992741425 @default.
- W2034167987 hasConcept C3020079912 @default.
- W2034167987 hasConcept C31903555 @default.
- W2034167987 hasConcept C555293320 @default.
- W2034167987 hasConcept C71924100 @default.
- W2034167987 hasConcept C86803240 @default.
- W2034167987 hasConceptScore W2034167987C125287762 @default.
- W2034167987 hasConceptScore W2034167987C126322002 @default.
- W2034167987 hasConceptScore W2034167987C134018914 @default.
- W2034167987 hasConceptScore W2034167987C140793950 @default.
- W2034167987 hasConceptScore W2034167987C159985019 @default.
- W2034167987 hasConceptScore W2034167987C185592680 @default.
- W2034167987 hasConceptScore W2034167987C192562407 @default.
- W2034167987 hasConceptScore W2034167987C2778854520 @default.
- W2034167987 hasConceptScore W2034167987C2779768347 @default.
- W2034167987 hasConceptScore W2034167987C2780179618 @default.
- W2034167987 hasConceptScore W2034167987C2992741425 @default.
- W2034167987 hasConceptScore W2034167987C3020079912 @default.
- W2034167987 hasConceptScore W2034167987C31903555 @default.
- W2034167987 hasConceptScore W2034167987C555293320 @default.
- W2034167987 hasConceptScore W2034167987C71924100 @default.
- W2034167987 hasConceptScore W2034167987C86803240 @default.
- W2034167987 hasIssue "01" @default.
- W2034167987 hasLocation W20341679871 @default.
- W2034167987 hasLocation W20341679872 @default.
- W2034167987 hasOpenAccess W2034167987 @default.
- W2034167987 hasPrimaryLocation W20341679871 @default.
- W2034167987 hasRelatedWork W1968813451 @default.
- W2034167987 hasRelatedWork W1973174554 @default.
- W2034167987 hasRelatedWork W2019604928 @default.
- W2034167987 hasRelatedWork W2029170600 @default.
- W2034167987 hasRelatedWork W2034167987 @default.
- W2034167987 hasRelatedWork W2067441476 @default.
- W2034167987 hasRelatedWork W2071138625 @default.
- W2034167987 hasRelatedWork W2137971781 @default.
- W2034167987 hasRelatedWork W2917502842 @default.
- W2034167987 hasRelatedWork W4254115420 @default.
- W2034167987 hasVolume "15" @default.
- W2034167987 isParatext "false" @default.
- W2034167987 isRetracted "false" @default.
- W2034167987 magId "2034167987" @default.
- W2034167987 workType "article" @default.