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- W2034169605 abstract "Recent accumulating evidence revealed that planarian central nervous system (CNS) has numerous functional domains distinguished by a large number of neural markers, suggesting that primitive animals which developed CNS already had the framework of the brain development. It is of interest to investigate genes which have been acquired at an early stage of evolution for brain pattern formation. One such candidate is FoxG1 (BF-1), specifically expressed in the telencephalon and implicated in brain development. We identified a FoxG1 (BF-1) homolog gene in planarians (DjFoxG). We also identified a FoxD class gene, DjFoxD. DjFoxG is expressed in the body and brain, with strong expression in the mesenchyme surrounding the gut. During regeneration, an intense anterior signal is detected, but this is not restricted to the head. DjFoxD is expressed in the mid-apex of the head, between the two lobes of the brain. Strong expression was detected in the mid-anterior blastema. Thus, FoxG and FoxD homologs do exist in planarians, but are regulated differently than those in vertebrates." @default.
- W2034169605 created "2016-06-24" @default.
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- W2034169605 date "2003-03-01" @default.
- W2034169605 modified "2023-10-17" @default.
- W2034169605 title "The expression of planarian brain factor homologs, DjFoxG and DjFoxD" @default.
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- W2034169605 doi "https://doi.org/10.1016/s1567-133x(02)00097-2" @default.
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