FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034171026> ?p ?o ?g. }

• W2034171026 endingPage "1860" @default.
• W2034171026 startingPage "1853" @default.
• W2034171026 abstract "Electrochemical detection has been developed and assay performances studied for the CombiMatrix oligonucleotide microarray platform that contains 12,544 individually addressable microelectrodes (features) in a semiconductor matrix. The approach is based on the detection of redox active chemistries (such as horseradish peroxidase (HRP) and the associated substrate TMB) proximal to specific microarray electrodes. First, microarray probes are hybridized to biotin-labeled targets, second, the HRP-streptavidin conjugate binds to biotin, and enzymatic oxidation of the electron donor substrate then occurs. The detection current is generated due to electro-reduction of the HRP reaction product, and it is measured with the CombiMatrix ElectraSense™ Reader. Performance of the ElectraSense™ platform has been characterized using gene expression and genotyping assays to analyze: (i) signal to concentration dependence, (ii) assay resolution, (iii) coefficients of variation, (CV) and (iv) array-to-array reproducibility and data correlation. The ElectraSense™ platform was also compared to the standard fluorescent detection, and good consistency was observed between these two different detection techniques. A lower detection limit of 0.75 pM was obtained for ElectraSense™ as compared to the detection limit of 1.5 pM obtained for fluorescent detection. Thus, the ElectraSense™ platform has been used to develop nucleic acid assays for highly accurate genotyping of a variety of pathogens including bio-threat agents (such as Bacillus anthracis, Yersinia pestis, and other microorganisms including Escherichia coli, Bacillus subtilis, etc.) and common pathogens of the respiratory tract (e.g. influenza A virus)." @default.
• W2034171026 created "2016-06-24" @default.
• W2034171026 creator A5013732063 @default.
• W2034171026 creator A5024549083 @default.
• W2034171026 creator A5025399569 @default.
• W2034171026 creator A5040722582 @default.
• W2034171026 creator A5046994497 @default.
• W2034171026 creator A5053652380 @default.
• W2034171026 creator A5063000689 @default.
• W2034171026 creator A5065586830 @default.
• W2034171026 creator A5066627209 @default.
• W2034171026 creator A5084036815 @default.
• W2034171026 creator A5085305122 @default.
• W2034171026 date "2007-04-01" @default.
• W2034171026 modified "2023-09-27" @default.
• W2034171026 title "CombiMatrix oligonucleotide arrays: Genotyping and gene expression assays employing electrochemical detection" @default.
• W2034171026 cites W1502936039 @default.
• W2034171026 cites W1576737979 @default.
• W2034171026 cites W2000312272 @default.
• W2034171026 cites W2032529289 @default.
• W2034171026 cites W2041033156 @default.
• W2034171026 cites W2059288813 @default.
• W2034171026 cites W2072022112 @default.
• W2034171026 cites W2103414463 @default.
• W2034171026 cites W2108694342 @default.
• W2034171026 cites W2116146003 @default.
• W2034171026 cites W2125996679 @default.
• W2034171026 cites W2132561013 @default.
• W2034171026 cites W2141009231 @default.
• W2034171026 cites W2144120272 @default.
• W2034171026 cites W2150213253 @default.
• W2034171026 cites W2161447932 @default.
• W2034171026 doi "https://doi.org/10.1016/j.bios.2006.06.024" @default.
• W2034171026 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16891109" @default.
• W2034171026 hasPublicationYear "2007" @default.
• W2034171026 type Work @default.
• W2034171026 sameAs 2034171026 @default.
• W2034171026 citedByCount "145" @default.
• W2034171026 countsByYear W20341710262012 @default.
• W2034171026 countsByYear W20341710262013 @default.
• W2034171026 countsByYear W20341710262014 @default.
• W2034171026 countsByYear W20341710262015 @default.
• W2034171026 countsByYear W20341710262016 @default.
• W2034171026 countsByYear W20341710262017 @default.
• W2034171026 countsByYear W20341710262018 @default.
• W2034171026 countsByYear W20341710262019 @default.
• W2034171026 countsByYear W20341710262020 @default.
• W2034171026 countsByYear W20341710262021 @default.
• W2034171026 countsByYear W20341710262022 @default.
• W2034171026 countsByYear W20341710262023 @default.
• W2034171026 crossrefType "journal-article" @default.
• W2034171026 hasAuthorship W2034171026A5013732063 @default.
• W2034171026 hasAuthorship W2034171026A5024549083 @default.
• W2034171026 hasAuthorship W2034171026A5025399569 @default.
• W2034171026 hasAuthorship W2034171026A5040722582 @default.
• W2034171026 hasAuthorship W2034171026A5046994497 @default.
• W2034171026 hasAuthorship W2034171026A5053652380 @default.
• W2034171026 hasAuthorship W2034171026A5063000689 @default.
• W2034171026 hasAuthorship W2034171026A5065586830 @default.
• W2034171026 hasAuthorship W2034171026A5066627209 @default.
• W2034171026 hasAuthorship W2034171026A5084036815 @default.
• W2034171026 hasAuthorship W2034171026A5085305122 @default.
• W2034171026 hasConcept C104317684 @default.
• W2034171026 hasConcept C119128265 @default.
• W2034171026 hasConcept C129312508 @default.
• W2034171026 hasConcept C135763542 @default.
• W2034171026 hasConcept C150194340 @default.
• W2034171026 hasConcept C153911025 @default.
• W2034171026 hasConcept C160756335 @default.
• W2034171026 hasConcept C181199279 @default.
• W2034171026 hasConcept C185592680 @default.
• W2034171026 hasConcept C24107716 @default.
• W2034171026 hasConcept C2776190903 @default.
• W2034171026 hasConcept C2777676563 @default.
• W2034171026 hasConcept C2778204606 @default.
• W2034171026 hasConcept C31467283 @default.
• W2034171026 hasConcept C43617362 @default.
• W2034171026 hasConcept C552990157 @default.
• W2034171026 hasConcept C55493867 @default.
• W2034171026 hasConcept C86803240 @default.
• W2034171026 hasConcept C95371953 @default.
• W2034171026 hasConceptScore W2034171026C104317684 @default.
• W2034171026 hasConceptScore W2034171026C119128265 @default.
• W2034171026 hasConceptScore W2034171026C129312508 @default.
• W2034171026 hasConceptScore W2034171026C135763542 @default.
• W2034171026 hasConceptScore W2034171026C150194340 @default.
• W2034171026 hasConceptScore W2034171026C153911025 @default.
• W2034171026 hasConceptScore W2034171026C160756335 @default.
• W2034171026 hasConceptScore W2034171026C181199279 @default.
• W2034171026 hasConceptScore W2034171026C185592680 @default.
• W2034171026 hasConceptScore W2034171026C24107716 @default.
• W2034171026 hasConceptScore W2034171026C2776190903 @default.
• W2034171026 hasConceptScore W2034171026C2777676563 @default.
• W2034171026 hasConceptScore W2034171026C2778204606 @default.
• W2034171026 hasConceptScore W2034171026C31467283 @default.
• W2034171026 hasConceptScore W2034171026C43617362 @default.
• W2034171026 hasConceptScore W2034171026C552990157 @default.
• W2034171026 hasConceptScore W2034171026C55493867 @default.

• next