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• W2034175214 abstract "Accumulating evidence suggests that testosterone has neurotrophic and perhaps neuroprotective actions. Thus, age-related depletion of testosterone may increase the brain's vulnerability to Alzheimer's disease and related disorders. To begin investigating this issue, cultured neurons were exposed to the Alzheimer-related insult beta-amyloid in the presence of testosterone. beta-Amyloid neurotoxicity was significantly reduced by testosterone via a rapid, estrogen-independent mechanism. These data may provide additional insight into the treatment of age-related neurodegenerative disorders." @default.
• W2034175214 created "2016-06-24" @default.
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• W2034175214 date "2001-11-01" @default.
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• W2034175214 title "Testosterone attenuates β-amyloid toxicity in cultured hippocampal neurons" @default.
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• W2034175214 doi "https://doi.org/10.1016/s0006-8993(01)03024-4" @default.
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