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- W2034182647 abstract "The gastrointestinal immune system consists of immune cells in organized gut-associated lymphoreticular tissues (GALT) and diffuse lamina propria, which give rise to mucosal secretory IgA antibody responses. A recent study showed that the retinoic acid produced by GALT dendritic cells (DCs) imprints B cells for gut homing. Surprisingly, GALT DCs, together with interleukin-5 (IL-5) and IL-6, also provided a milieu for both B cell switching to IgA and IgA synthesis. The gastrointestinal immune system consists of immune cells in organized gut-associated lymphoreticular tissues (GALT) and diffuse lamina propria, which give rise to mucosal secretory IgA antibody responses. A recent study showed that the retinoic acid produced by GALT dendritic cells (DCs) imprints B cells for gut homing. Surprisingly, GALT DCs, together with interleukin-5 (IL-5) and IL-6, also provided a milieu for both B cell switching to IgA and IgA synthesis." @default.
- W2034182647 created "2016-06-24" @default.
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- W2034182647 date "2007-04-01" @default.
- W2034182647 modified "2023-10-17" @default.
- W2034182647 title "Gut lymphocyte migration: we are halfway ‘home’" @default.
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- W2034182647 doi "https://doi.org/10.1016/j.it.2007.02.001" @default.
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