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- W2034196066 abstract "The effects of Bay K 8644 [methyl-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)-pyridine-5-carboxylate], a calcium channel agonist, on renin release in rat kidney cortical slices were examined. Bay K 8644 produced a dose-related inhibition of renin release in the presence of 15 mM potassium. The inhibitory effect of Bay K 8644 on this release was abolished when calcium was excluded from the incubation medium. Nifedipine exerted a concentration-dependent blocking action on the inhibition of renin release by Bay K 8644. These findings support the proposal that calcium influx into the renin secretory cells is an inhibitory signal for renin release." @default.
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- W2034196066 title "The calcium channel agonist, Bay K 8644, inhibits renin release from rat kidney cortical slices" @default.
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- W2034196066 doi "https://doi.org/10.1016/0014-2999(85)90011-1" @default.
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