Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034199666> ?p ?o ?g. }
- W2034199666 endingPage "151" @default.
- W2034199666 startingPage "151" @default.
- W2034199666 abstract "This paper briefly reviews the literature on testicular descent and presents new observations from the authors' laboratory which suggest new ways of looking at old problems. There is now good evidence that testicular descent occurs in two morphologically and hormonally distinct phases. Relative 'transabdominal migration' of the testis compared with the ovary occurs at 10-15 weeks of gestation in the human and 'inguinoscrotal' migration occurs at 26-35 weeks of gestation. We have proposed previously that the first phase is controlled by Müllerian inhibiting substance although this remains controversial. The second phase is androgen dependent and is possibly mediated indirectly through the release from the genitofemoral nerve (GFN) of the neuropeptide calcitonin gene-related peptide (CGRP). Recently we have used three different rodent models of undescended testis to determine the involvement of the GNF and/or CGRP. The testicular feminization mouse with complete androgen resistance and the rat exposed prenatally to the antiandrogen flutamide have a deficiency of CGRP in the GFN. In contrast, the mutant trans-scrotal rat which has normal androgen levels has an excess of CGRP in the GFN. All cryptorchidism models, despite their different primary cause, have in common an abnormality of the GNF and/or CGRP which is consistent with the hypothesis that normal testicular descent in the rodent may be mediated by the GFN." @default.
- W2034199666 created "2016-06-24" @default.
- W2034199666 creator A5028995581 @default.
- W2034199666 creator A5042289644 @default.
- W2034199666 creator A5051928369 @default.
- W2034199666 creator A5071307888 @default.
- W2034199666 creator A5069803743 @default.
- W2034199666 date "1994-01-01" @default.
- W2034199666 modified "2023-09-27" @default.
- W2034199666 title "Hormonal control of testicular descent and the cause of cryptorchidism" @default.
- W2034199666 cites W161883716 @default.
- W2034199666 cites W1965423636 @default.
- W2034199666 cites W1966205013 @default.
- W2034199666 cites W1966492896 @default.
- W2034199666 cites W1967004073 @default.
- W2034199666 cites W1972927310 @default.
- W2034199666 cites W1974125792 @default.
- W2034199666 cites W1974844037 @default.
- W2034199666 cites W1983525180 @default.
- W2034199666 cites W1985624113 @default.
- W2034199666 cites W1991835307 @default.
- W2034199666 cites W1995601298 @default.
- W2034199666 cites W1997378719 @default.
- W2034199666 cites W2025993371 @default.
- W2034199666 cites W2027900040 @default.
- W2034199666 cites W2030839274 @default.
- W2034199666 cites W2033576794 @default.
- W2034199666 cites W2033620239 @default.
- W2034199666 cites W2037116229 @default.
- W2034199666 cites W2039242322 @default.
- W2034199666 cites W2043844290 @default.
- W2034199666 cites W2047654499 @default.
- W2034199666 cites W2049483982 @default.
- W2034199666 cites W2060904319 @default.
- W2034199666 cites W2061568116 @default.
- W2034199666 cites W2063334947 @default.
- W2034199666 cites W2077279494 @default.
- W2034199666 cites W2079806414 @default.
- W2034199666 cites W2081484147 @default.
- W2034199666 cites W2084263177 @default.
- W2034199666 cites W2085754991 @default.
- W2034199666 cites W2117715291 @default.
- W2034199666 cites W2135877655 @default.
- W2034199666 cites W2152848856 @default.
- W2034199666 cites W2156273323 @default.
- W2034199666 cites W2161383304 @default.
- W2034199666 cites W2162050290 @default.
- W2034199666 cites W2403349481 @default.
- W2034199666 cites W2413311985 @default.
- W2034199666 cites W2417645865 @default.
- W2034199666 cites W2438857919 @default.
- W2034199666 cites W2466749539 @default.
- W2034199666 cites W376004220 @default.
- W2034199666 cites W397972454 @default.
- W2034199666 cites W642402266 @default.
- W2034199666 cites W643664272 @default.
- W2034199666 cites W72388677 @default.
- W2034199666 cites W79636048 @default.
- W2034199666 cites W91260704 @default.
- W2034199666 doi "https://doi.org/10.1071/rd9940151" @default.
- W2034199666 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7991782" @default.
- W2034199666 hasPublicationYear "1994" @default.
- W2034199666 type Work @default.
- W2034199666 sameAs 2034199666 @default.
- W2034199666 citedByCount "89" @default.
- W2034199666 countsByYear W20341996662012 @default.
- W2034199666 countsByYear W20341996662013 @default.
- W2034199666 countsByYear W20341996662015 @default.
- W2034199666 countsByYear W20341996662016 @default.
- W2034199666 countsByYear W20341996662017 @default.
- W2034199666 countsByYear W20341996662018 @default.
- W2034199666 countsByYear W20341996662019 @default.
- W2034199666 countsByYear W20341996662020 @default.
- W2034199666 countsByYear W20341996662021 @default.
- W2034199666 countsByYear W20341996662022 @default.
- W2034199666 crossrefType "journal-article" @default.
- W2034199666 hasAuthorship W2034199666A5028995581 @default.
- W2034199666 hasAuthorship W2034199666A5042289644 @default.
- W2034199666 hasAuthorship W2034199666A5051928369 @default.
- W2034199666 hasAuthorship W2034199666A5069803743 @default.
- W2034199666 hasAuthorship W2034199666A5071307888 @default.
- W2034199666 hasConcept C118303440 @default.
- W2034199666 hasConcept C121608353 @default.
- W2034199666 hasConcept C126322002 @default.
- W2034199666 hasConcept C134018914 @default.
- W2034199666 hasConcept C163170386 @default.
- W2034199666 hasConcept C166516326 @default.
- W2034199666 hasConcept C170493617 @default.
- W2034199666 hasConcept C2777911890 @default.
- W2034199666 hasConcept C2778313021 @default.
- W2034199666 hasConcept C2779627488 @default.
- W2034199666 hasConcept C2780192828 @default.
- W2034199666 hasConcept C3019229404 @default.
- W2034199666 hasConcept C61367390 @default.
- W2034199666 hasConcept C71315377 @default.
- W2034199666 hasConcept C71924100 @default.
- W2034199666 hasConcept C86803240 @default.
- W2034199666 hasConceptScore W2034199666C118303440 @default.