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• W2034201004 abstract "Kcv (K(+) Chlorella virus) is a miniature virus-encoded K(+) channel. Its predicted membrane-pore-membrane structure lacks a cytoplasmic C-terminus and it has a short 12 amino acid (aa) cytoplasmic N-terminus. Kcv forms a functional channel when expressed in human HEK 293 cells. Deletion of the 14 N-terminal aa results in no apparent differences in the subcellular location and expression level of the Kcv protein. However, the truncated protein does not induce a measurable current in transfected HEK 293 cells or Xenopus oocytes. We conclude that the N-terminus controls functional properties of the Kcv channel, but does not influence protein expression." @default.
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• W2034201004 date "2002-09-19" @default.
• W2034201004 modified "2023-10-01" @default.
• W2034201004 title "The short N-terminus is required for functional expression of the virus-encoded miniature K⁺channel Kcv" @default.
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• W2034201004 doi "https://doi.org/10.1016/s0014-5793(02)03397-5" @default.
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