Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034202395> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2034202395 endingPage "53" @default.
- W2034202395 startingPage "48" @default.
- W2034202395 abstract "A simple, rapid and sensitive analytical method for preconcentration and determination of tramadol in different biological samples have been developed using solvent bar microextraction (SBME) combined with gas chromatography–mass spectrometry (GC–MS). The target drugs were extracted from 12 ml of aqueous sample with pH 12.0 (source phase; SP) into an organic extracting solvent (n-nonanol) located inside the pores and lumen of a polypropylene hollow fiber (receiving phase; RP). In order to obtain high extraction efficiency, the effect of different variables on the extraction efficiency was studied using an experimental design. The variables of interest were the type of organic phase, pH of the source phases, ionic strength, volume of the source phase, stirring rate, extraction time and temperature. The experimental parameters of SBME were optimized using a Box–Behnken design (BBD) after a Plackett–Burman screening design. The detection limits were 0.02 μg L−1 with 4.5% RSD (n = 5, c = 10 μg L−1) for tramadol. Finally, the applicability of the proposed method was evaluated by extraction and determination of the drugs in different biological samples. The results indicated that SBME method has excellent clean-up and high-preconcentration factor and can be served as a simple and sensitive method for monitoring of tramadol in the biological samples." @default.
- W2034202395 created "2016-06-24" @default.
- W2034202395 creator A5047460257 @default.
- W2034202395 date "2012-08-01" @default.
- W2034202395 modified "2023-09-23" @default.
- W2034202395 title "Optimization of solvent bar microextraction combined with gas chromatography mass spectrometry for preconcentration and determination of tramadol in biological samples" @default.
- W2034202395 cites W1789513071 @default.
- W2034202395 cites W1970515047 @default.
- W2034202395 cites W1973803878 @default.
- W2034202395 cites W1984262902 @default.
- W2034202395 cites W1990332719 @default.
- W2034202395 cites W1994388891 @default.
- W2034202395 cites W2016806856 @default.
- W2034202395 cites W2025327416 @default.
- W2034202395 cites W2048660409 @default.
- W2034202395 cites W2053330769 @default.
- W2034202395 cites W2056764749 @default.
- W2034202395 cites W2073643789 @default.
- W2034202395 cites W2079486253 @default.
- W2034202395 cites W2080456143 @default.
- W2034202395 cites W2082395255 @default.
- W2034202395 cites W2083283966 @default.
- W2034202395 cites W2094878695 @default.
- W2034202395 cites W2114278959 @default.
- W2034202395 cites W2166455773 @default.
- W2034202395 doi "https://doi.org/10.1016/j.chroma.2012.06.060" @default.
- W2034202395 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22771254" @default.
- W2034202395 hasPublicationYear "2012" @default.
- W2034202395 type Work @default.
- W2034202395 sameAs 2034202395 @default.
- W2034202395 citedByCount "39" @default.
- W2034202395 countsByYear W20342023952013 @default.
- W2034202395 countsByYear W20342023952014 @default.
- W2034202395 countsByYear W20342023952015 @default.
- W2034202395 countsByYear W20342023952016 @default.
- W2034202395 countsByYear W20342023952017 @default.
- W2034202395 countsByYear W20342023952018 @default.
- W2034202395 countsByYear W20342023952019 @default.
- W2034202395 countsByYear W20342023952020 @default.
- W2034202395 countsByYear W20342023952021 @default.
- W2034202395 countsByYear W20342023952022 @default.
- W2034202395 crossrefType "journal-article" @default.
- W2034202395 hasAuthorship W2034202395A5047460257 @default.
- W2034202395 hasConcept C119128265 @default.
- W2034202395 hasConcept C123460561 @default.
- W2034202395 hasConcept C162356407 @default.
- W2034202395 hasConcept C178790620 @default.
- W2034202395 hasConcept C185592680 @default.
- W2034202395 hasConcept C205345274 @default.
- W2034202395 hasConcept C2778533135 @default.
- W2034202395 hasConcept C2778576202 @default.
- W2034202395 hasConcept C2780471494 @default.
- W2034202395 hasConcept C43617362 @default.
- W2034202395 hasConcept C4725764 @default.
- W2034202395 hasConceptScore W2034202395C119128265 @default.
- W2034202395 hasConceptScore W2034202395C123460561 @default.
- W2034202395 hasConceptScore W2034202395C162356407 @default.
- W2034202395 hasConceptScore W2034202395C178790620 @default.
- W2034202395 hasConceptScore W2034202395C185592680 @default.
- W2034202395 hasConceptScore W2034202395C205345274 @default.
- W2034202395 hasConceptScore W2034202395C2778533135 @default.
- W2034202395 hasConceptScore W2034202395C2778576202 @default.
- W2034202395 hasConceptScore W2034202395C2780471494 @default.
- W2034202395 hasConceptScore W2034202395C43617362 @default.
- W2034202395 hasConceptScore W2034202395C4725764 @default.
- W2034202395 hasLocation W20342023951 @default.
- W2034202395 hasLocation W20342023952 @default.
- W2034202395 hasOpenAccess W2034202395 @default.
- W2034202395 hasPrimaryLocation W20342023951 @default.
- W2034202395 hasRelatedWork W2004454890 @default.
- W2034202395 hasRelatedWork W2014079662 @default.
- W2034202395 hasRelatedWork W2037404117 @default.
- W2034202395 hasRelatedWork W2049925796 @default.
- W2034202395 hasRelatedWork W2052310893 @default.
- W2034202395 hasRelatedWork W2080276667 @default.
- W2034202395 hasRelatedWork W2100096104 @default.
- W2034202395 hasRelatedWork W2121137717 @default.
- W2034202395 hasRelatedWork W3161614177 @default.
- W2034202395 hasRelatedWork W65376566 @default.
- W2034202395 hasVolume "1251" @default.
- W2034202395 isParatext "false" @default.
- W2034202395 isRetracted "false" @default.
- W2034202395 magId "2034202395" @default.
- W2034202395 workType "article" @default.