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• W2034206612 abstract "We consider two algorithmic questions related to the evolution of gene families. First, given a gene tree for a gene family, can the evolutionary history of this family be explained with only speciation and duplication events? Such gene trees are called DS-trees. We show that this question can be answered in linear time, and that a DS-tree induces a single species tree. We then study a natural extension of this problem: what is the minimum number of gene losses involved in an evolutionary history leading to an observed gene tree or set of gene trees? Based on our characterization of DS-trees, we propose a heuristic for this problem, and evaluate it on a dataset of plants gene families and on simulated data." @default.
• W2034206612 created "2016-06-24" @default.
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• W2034206612 date "2008-10-01" @default.
• W2034206612 modified "2023-10-03" @default.
• W2034206612 title "Gene Family Evolution by Duplication, Speciation, and Loss" @default.
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• W2034206612 doi "https://doi.org/10.1089/cmb.2008.0054" @default.
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