FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034207391> ?p ?o ?g. }

• W2034207391 endingPage "671" @default.
• W2034207391 startingPage "661" @default.
• W2034207391 abstract "To avoid detection by CTL, HIV encodes mechanisms for removal of class I MHC proteins from the surface of infected cells. However, class I downregulation potentially exposes the virus-infected cell to attack by NK cells. Human lymphoid cells are protected from NK cell cytotoxicity primarily by HLA-C and HLA-E. We present evidence that HIV-1 selectively downregulates HLA-A and HLA-B but does not significantly affect HLA-C or HLA-E. We then identify the residues in HLA-C and HLA-E that protect them from HIV downregulation. This selective downregulation allows HIV-infected cells to avoid NK cell–mediated lysis and may represent for HIV a balance between escape from CTL and maintenance of protection from NK cells. These results suggest that subpopulations of CTL and NK cells may be uniquely suited for combating HIV." @default.
• W2034207391 created "2016-06-24" @default.
• W2034207391 creator A5017875858 @default.
• W2034207391 creator A5026884851 @default.
• W2034207391 creator A5035583924 @default.
• W2034207391 creator A5040129865 @default.
• W2034207391 creator A5042763205 @default.
• W2034207391 creator A5045529124 @default.
• W2034207391 creator A5087187658 @default.
• W2034207391 date "1999-06-01" @default.
• W2034207391 modified "2023-10-14" @default.
• W2034207391 title "The Selective Downregulation of Class I Major Histocompatibility Complex Proteins by HIV-1 Protects HIV-Infected Cells from NK Cells" @default.
• W2034207391 cites W1485698381 @default.
• W2034207391 cites W1629602182 @default.
• W2034207391 cites W1674854702 @default.
• W2034207391 cites W1977786375 @default.
• W2034207391 cites W1982031759 @default.
• W2034207391 cites W1985277896 @default.
• W2034207391 cites W1987275221 @default.
• W2034207391 cites W1994232628 @default.
• W2034207391 cites W2014208459 @default.
• W2034207391 cites W2016296837 @default.
• W2034207391 cites W2029218137 @default.
• W2034207391 cites W2035555649 @default.
• W2034207391 cites W2039266996 @default.
• W2034207391 cites W2051090019 @default.
• W2034207391 cites W2057567758 @default.
• W2034207391 cites W2060621234 @default.
• W2034207391 cites W2063393407 @default.
• W2034207391 cites W2064140853 @default.
• W2034207391 cites W2064558165 @default.
• W2034207391 cites W2077604488 @default.
• W2034207391 cites W2083618683 @default.
• W2034207391 cites W2085279345 @default.
• W2034207391 cites W2094442995 @default.
• W2034207391 cites W2103731776 @default.
• W2034207391 cites W2111235578 @default.
• W2034207391 cites W2116171543 @default.
• W2034207391 cites W2122832461 @default.
• W2034207391 cites W2135733489 @default.
• W2034207391 cites W2144891041 @default.
• W2034207391 cites W2146335364 @default.
• W2034207391 cites W2157588998 @default.
• W2034207391 cites W2160520392 @default.
• W2034207391 cites W2164753292 @default.
• W2034207391 cites W2170830738 @default.
• W2034207391 cites W2173923504 @default.
• W2034207391 cites W2341215846 @default.
• W2034207391 cites W4237567990 @default.
• W2034207391 cites W4240948376 @default.
• W2034207391 cites W6875991 @default.
• W2034207391 doi "https://doi.org/10.1016/s1074-7613(00)80065-5" @default.
• W2034207391 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10403641" @default.
• W2034207391 hasPublicationYear "1999" @default.
• W2034207391 type Work @default.
• W2034207391 sameAs 2034207391 @default.
• W2034207391 citedByCount "821" @default.
• W2034207391 countsByYear W20342073912012 @default.
• W2034207391 countsByYear W20342073912013 @default.
• W2034207391 countsByYear W20342073912014 @default.
• W2034207391 countsByYear W20342073912015 @default.
• W2034207391 countsByYear W20342073912016 @default.
• W2034207391 countsByYear W20342073912017 @default.
• W2034207391 countsByYear W20342073912018 @default.
• W2034207391 countsByYear W20342073912019 @default.
• W2034207391 countsByYear W20342073912020 @default.
• W2034207391 countsByYear W20342073912021 @default.
• W2034207391 countsByYear W20342073912022 @default.
• W2034207391 countsByYear W20342073912023 @default.
• W2034207391 crossrefType "journal-article" @default.
• W2034207391 hasAuthorship W2034207391A5017875858 @default.
• W2034207391 hasAuthorship W2034207391A5026884851 @default.
• W2034207391 hasAuthorship W2034207391A5035583924 @default.
• W2034207391 hasAuthorship W2034207391A5040129865 @default.
• W2034207391 hasAuthorship W2034207391A5042763205 @default.
• W2034207391 hasAuthorship W2034207391A5045529124 @default.
• W2034207391 hasAuthorship W2034207391A5087187658 @default.
• W2034207391 hasBestOaLocation W20342073911 @default.
• W2034207391 hasConcept C104317684 @default.
• W2034207391 hasConcept C127561419 @default.
• W2034207391 hasConcept C147483822 @default.
• W2034207391 hasConcept C147969180 @default.
• W2034207391 hasConcept C154317977 @default.
• W2034207391 hasConcept C159047783 @default.
• W2034207391 hasConcept C167672396 @default.
• W2034207391 hasConcept C170627219 @default.
• W2034207391 hasConcept C188280979 @default.
• W2034207391 hasConcept C202751555 @default.
• W2034207391 hasConcept C203014093 @default.
• W2034207391 hasConcept C207936829 @default.
• W2034207391 hasConcept C54355233 @default.
• W2034207391 hasConcept C86803240 @default.
• W2034207391 hasConcept C8891405 @default.
• W2034207391 hasConceptScore W2034207391C104317684 @default.
• W2034207391 hasConceptScore W2034207391C127561419 @default.
• W2034207391 hasConceptScore W2034207391C147483822 @default.
• W2034207391 hasConceptScore W2034207391C147969180 @default.
• W2034207391 hasConceptScore W2034207391C154317977 @default.

• next