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- W2034208256 abstract "ConclusionsThis study reveals that the penicillin lymph level is more prolonged than the blood level. The appearance of penicillin in the blood earlier than in the lymph suggests that the absorption of penicillin takes place through the blood capillaries. It seems to be a regular occurrence that penicillin, after its passage from the blood into the lymphatic system and into the tissues, is retained longer in the last two.That there is a definite accumulation of penicillin in the organs, particularly following repository injection, is clearly demonstrated by our data on dogs and further substantiated by other rat experiments.4 The elimination through the lymphatics of this penicillin accumulated in the organs might be responsible for the prolongation of the lymph levels.The penicillin found in the thoracic duct reaches the blood stream where, following its greater dilution, it becomes bacteriologically undetectable. In all probability, this undetectable penicillin is concentrated in the kidneys and then re..." @default.
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- W2034208256 date "1948-05-01" @default.
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- W2034208256 title "Fate and Distribution of Penicillin in the Body. I. Circulation of Penicillin in the Lymph." @default.
- W2034208256 doi "https://doi.org/10.3181/00379727-68-16382" @default.
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