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• W2034208711 endingPage "5485" @default.
• W2034208711 startingPage "5480" @default.
• W2034208711 abstract "As an attempt to quantitatively analyze the physiopsychological effects elicited by odorants, white blood cells and gene expression were profiled in the whole blood of the rats exposed to (R)-(-)-linalool during restraint stress for 2 h. In neutrophils and lymphocytes, significant changes caused by the restraint were repressed by their exposure to the odorant. This indicates that inhalation attenuates stress-induced changes. Significant changes on the stress-induced variations were induced by inhalation in 115 gene expression levels. Of those, 109 genes were down-regulated, whereas the remaining 6 were up-regulated. These findings show that (R)-(-)-linalool inhalation represses stress-induced effects on the profiles of both blood cells and gene expression. Furthermore, these results suggest the possibility that the odorant-induced effects can be quantitatively evaluated by analyzing the profiles of blood cells and gene expression." @default.
• W2034208711 created "2016-06-24" @default.
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• W2034208711 date "2009-05-20" @default.
• W2034208711 modified "2023-10-03" @default.
• W2034208711 title "Stress Repression in Restrained Rats by (<i>R</i>)-(−)-Linalool Inhalation and Gene Expression Profiling of Their Whole Blood Cells" @default.
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• W2034208711 doi "https://doi.org/10.1021/jf900420g" @default.
• W2034208711 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19456160" @default.
• W2034208711 hasPublicationYear "2009" @default.
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