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• W2034221979 abstract "Lipid microparticles (lipospheres) loaded with butyl methoxydibenzoylmethane (BMDBM), a widely used UV-A sunscreen agent, were prepared by melt technique and evaluated for skin permeation both in vivo, by tape stripping method, and in vitro, by a flow-through diffusion chamber. Following in vivo human skin application of an O/W emulsion containing 2% of BMDBM loaded in lipospheres, 15% of the applied sunscreen accumulated in the uppermost layers of the stratum corneum without remarkably modifying the skin permeation of the unencapsulated sunscreen. These results were found to be predicted by an in vitro methodology involving the diffusion of BMDBM through a lipophilized synthetic membrane into a hydrophilic receptor phase, simulating the viable epidermis better than an ethanolic receptor phase." @default.
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• W2034221979 date "2007-10-11" @default.
• W2034221979 modified "2023-09-26" @default.
• W2034221979 title "In vivo and in vitro Skin Permeation of Butyl Methoxydibenzoylmethane from Lipospheres" @default.
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• W2034221979 doi "https://doi.org/10.1159/000109656" @default.
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