Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034222431> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2034222431 endingPage "699" @default.
- W2034222431 startingPage "695" @default.
- W2034222431 abstract "The regulation of the hypothalamo-pituitary-adrenal (HPA) axis in the operative and perioperative period of major surgical procedures is necessary for successful adaption to surgical stress. We report evidence on an altered response of HPA axis regulation in patients who underwent coronary artery bypass grafting (CABG) surgery. Plasma levels of adrenocorticotropin (ACTH), β-endorphin, and cortisol were determined with radioimmune assay in 50 males for elective CABG surgery. The patients received general anesthesia using a balanced technique with sufentanil, isoflurane, and midazolam. Pre- and intraoperatively, there was no significant increase in plasma cortisol, ACTH, and β-endorphin levels. On the evening of surgery, all plasma hormone levels were increased. On the evening of the first and second postoperative day, plasma ACTH and β-endorphin levels returned to the preoperative baseline values. During the same time interval, plasma cortisol levels were significantly elevated and remained high until the end of the study period (p < 0.001). Our results indicate an altered regulation of the HPA axis in the postoperative period of patients after CABG surgery, as they are compatible with similar results in patients after major abdominal surgery, burned patients, and critically ill patients. Therefore, it is assumed that the finding of a postoperative dissociation between ACTH and cortisol is a result of the severity of perioperative adaptive mechanisms rather than of the specific conditions related to cardiac surgery." @default.
- W2034222431 created "2016-06-24" @default.
- W2034222431 creator A5024110158 @default.
- W2034222431 creator A5064979704 @default.
- W2034222431 date "1997-11-01" @default.
- W2034222431 modified "2023-09-27" @default.
- W2034222431 title "Postoperative dissociation of blood levels of cortisol and adrenocorticotropin after coronary artery bypass grafting surgery" @default.
- W2034222431 cites W1966344978 @default.
- W2034222431 cites W2004973778 @default.
- W2034222431 cites W2006131635 @default.
- W2034222431 cites W2031149131 @default.
- W2034222431 cites W2084683053 @default.
- W2034222431 cites W2088983034 @default.
- W2034222431 cites W2089906970 @default.
- W2034222431 cites W2090004426 @default.
- W2034222431 cites W2128631462 @default.
- W2034222431 doi "https://doi.org/10.1016/s0039-128x(97)00069-x" @default.
- W2034222431 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9366007" @default.
- W2034222431 hasPublicationYear "1997" @default.
- W2034222431 type Work @default.
- W2034222431 sameAs 2034222431 @default.
- W2034222431 citedByCount "48" @default.
- W2034222431 countsByYear W20342224312013 @default.
- W2034222431 countsByYear W20342224312015 @default.
- W2034222431 countsByYear W20342224312016 @default.
- W2034222431 countsByYear W20342224312017 @default.
- W2034222431 countsByYear W20342224312018 @default.
- W2034222431 countsByYear W20342224312019 @default.
- W2034222431 countsByYear W20342224312020 @default.
- W2034222431 countsByYear W20342224312021 @default.
- W2034222431 crossrefType "journal-article" @default.
- W2034222431 hasAuthorship W2034222431A5024110158 @default.
- W2034222431 hasAuthorship W2034222431A5064979704 @default.
- W2034222431 hasConcept C121332964 @default.
- W2034222431 hasConcept C126322002 @default.
- W2034222431 hasConcept C1276947 @default.
- W2034222431 hasConcept C141071460 @default.
- W2034222431 hasConcept C2776098842 @default.
- W2034222431 hasConcept C2776359302 @default.
- W2034222431 hasConcept C2776476923 @default.
- W2034222431 hasConcept C2776719974 @default.
- W2034222431 hasConcept C2776820930 @default.
- W2034222431 hasConcept C2778709874 @default.
- W2034222431 hasConcept C2778789114 @default.
- W2034222431 hasConcept C2780120127 @default.
- W2034222431 hasConcept C3017915907 @default.
- W2034222431 hasConcept C31174226 @default.
- W2034222431 hasConcept C42219234 @default.
- W2034222431 hasConcept C71315377 @default.
- W2034222431 hasConcept C71924100 @default.
- W2034222431 hasConceptScore W2034222431C121332964 @default.
- W2034222431 hasConceptScore W2034222431C126322002 @default.
- W2034222431 hasConceptScore W2034222431C1276947 @default.
- W2034222431 hasConceptScore W2034222431C141071460 @default.
- W2034222431 hasConceptScore W2034222431C2776098842 @default.
- W2034222431 hasConceptScore W2034222431C2776359302 @default.
- W2034222431 hasConceptScore W2034222431C2776476923 @default.
- W2034222431 hasConceptScore W2034222431C2776719974 @default.
- W2034222431 hasConceptScore W2034222431C2776820930 @default.
- W2034222431 hasConceptScore W2034222431C2778709874 @default.
- W2034222431 hasConceptScore W2034222431C2778789114 @default.
- W2034222431 hasConceptScore W2034222431C2780120127 @default.
- W2034222431 hasConceptScore W2034222431C3017915907 @default.
- W2034222431 hasConceptScore W2034222431C31174226 @default.
- W2034222431 hasConceptScore W2034222431C42219234 @default.
- W2034222431 hasConceptScore W2034222431C71315377 @default.
- W2034222431 hasConceptScore W2034222431C71924100 @default.
- W2034222431 hasIssue "11" @default.
- W2034222431 hasLocation W20342224311 @default.
- W2034222431 hasLocation W20342224312 @default.
- W2034222431 hasOpenAccess W2034222431 @default.
- W2034222431 hasPrimaryLocation W20342224311 @default.
- W2034222431 hasRelatedWork W1580905093 @default.
- W2034222431 hasRelatedWork W2016346382 @default.
- W2034222431 hasRelatedWork W2075409372 @default.
- W2034222431 hasRelatedWork W2098045683 @default.
- W2034222431 hasRelatedWork W2124511477 @default.
- W2034222431 hasRelatedWork W2349704290 @default.
- W2034222431 hasRelatedWork W2353283287 @default.
- W2034222431 hasRelatedWork W2356860550 @default.
- W2034222431 hasRelatedWork W2392407047 @default.
- W2034222431 hasRelatedWork W3151426539 @default.
- W2034222431 hasVolume "62" @default.
- W2034222431 isParatext "false" @default.
- W2034222431 isRetracted "false" @default.
- W2034222431 magId "2034222431" @default.
- W2034222431 workType "article" @default.