FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034223596> ?p ?o ?g. }

• W2034223596 endingPage "545" @default.
• W2034223596 startingPage "540" @default.
• W2034223596 abstract "We here report a simple assay system for DNA methyltransferase (DNMT) inhibitors based on the HBx-induced DNA methylation of E-cadherin. A stable cell line named G1 was generated by co-transfecting E-cadherin luciferase reporter and HBx-expression plasmid into HepG2 cells. Treatment of G1 cells with DNMT inhibitors, 5-azacytidine, 5-aza-2′-deoxycytidine, and procainamaid, dose-dependently inhibited DNA methylation of E-cadherin promoter in the reporter, resulting in up-regulation of luciferase levels and its enzyme activity. Treatment with all-trans retinoic acid that is known to inhibit DNMT expression, also induced similar effects. Our system can be useful for development of epi-drugs targeting DNA methylation in malignancies." @default.
• W2034223596 created "2016-06-24" @default.
• W2034223596 creator A5006285346 @default.
• W2034223596 creator A5015514278 @default.
• W2034223596 creator A5046070308 @default.
• W2034223596 creator A5074143108 @default.
• W2034223596 date "2013-08-01" @default.
• W2034223596 modified "2023-09-27" @default.
• W2034223596 title "DNA methyltransferase inhibitor assay system based on the HBx-induced DNA methylation of E-cadherin" @default.
• W2034223596 cites W1519745137 @default.
• W2034223596 cites W1976118924 @default.
• W2034223596 cites W1980514257 @default.
• W2034223596 cites W1983440773 @default.
• W2034223596 cites W1994465394 @default.
• W2034223596 cites W1998149374 @default.
• W2034223596 cites W2002080898 @default.
• W2034223596 cites W2013154874 @default.
• W2034223596 cites W2013250198 @default.
• W2034223596 cites W2017515560 @default.
• W2034223596 cites W2018902035 @default.
• W2034223596 cites W2022915997 @default.
• W2034223596 cites W2026584824 @default.
• W2034223596 cites W2033408643 @default.
• W2034223596 cites W2040185193 @default.
• W2034223596 cites W2041674913 @default.
• W2034223596 cites W2041690843 @default.
• W2034223596 cites W2046100841 @default.
• W2034223596 cites W2055770867 @default.
• W2034223596 cites W2067837358 @default.
• W2034223596 cites W2073580257 @default.
• W2034223596 cites W2084940240 @default.
• W2034223596 cites W2086492419 @default.
• W2034223596 cites W2106584820 @default.
• W2034223596 cites W2106833395 @default.
• W2034223596 cites W2107038650 @default.
• W2034223596 cites W2124418078 @default.
• W2034223596 cites W2130516508 @default.
• W2034223596 cites W2135231304 @default.
• W2034223596 cites W2142139678 @default.
• W2034223596 cites W2146935613 @default.
• W2034223596 cites W4230479687 @default.
• W2034223596 cites W4378718562 @default.
• W2034223596 doi "https://doi.org/10.1016/j.bbrc.2013.07.094" @default.
• W2034223596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23906757" @default.
• W2034223596 hasPublicationYear "2013" @default.
• W2034223596 type Work @default.
• W2034223596 sameAs 2034223596 @default.
• W2034223596 citedByCount "5" @default.
• W2034223596 countsByYear W20342235962015 @default.
• W2034223596 countsByYear W20342235962019 @default.
• W2034223596 countsByYear W20342235962021 @default.
• W2034223596 countsByYear W20342235962022 @default.
• W2034223596 countsByYear W20342235962023 @default.
• W2034223596 crossrefType "journal-article" @default.
• W2034223596 hasAuthorship W2034223596A5006285346 @default.
• W2034223596 hasAuthorship W2034223596A5015514278 @default.
• W2034223596 hasAuthorship W2034223596A5046070308 @default.
• W2034223596 hasAuthorship W2034223596A5074143108 @default.
• W2034223596 hasConcept C104317684 @default.
• W2034223596 hasConcept C111335760 @default.
• W2034223596 hasConcept C150194340 @default.
• W2034223596 hasConcept C153911025 @default.
• W2034223596 hasConcept C185592680 @default.
• W2034223596 hasConcept C190727270 @default.
• W2034223596 hasConcept C22744801 @default.
• W2034223596 hasConcept C2779979206 @default.
• W2034223596 hasConcept C33288867 @default.
• W2034223596 hasConcept C41091548 @default.
• W2034223596 hasConcept C54009773 @default.
• W2034223596 hasConcept C552990157 @default.
• W2034223596 hasConcept C55493867 @default.
• W2034223596 hasConcept C67567795 @default.
• W2034223596 hasConcept C86803240 @default.
• W2034223596 hasConcept C91965660 @default.
• W2034223596 hasConceptScore W2034223596C104317684 @default.
• W2034223596 hasConceptScore W2034223596C111335760 @default.
• W2034223596 hasConceptScore W2034223596C150194340 @default.
• W2034223596 hasConceptScore W2034223596C153911025 @default.
• W2034223596 hasConceptScore W2034223596C185592680 @default.
• W2034223596 hasConceptScore W2034223596C190727270 @default.
• W2034223596 hasConceptScore W2034223596C22744801 @default.
• W2034223596 hasConceptScore W2034223596C2779979206 @default.
• W2034223596 hasConceptScore W2034223596C33288867 @default.
• W2034223596 hasConceptScore W2034223596C41091548 @default.
• W2034223596 hasConceptScore W2034223596C54009773 @default.
• W2034223596 hasConceptScore W2034223596C552990157 @default.
• W2034223596 hasConceptScore W2034223596C55493867 @default.
• W2034223596 hasConceptScore W2034223596C67567795 @default.
• W2034223596 hasConceptScore W2034223596C86803240 @default.
• W2034223596 hasConceptScore W2034223596C91965660 @default.
• W2034223596 hasIssue "3" @default.
• W2034223596 hasLocation W20342235961 @default.
• W2034223596 hasLocation W20342235962 @default.
• W2034223596 hasOpenAccess W2034223596 @default.
• W2034223596 hasPrimaryLocation W20342235961 @default.
• W2034223596 hasRelatedWork W1534737270 @default.
• W2034223596 hasRelatedWork W1983166726 @default.
• W2034223596 hasRelatedWork W2089764511 @default.

• next