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- W203422437 abstract "The Burden of Avian Influenza Viruses in Community Ponds in California by Zin Htway MBA, Western Governor’s University, 2011 BS, California State University Dominguez Hills, 1992 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Public Health Walden University December 2014 Abstract Emerging influenza viruses continue to challenge public health. The problem is public health science professionals have been battling emerging human influenza diseases with tactile and reactionary methods because there is a lack of knowledge and data at the human-animal interface. This research was a baseline study of the proportion of influenza A virus (IAV) in urban and rural communities in California. The population was artificialEmerging influenza viruses continue to challenge public health. The problem is public health science professionals have been battling emerging human influenza diseases with tactile and reactionary methods because there is a lack of knowledge and data at the human-animal interface. This research was a baseline study of the proportion of influenza A virus (IAV) in urban and rural communities in California. The population was artificial recirculating water ponds in the geographic locations of rural and urban Californian communities. Surface water samples [N = 182] were collected from artificial recirculating ponds in California. Positivity for IAV was verified by real time RT-PCR, MDCK cells for virus infectivity, nucleotide sequencing of the RNA genome, and phylogenic analysis of IAV H5N1 strains. The proportion of IAV in rural and urban ponds favored the greater burden of IAV in urban ponds over rural ponds. The presence of waterfowl and IAV M gene sequence positivity were found not to be significantly related. The geochemical properties—pH, salinity, and water temperature at time of collection—were not predictors of IAV infectivity. This baseline research study validated these water ponds as resource sites for IAV surveillance and monitoring. The social change implications of this study can be recognized at the national and international levels, to the population level, and to the individual level by providing geospatial analysis and spatial-temporal data for IAV surveillance, initiating biosecurity measures to protect poultry industries in the United States and Brazil, and contributing to the current IAV strain library. Contributions to the IAV strain library may be used to develop vaccines against human pandemics. The Burden of Avian Influenza Viruses in Community Ponds in California by Zin Htway MBA, Western Governor’s University, 2011 BS, California State University Dominguez Hills, 1992 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Public Health Walden University December 2014 Dedication I dedicate this dissertation to my loving wife, Christi, for supporting me each day as I traveled this journey. I also dedicate this dissertation to our three children, Emily, Oliver, and Gabrielle, for giving me a purpose to complete this journey. And lastly, I dedicate this dissertation to our parents, for providing the encouragement I needed and for just being proud of me all the way through. Acknowledgments I wish to acknowledge the dissertation committee. I am very thankful to Dr. Richard Jimenez for accepting to be chair of the dissertation committee and for persevering as my adviser. His support and guidance was fundamental to my completion and success. I am very thankful to Dr. Latoya Johnson for insisting that my work be of the highest quality. I am thankful to Dr. Rodney Bowden for giving me motivating praise at the right times throughout my PhD journey. I am also thankful to the California State University Channel Islands Biology/Natural Sciences Program for providing me with a working research laboratory environment. To all my friends, colleagues, students, teachers, and advisers who guided and supported me along this journey, I cannot express my gratitude and deep appreciation fully. I am especially grateful to Catherine Hutchinson, who generously shared her meticulous research and insights that supported and expanded my own work." @default.
- W203422437 created "2016-06-24" @default.
- W203422437 creator A5017048302 @default.
- W203422437 date "2014-01-01" @default.
- W203422437 modified "2023-09-27" @default.
- W203422437 title "The Burden of Avian Influenza Viruses in Community Ponds in California" @default.
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