Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034233074> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2034233074 endingPage "438" @default.
- W2034233074 startingPage "429" @default.
- W2034233074 abstract "[14C]-Labeled {[trans-(8 β)]-6-methyl-1-(1-methylethyl)ergoline-8-carboxylic acid, 4-methoxycyclohexyl ester (Z)-2-butenedioate (1:1)} (LY281067) (10) was synthesized from unlabeled 6-methyl-1-(1-methylethyl)ergoline-8-carboxylic acid (2). The [14C] label was introduced into the carboxyl group attached to the 8 position of the ergoline nucleus. This site is stable to metabolism. The synthesis involves removal of the unlabeled carboxyl group from 2 and subsequent reinsertion of a [14C]-labeled carboxyl group into the same position. The radiolabel is not introduced until near the end of the synthesis which allows for ease of handling and scale-up of intermediates." @default.
- W2034233074 created "2016-06-24" @default.
- W2034233074 creator A5020623335 @default.
- W2034233074 creator A5037923455 @default.
- W2034233074 creator A5008229875 @default.
- W2034233074 date "1988-04-01" @default.
- W2034233074 modified "2023-09-24" @default.
- W2034233074 title "[14C] - radiolabeling of {[trans-(8β)]-6-methyl-1-(1-methylethyl) ergoline-8-carboxylic acid, 4-methoxycyclohexyl ester (Z)-2-butenedioate [(1:1)]. A potent and selective 5ht2-receptor antagonist" @default.
- W2034233074 cites W2016270509 @default.
- W2034233074 cites W2037083014 @default.
- W2034233074 cites W2117827358 @default.
- W2034233074 cites W2165010013 @default.
- W2034233074 doi "https://doi.org/10.1002/jlcr.2580250409" @default.
- W2034233074 hasPublicationYear "1988" @default.
- W2034233074 type Work @default.
- W2034233074 sameAs 2034233074 @default.
- W2034233074 citedByCount "4" @default.
- W2034233074 countsByYear W20342330742018 @default.
- W2034233074 crossrefType "journal-article" @default.
- W2034233074 hasAuthorship W2034233074A5008229875 @default.
- W2034233074 hasAuthorship W2034233074A5020623335 @default.
- W2034233074 hasAuthorship W2034233074A5037923455 @default.
- W2034233074 hasConcept C114373084 @default.
- W2034233074 hasConcept C170493617 @default.
- W2034233074 hasConcept C178790620 @default.
- W2034233074 hasConcept C185592680 @default.
- W2034233074 hasConcept C202751555 @default.
- W2034233074 hasConcept C2776885963 @default.
- W2034233074 hasConcept C2778565081 @default.
- W2034233074 hasConcept C2779074116 @default.
- W2034233074 hasConcept C2781311116 @default.
- W2034233074 hasConcept C55493867 @default.
- W2034233074 hasConcept C62231903 @default.
- W2034233074 hasConcept C71240020 @default.
- W2034233074 hasConceptScore W2034233074C114373084 @default.
- W2034233074 hasConceptScore W2034233074C170493617 @default.
- W2034233074 hasConceptScore W2034233074C178790620 @default.
- W2034233074 hasConceptScore W2034233074C185592680 @default.
- W2034233074 hasConceptScore W2034233074C202751555 @default.
- W2034233074 hasConceptScore W2034233074C2776885963 @default.
- W2034233074 hasConceptScore W2034233074C2778565081 @default.
- W2034233074 hasConceptScore W2034233074C2779074116 @default.
- W2034233074 hasConceptScore W2034233074C2781311116 @default.
- W2034233074 hasConceptScore W2034233074C55493867 @default.
- W2034233074 hasConceptScore W2034233074C62231903 @default.
- W2034233074 hasConceptScore W2034233074C71240020 @default.
- W2034233074 hasIssue "4" @default.
- W2034233074 hasLocation W20342330741 @default.
- W2034233074 hasOpenAccess W2034233074 @default.
- W2034233074 hasPrimaryLocation W20342330741 @default.
- W2034233074 hasRelatedWork W1968206883 @default.
- W2034233074 hasRelatedWork W1968955400 @default.
- W2034233074 hasRelatedWork W1971788857 @default.
- W2034233074 hasRelatedWork W1995567630 @default.
- W2034233074 hasRelatedWork W2010672805 @default.
- W2034233074 hasRelatedWork W2021874346 @default.
- W2034233074 hasRelatedWork W2074596941 @default.
- W2034233074 hasRelatedWork W2110912515 @default.
- W2034233074 hasRelatedWork W2952640555 @default.
- W2034233074 hasRelatedWork W4240462900 @default.
- W2034233074 hasVolume "25" @default.
- W2034233074 isParatext "false" @default.
- W2034233074 isRetracted "false" @default.
- W2034233074 magId "2034233074" @default.
- W2034233074 workType "article" @default.