Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034235722> ?p ?o ?g. }
- W2034235722 endingPage "197" @default.
- W2034235722 startingPage "188" @default.
- W2034235722 abstract "Entamoeba histolytica presents the evolutionarily conserved multidrug-resistance (MDR) phenotype, discovered in mammalian cells. MDR cells overexpress the membrane P-glycoprotein, which excludes unrelated drugs from the cytoplasm. E. histolytica mutants exhibit cross-resistance to unrelated drugs, which are pumped out from the cytoplasm. In drug-resistant trophozoites, the constitutively expressed EhPg1 gene appears to be up-regulated by a C/EBP-like factor and a multiprotein complex that were not found in drug-sensitive trophozoites. The drug-induced EhPgp5 gene, on the other hand, appears to be up-regulated by AP-1 and HOX factors. Here we review the main physiological and molecular facts of the MDR phenotype in E. histolytica." @default.
- W2034235722 created "2016-06-24" @default.
- W2034235722 creator A5021838579 @default.
- W2034235722 creator A5055280434 @default.
- W2034235722 creator A5076368629 @default.
- W2034235722 date "1999-06-01" @default.
- W2034235722 modified "2023-09-27" @default.
- W2034235722 title "Physiology and molecular genetics of multidrug resistance in Entamoeba histolytica" @default.
- W2034235722 cites W1485008430 @default.
- W2034235722 cites W1487564761 @default.
- W2034235722 cites W1489042738 @default.
- W2034235722 cites W1502426706 @default.
- W2034235722 cites W1515117525 @default.
- W2034235722 cites W1539233028 @default.
- W2034235722 cites W1547452419 @default.
- W2034235722 cites W1596279668 @default.
- W2034235722 cites W1660272883 @default.
- W2034235722 cites W1716367672 @default.
- W2034235722 cites W1768645045 @default.
- W2034235722 cites W1923579966 @default.
- W2034235722 cites W1966124517 @default.
- W2034235722 cites W1971950332 @default.
- W2034235722 cites W1975282446 @default.
- W2034235722 cites W1977443669 @default.
- W2034235722 cites W1977565325 @default.
- W2034235722 cites W1978033522 @default.
- W2034235722 cites W1978927028 @default.
- W2034235722 cites W1980206379 @default.
- W2034235722 cites W1982436440 @default.
- W2034235722 cites W1982631354 @default.
- W2034235722 cites W1984979458 @default.
- W2034235722 cites W1988408916 @default.
- W2034235722 cites W1990380859 @default.
- W2034235722 cites W1993252319 @default.
- W2034235722 cites W1997366474 @default.
- W2034235722 cites W2001692561 @default.
- W2034235722 cites W2001882472 @default.
- W2034235722 cites W2009979935 @default.
- W2034235722 cites W2012120642 @default.
- W2034235722 cites W2013540958 @default.
- W2034235722 cites W2014593961 @default.
- W2034235722 cites W2015736441 @default.
- W2034235722 cites W2016045984 @default.
- W2034235722 cites W2026526086 @default.
- W2034235722 cites W2026545794 @default.
- W2034235722 cites W2027708100 @default.
- W2034235722 cites W2028533496 @default.
- W2034235722 cites W2032011458 @default.
- W2034235722 cites W2037086732 @default.
- W2034235722 cites W2037455648 @default.
- W2034235722 cites W2037621239 @default.
- W2034235722 cites W2041773597 @default.
- W2034235722 cites W2044447608 @default.
- W2034235722 cites W2048356148 @default.
- W2034235722 cites W2049354257 @default.
- W2034235722 cites W2052663514 @default.
- W2034235722 cites W2053132846 @default.
- W2034235722 cites W2057969349 @default.
- W2034235722 cites W2062916685 @default.
- W2034235722 cites W2072444095 @default.
- W2034235722 cites W2074196529 @default.
- W2034235722 cites W2074463981 @default.
- W2034235722 cites W2075026023 @default.
- W2034235722 cites W2075243485 @default.
- W2034235722 cites W2081552804 @default.
- W2034235722 cites W2084317060 @default.
- W2034235722 cites W2086430542 @default.
- W2034235722 cites W2088575414 @default.
- W2034235722 cites W2092396319 @default.
- W2034235722 cites W2118234018 @default.
- W2034235722 cites W2133067039 @default.
- W2034235722 cites W2134548140 @default.
- W2034235722 cites W2153712534 @default.
- W2034235722 cites W2154504118 @default.
- W2034235722 cites W2160778580 @default.
- W2034235722 cites W2161709854 @default.
- W2034235722 cites W2166628294 @default.
- W2034235722 cites W2168095256 @default.
- W2034235722 cites W2168519589 @default.
- W2034235722 cites W2182051052 @default.
- W2034235722 cites W2335591625 @default.
- W2034235722 cites W4230998375 @default.
- W2034235722 cites W4233799830 @default.
- W2034235722 cites W4234511678 @default.
- W2034235722 cites W4244823109 @default.
- W2034235722 doi "https://doi.org/10.1054/drup.1999.0087" @default.
- W2034235722 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11504490" @default.
- W2034235722 hasPublicationYear "1999" @default.
- W2034235722 type Work @default.
- W2034235722 sameAs 2034235722 @default.
- W2034235722 citedByCount "10" @default.
- W2034235722 countsByYear W20342357222020 @default.
- W2034235722 countsByYear W20342357222023 @default.
- W2034235722 crossrefType "journal-article" @default.
- W2034235722 hasAuthorship W2034235722A5021838579 @default.
- W2034235722 hasAuthorship W2034235722A5055280434 @default.
- W2034235722 hasAuthorship W2034235722A5076368629 @default.
- W2034235722 hasConcept C104317684 @default.