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- W2034235936 abstract "Transcription in heterochromatin seems to be an oxymoron--surely the 'silenced' form of chromatin should not be transcribed. But there have been frequent reports of low-level transcription in heterochromatic regions, and several hundred genes are found in these regions in Drosophila. Most strikingly, recent investigations implicate RNA interference mechanisms in targeting and maintaining heterochromatin, and these mechanisms are inherently dependent on transcription. Silencing of chromatin might involve trans-acting sources of the crucial small RNAs that carry out RNA interference, but in some cases, transcription of the region to be silenced seems to be required--an apparent contradiction." @default.
- W2034235936 created "2016-06-24" @default.
- W2034235936 creator A5020713009 @default.
- W2034235936 creator A5086056549 @default.
- W2034235936 date "2007-05-01" @default.
- W2034235936 modified "2023-10-14" @default.
- W2034235936 title "Transcription and RNA interference in the formation of heterochromatin" @default.
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- W2034235936 doi "https://doi.org/10.1038/nature05914" @default.
- W2034235936 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2950806" @default.
- W2034235936 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17522672" @default.
- W2034235936 hasPublicationYear "2007" @default.
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