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- W2034237889 abstract "Large numbers of patients present with abnormal liver function tests, but only a minority have significant liver disease. Physical examination may help in identifying patients with significant liver disease and in selecting patients who may require liver biopsy. Over a number of years we noted that a palpable liver in the epigastrium was common in patients with cirrhosis. The aim of this study was to evaluate this clinical sign in a cohort of patients undergoing liver biopsy.We prospectively studied 138 consecutive patients undergoing liver biopsy in a university teaching hospital. The main outcome measure was liver fibrosis measured using the standard METAVIR scoring system.Thirty-eight patients had no fibrosis on biopsy, 11 patients had grade 1, eight patients had grade 2, 14 patients had grade 3 and 42 patients had grade 4 (cirrhosis). Palpable epigastric liver had a sensitivity of 86% and a specificity of 67% for the diagnosis of cirrhosis in this cohort.We suggest that a palpable liver in the epigastrium is a useful physical sign of cirrhosis in clinical practice." @default.
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- W2034237889 date "2004-12-01" @default.
- W2034237889 modified "2023-10-16" @default.
- W2034237889 title "Palpable epigastric liver as a physical sign of cirrhosis" @default.
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- W2034237889 doi "https://doi.org/10.1097/00042737-200412000-00016" @default.
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