Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034239774> ?p ?o ?g. }
- W2034239774 endingPage "58" @default.
- W2034239774 startingPage "50" @default.
- W2034239774 abstract "Several diseases can lead to opacification of cornea requiring transplantation of donor tissue to restore vision. In this context, transparent collagen I fibrillated matrices have been synthesized at 15, 30, 60 and 90 mg/mL. The matrices were evaluated for fibril organizations, transparency, mechanical properties and ability to support corneal epithelial cell culture. The best results were obtained with 90 mg/mL scaffolds. At this concentration, the fibril organization presented some similarities to that found in corneal stroma. Matrices had a mean Young's modulus of 570 kPa and acellular scaffolds had a transparency of 87% in the 380-780 nm wavelength range. Human corneal epithelial cells successfully colonized the surface of the scaffolds and generated an epithelium with characteristics of corneal epithelial cells (i.e. expression of cytokeratin 3 and presence of desmosomes) and maintenance of stemness during culture (i.e. expression of ΔNp63α and formation of holoclones in colony formation assay). Presence of cultured epithelium on the matrices was associated with increased transparency (89%)." @default.
- W2034239774 created "2016-06-24" @default.
- W2034239774 creator A5001656521 @default.
- W2034239774 creator A5002336596 @default.
- W2034239774 creator A5003136625 @default.
- W2034239774 creator A5027079635 @default.
- W2034239774 creator A5033986039 @default.
- W2034239774 creator A5057779805 @default.
- W2034239774 creator A5082775129 @default.
- W2034239774 creator A5084638816 @default.
- W2034239774 date "2015-08-01" @default.
- W2034239774 modified "2023-09-26" @default.
- W2034239774 title "Development of human corneal epithelium on organized fibrillated transparent collagen matrices synthesized at high concentration" @default.
- W2034239774 cites W1982810141 @default.
- W2034239774 cites W1985437381 @default.
- W2034239774 cites W1987195751 @default.
- W2034239774 cites W1990552062 @default.
- W2034239774 cites W2003322621 @default.
- W2034239774 cites W2008128553 @default.
- W2034239774 cites W2025339018 @default.
- W2034239774 cites W2028727094 @default.
- W2034239774 cites W2031396751 @default.
- W2034239774 cites W2034126085 @default.
- W2034239774 cites W2036019924 @default.
- W2034239774 cites W2038723174 @default.
- W2034239774 cites W2039040959 @default.
- W2034239774 cites W2042297859 @default.
- W2034239774 cites W2043983669 @default.
- W2034239774 cites W2044229000 @default.
- W2034239774 cites W2049300022 @default.
- W2034239774 cites W2051018861 @default.
- W2034239774 cites W2054293005 @default.
- W2034239774 cites W2054635074 @default.
- W2034239774 cites W2054710058 @default.
- W2034239774 cites W2056796251 @default.
- W2034239774 cites W2058070608 @default.
- W2034239774 cites W2066939743 @default.
- W2034239774 cites W2069225582 @default.
- W2034239774 cites W2070136044 @default.
- W2034239774 cites W2072281160 @default.
- W2034239774 cites W2073826009 @default.
- W2034239774 cites W2082369307 @default.
- W2034239774 cites W2084168776 @default.
- W2034239774 cites W2112980158 @default.
- W2034239774 cites W2125413204 @default.
- W2034239774 cites W2128076390 @default.
- W2034239774 cites W2132070523 @default.
- W2034239774 cites W2134208433 @default.
- W2034239774 cites W2137942762 @default.
- W2034239774 cites W2152635187 @default.
- W2034239774 cites W2162140802 @default.
- W2034239774 doi "https://doi.org/10.1016/j.actbio.2015.04.018" @default.
- W2034239774 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25931016" @default.
- W2034239774 hasPublicationYear "2015" @default.
- W2034239774 type Work @default.
- W2034239774 sameAs 2034239774 @default.
- W2034239774 citedByCount "27" @default.
- W2034239774 countsByYear W20342397742016 @default.
- W2034239774 countsByYear W20342397742017 @default.
- W2034239774 countsByYear W20342397742018 @default.
- W2034239774 countsByYear W20342397742019 @default.
- W2034239774 countsByYear W20342397742020 @default.
- W2034239774 countsByYear W20342397742021 @default.
- W2034239774 countsByYear W20342397742022 @default.
- W2034239774 countsByYear W20342397742023 @default.
- W2034239774 crossrefType "journal-article" @default.
- W2034239774 hasAuthorship W2034239774A5001656521 @default.
- W2034239774 hasAuthorship W2034239774A5002336596 @default.
- W2034239774 hasAuthorship W2034239774A5003136625 @default.
- W2034239774 hasAuthorship W2034239774A5027079635 @default.
- W2034239774 hasAuthorship W2034239774A5033986039 @default.
- W2034239774 hasAuthorship W2034239774A5057779805 @default.
- W2034239774 hasAuthorship W2034239774A5082775129 @default.
- W2034239774 hasAuthorship W2034239774A5084638816 @default.
- W2034239774 hasConcept C118487528 @default.
- W2034239774 hasConcept C136229726 @default.
- W2034239774 hasConcept C142724271 @default.
- W2034239774 hasConcept C151730666 @default.
- W2034239774 hasConcept C17744445 @default.
- W2034239774 hasConcept C192562407 @default.
- W2034239774 hasConcept C199539241 @default.
- W2034239774 hasConcept C204232928 @default.
- W2034239774 hasConcept C2776882836 @default.
- W2034239774 hasConcept C2779012181 @default.
- W2034239774 hasConcept C2779257441 @default.
- W2034239774 hasConcept C2779343474 @default.
- W2034239774 hasConcept C2780233690 @default.
- W2034239774 hasConcept C49892992 @default.
- W2034239774 hasConcept C52124034 @default.
- W2034239774 hasConcept C529295009 @default.
- W2034239774 hasConcept C71924100 @default.
- W2034239774 hasConcept C86803240 @default.
- W2034239774 hasConcept C95444343 @default.
- W2034239774 hasConceptScore W2034239774C118487528 @default.
- W2034239774 hasConceptScore W2034239774C136229726 @default.
- W2034239774 hasConceptScore W2034239774C142724271 @default.
- W2034239774 hasConceptScore W2034239774C151730666 @default.
- W2034239774 hasConceptScore W2034239774C17744445 @default.