FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034243341> ?p ?o ?g. }

• W2034243341 endingPage "335" @default.
• W2034243341 startingPage "329" @default.
• W2034243341 abstract "Objective To assess the effects of bazedoxifene/conjugated estrogens (BZA/CE) on sleep parameters and health-related quality of life (HR-QOL). Methods This was a 12-week, multicenter, double-blind, placebo-controlled phase 3 study. Postmenopausal women with an intact uterus and experiencing ≥7 moderate-to-severe hot flushes daily were randomized to BZA 20 mg/CE 0.45 mg, BZA 20 mg/CE 0.625 mg, or placebo. In these secondary efficacy analyses, the Medical Outcomes Study (MOS) sleep scale and Menopause-Specific Quality of Life (MENQOL) questionnaires and the Menopause Symptoms Treatment Satisfaction Questionnaire (MS-TSQ) evaluated measures of sleep, menopausal symptoms, and satisfaction with treatment, respectively. Results A total of 318 subjects (mean age, 53.4 years) received ≥1 dose of study drug. At Week 12, BZA 20 mg/CE 0.45 and 0.625 mg showed significant improvements over placebo in the MOS sleep scale for time to fall asleep, sleep adequacy, sleep disturbance, and sleep problems indexes I and II (P < 0.001). A reduction in hot flush frequency was significantly associated with improvement in sleep parameters (P < 0.05) based on linear regression and responder analyses. Both BZA/CE doses showed significantly greater improvements over placebo in vasomotor function and total MENQOL score (P < 0.001). Results of the MS-TSQ showed that subjects treated with BZA/CE versus placebo reported significantly greater overall satisfaction with treatment (P < 0.05), as well as greater satisfaction with sleep quality, ability to control hot flushes during the day and night, effect on mood/emotions, and tolerability. Conclusion Symptomatic postmenopausal women treated with BZA/CE experienced significant improvements in sleep parameters and overall HR-QOL." @default.
• W2034243341 created "2016-06-24" @default.
• W2034243341 creator A5054248653 @default.
• W2034243341 creator A5059727205 @default.
• W2034243341 creator A5061760107 @default.
• W2034243341 creator A5071092589 @default.
• W2034243341 creator A5087111403 @default.
• W2034243341 creator A5087125238 @default.
• W2034243341 date "2009-08-01" @default.
• W2034243341 modified "2023-09-27" @default.
• W2034243341 title "Bazedoxifene/conjugated estrogens and quality of life in postmenopausal women" @default.
• W2034243341 cites W1969313589 @default.
• W2034243341 cites W1972111416 @default.
• W2034243341 cites W1973170233 @default.
• W2034243341 cites W1976389084 @default.
• W2034243341 cites W1979228521 @default.
• W2034243341 cites W1985785776 @default.
• W2034243341 cites W1985992498 @default.
• W2034243341 cites W1991681674 @default.
• W2034243341 cites W2009249344 @default.
• W2034243341 cites W2013093446 @default.
• W2034243341 cites W2016677964 @default.
• W2034243341 cites W2019979380 @default.
• W2034243341 cites W2021804760 @default.
• W2034243341 cites W2026537685 @default.
• W2034243341 cites W2030663930 @default.
• W2034243341 cites W2035593552 @default.
• W2034243341 cites W2038976913 @default.
• W2034243341 cites W2039751703 @default.
• W2034243341 cites W2047166790 @default.
• W2034243341 cites W2047172236 @default.
• W2034243341 cites W2055098380 @default.
• W2034243341 cites W2059897929 @default.
• W2034243341 cites W2060775470 @default.
• W2034243341 cites W2064069306 @default.
• W2034243341 cites W2066591855 @default.
• W2034243341 cites W2069732107 @default.
• W2034243341 cites W2069883047 @default.
• W2034243341 cites W2070284062 @default.
• W2034243341 cites W2077638573 @default.
• W2034243341 cites W2091308831 @default.
• W2034243341 cites W2092025335 @default.
• W2034243341 cites W2093999587 @default.
• W2034243341 cites W2100260971 @default.
• W2034243341 cites W2108506257 @default.
• W2034243341 cites W2134262258 @default.
• W2034243341 cites W2143515930 @default.
• W2034243341 cites W2149154958 @default.
• W2034243341 cites W2150127964 @default.
• W2034243341 cites W2151780302 @default.
• W2034243341 cites W2159416358 @default.
• W2034243341 cites W4234259533 @default.
• W2034243341 cites W4236705518 @default.
• W2034243341 cites W4255045039 @default.
• W2034243341 cites W4376631872 @default.
• W2034243341 doi "https://doi.org/10.1016/j.maturitas.2009.06.006" @default.
• W2034243341 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19647382" @default.
• W2034243341 hasPublicationYear "2009" @default.
• W2034243341 type Work @default.
• W2034243341 sameAs 2034243341 @default.
• W2034243341 citedByCount "86" @default.
• W2034243341 countsByYear W20342433412012 @default.
• W2034243341 countsByYear W20342433412013 @default.
• W2034243341 countsByYear W20342433412014 @default.
• W2034243341 countsByYear W20342433412015 @default.
• W2034243341 countsByYear W20342433412016 @default.
• W2034243341 countsByYear W20342433412017 @default.
• W2034243341 countsByYear W20342433412018 @default.
• W2034243341 countsByYear W20342433412019 @default.
• W2034243341 countsByYear W20342433412020 @default.
• W2034243341 countsByYear W20342433412021 @default.
• W2034243341 countsByYear W20342433412022 @default.
• W2034243341 countsByYear W20342433412023 @default.
• W2034243341 crossrefType "journal-article" @default.
• W2034243341 hasAuthorship W2034243341A5054248653 @default.
• W2034243341 hasAuthorship W2034243341A5059727205 @default.
• W2034243341 hasAuthorship W2034243341A5061760107 @default.
• W2034243341 hasAuthorship W2034243341A5071092589 @default.
• W2034243341 hasAuthorship W2034243341A5087111403 @default.
• W2034243341 hasAuthorship W2034243341A5087125238 @default.
• W2034243341 hasConcept C126322002 @default.
• W2034243341 hasConcept C142724271 @default.
• W2034243341 hasConcept C159110408 @default.
• W2034243341 hasConcept C1862650 @default.
• W2034243341 hasConcept C204787440 @default.
• W2034243341 hasConcept C27081682 @default.
• W2034243341 hasConcept C2776214587 @default.
• W2034243341 hasConcept C2778562196 @default.
• W2034243341 hasConcept C2779951463 @default.
• W2034243341 hasConcept C29456083 @default.
• W2034243341 hasConcept C71924100 @default.
• W2034243341 hasConceptScore W2034243341C126322002 @default.
• W2034243341 hasConceptScore W2034243341C142724271 @default.
• W2034243341 hasConceptScore W2034243341C159110408 @default.
• W2034243341 hasConceptScore W2034243341C1862650 @default.
• W2034243341 hasConceptScore W2034243341C204787440 @default.
• W2034243341 hasConceptScore W2034243341C27081682 @default.
• W2034243341 hasConceptScore W2034243341C2776214587 @default.

• next