FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034245104> ?p ?o ?g. }

• W2034245104 endingPage "202" @default.
• W2034245104 startingPage "196" @default.
• W2034245104 abstract "T cells express two different types of voltage-independent Ca(2+)-activated K(+) channels with small (SK) and intermediate (IK) conductance that serve important roles in the activation of T lymphocytes. In contrast to the IK channels from T lymphocytes which are upregulated upon mitogen stimulation, SK channels of Jurkat T cells, a human leukemic T cell line, are constitutively expressed even in the absence of mitogenic stimulation. We have used patch-clamp recordings from transfected or injected mammalian cells to show that the cloned SK2 channel demonstrates the biophysical and pharmacological properties of the majority of K(Ca) channels in Jurkat T cells. The cloned and native channels are voltage-independent, Ca(2+)-activated, apamin-sensitive, show an equivalent voltage-dependent Ba(2+) block and possess a similar ion selectivity. In addition, we used the polymerase chain reaction to demonstrate the presence of SK2 mRNA in Jurkat T cells, whereas SK3 transcripts encoding the other cloned apamin-sensitive SK channel were not detected. These data suggest that the voltage-independent apamin-sensitive K(Ca) channel in Jurkat T cells represents the recently cloned SK2 channel." @default.
• W2034245104 created "2016-06-24" @default.
• W2034245104 creator A5027032779 @default.
• W2034245104 creator A5067506966 @default.
• W2034245104 creator A5078431075 @default.
• W2034245104 date "2000-03-08" @default.
• W2034245104 modified "2023-10-17" @default.
• W2034245104 title "SK2 encodes the apamin‐sensitive Ca²⁺‐activated K⁺ channels in the human leukemic T cell line, Jurkat" @default.
• W2034245104 cites W1868380476 @default.
• W2034245104 cites W1985958365 @default.
• W2034245104 cites W1990571474 @default.
• W2034245104 cites W2009667219 @default.
• W2034245104 cites W2012462160 @default.
• W2034245104 cites W2012570457 @default.
• W2034245104 cites W2012861937 @default.
• W2034245104 cites W2020477012 @default.
• W2034245104 cites W2042670053 @default.
• W2034245104 cites W2042834368 @default.
• W2034245104 cites W2048829459 @default.
• W2034245104 cites W2051040059 @default.
• W2034245104 cites W2053546226 @default.
• W2034245104 cites W2065558767 @default.
• W2034245104 cites W2091344256 @default.
• W2034245104 cites W2108442939 @default.
• W2034245104 cites W2139312497 @default.
• W2034245104 cites W2141578443 @default.
• W2034245104 cites W2165444973 @default.
• W2034245104 cites W2165918134 @default.
• W2034245104 cites W2185280366 @default.
• W2034245104 doi "https://doi.org/10.1016/s0014-5793(00)01236-9" @default.
• W2034245104 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10713270" @default.
• W2034245104 hasPublicationYear "2000" @default.
• W2034245104 type Work @default.
• W2034245104 sameAs 2034245104 @default.
• W2034245104 citedByCount "42" @default.
• W2034245104 countsByYear W20342451042013 @default.
• W2034245104 countsByYear W20342451042014 @default.
• W2034245104 countsByYear W20342451042018 @default.
• W2034245104 countsByYear W20342451042020 @default.
• W2034245104 countsByYear W20342451042021 @default.
• W2034245104 countsByYear W20342451042023 @default.
• W2034245104 crossrefType "journal-article" @default.
• W2034245104 hasAuthorship W2034245104A5027032779 @default.
• W2034245104 hasAuthorship W2034245104A5067506966 @default.
• W2034245104 hasAuthorship W2034245104A5078431075 @default.
• W2034245104 hasConcept C12554922 @default.
• W2034245104 hasConcept C134018914 @default.
• W2034245104 hasConcept C147944092 @default.
• W2034245104 hasConcept C149786707 @default.
• W2034245104 hasConcept C153911025 @default.
• W2034245104 hasConcept C169760540 @default.
• W2034245104 hasConcept C170493617 @default.
• W2034245104 hasConcept C179464577 @default.
• W2034245104 hasConcept C185263204 @default.
• W2034245104 hasConcept C24998067 @default.
• W2034245104 hasConcept C2776090121 @default.
• W2034245104 hasConcept C2776919887 @default.
• W2034245104 hasConcept C2780419564 @default.
• W2034245104 hasConcept C50254741 @default.
• W2034245104 hasConcept C54009773 @default.
• W2034245104 hasConcept C54355233 @default.
• W2034245104 hasConcept C55493867 @default.
• W2034245104 hasConcept C81885089 @default.
• W2034245104 hasConcept C83743174 @default.
• W2034245104 hasConcept C86803240 @default.
• W2034245104 hasConcept C8891405 @default.
• W2034245104 hasConcept C95444343 @default.
• W2034245104 hasConceptScore W2034245104C12554922 @default.
• W2034245104 hasConceptScore W2034245104C134018914 @default.
• W2034245104 hasConceptScore W2034245104C147944092 @default.
• W2034245104 hasConceptScore W2034245104C149786707 @default.
• W2034245104 hasConceptScore W2034245104C153911025 @default.
• W2034245104 hasConceptScore W2034245104C169760540 @default.
• W2034245104 hasConceptScore W2034245104C170493617 @default.
• W2034245104 hasConceptScore W2034245104C179464577 @default.
• W2034245104 hasConceptScore W2034245104C185263204 @default.
• W2034245104 hasConceptScore W2034245104C24998067 @default.
• W2034245104 hasConceptScore W2034245104C2776090121 @default.
• W2034245104 hasConceptScore W2034245104C2776919887 @default.
• W2034245104 hasConceptScore W2034245104C2780419564 @default.
• W2034245104 hasConceptScore W2034245104C50254741 @default.
• W2034245104 hasConceptScore W2034245104C54009773 @default.
• W2034245104 hasConceptScore W2034245104C54355233 @default.
• W2034245104 hasConceptScore W2034245104C55493867 @default.
• W2034245104 hasConceptScore W2034245104C81885089 @default.
• W2034245104 hasConceptScore W2034245104C83743174 @default.
• W2034245104 hasConceptScore W2034245104C86803240 @default.
• W2034245104 hasConceptScore W2034245104C8891405 @default.
• W2034245104 hasConceptScore W2034245104C95444343 @default.
• W2034245104 hasIssue "2-3" @default.
• W2034245104 hasLocation W20342451041 @default.
• W2034245104 hasLocation W20342451042 @default.
• W2034245104 hasOpenAccess W2034245104 @default.
• W2034245104 hasPrimaryLocation W20342451041 @default.
• W2034245104 hasRelatedWork W1570333985 @default.
• W2034245104 hasRelatedWork W1968135647 @default.
• W2034245104 hasRelatedWork W2005317840 @default.
• W2034245104 hasRelatedWork W2012558502 @default.

• next