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• W2034246680 abstract "To investigate the molecular mechanism of the melatonin rhythm in the mammalian retina, we examined the temporal mRNA expression pattern of serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AA-NAT; the rate-limiting enzyme in melatonin synthesis) in the rat retina. Northern blot analysis showed that in a daily light-dark cycle retinal AA-NAT mRNA was low during the day and increased more than threefold at night, and this daily rhythm persisted even in constant darkness. These findings suggest that AA-NAT mRNA expression in the rat retina is regulated by an endogenous circadian clock." @default.
• W2034246680 created "2016-06-24" @default.
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• W2034246680 date "1998-04-01" @default.
• W2034246680 modified "2023-09-25" @default.
• W2034246680 title "Circadian expression of serotonin N-acetyltransferase mRNA in the rat retina" @default.
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• W2034246680 doi "https://doi.org/10.1016/s0304-3940(98)00189-x" @default.
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