FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034251015> ?p ?o ?g. }

• W2034251015 endingPage "8372" @default.
• W2034251015 startingPage "8368" @default.
• W2034251015 abstract "We have examined the acute effects of insulin and isoproterenol on the phosphorylation state of the insulin-regulatable glucose transporter (IRGT) in rat adipocytes. The IRGT was immunoprecipitated from either detergent-solubilized whole-cell homogenates or subcellular fractions of 32P-labeled fat cells and subjected to sodium dodecyl sulfate/polyacrylamide gel electrophoresis. The 32P-labeled IRGT was detected by autoradiography as a species of apparent Mr 46,000. Insulin stimulated translocation of the IRGT from low-density microsomes to the plasma membrane but did not affect phosphorylation of the transporter in either fraction. Isoproterenol inhibited insulin-stimulated glucose transport by 40% but was without effect on the subcellular distribution of the transporter in either the presence or absence of insulin. Isoproterenol stimulated phosphorylation of the IRGT 2-fold. Incubating cells with dibutyryl-cAMP and 8-bromo-cAMP also stimulated phosphorylation 2-fold, and the transporter was phosphorylated in vitro when IRGT-enriched vesicles were incubated with cAMP-dependent protein kinase and [gamma-32P]ATP. These results suggest that isoproterenol stimulates phosphorylation of the IRGT via a cAMP-dependent pathway and that phosphorylation of the transporter may modulate its ability to transport glucose." @default.
• W2034251015 created "2016-06-24" @default.
• W2034251015 creator A5002073180 @default.
• W2034251015 creator A5014643889 @default.
• W2034251015 creator A5058541998 @default.
• W2034251015 date "1989-11-01" @default.
• W2034251015 modified "2023-10-18" @default.
• W2034251015 title "Isoproterenol stimulates phosphorylation of the insulin-regulatable glucose transporter in rat adipocytes." @default.
• W2034251015 cites W102091409 @default.
• W2034251015 cites W1483819615 @default.
• W2034251015 cites W1541408984 @default.
• W2034251015 cites W1554235282 @default.
• W2034251015 cites W1554751699 @default.
• W2034251015 cites W1576590564 @default.
• W2034251015 cites W1584581247 @default.
• W2034251015 cites W1636454465 @default.
• W2034251015 cites W1675030349 @default.
• W2034251015 cites W1886888420 @default.
• W2034251015 cites W1970081885 @default.
• W2034251015 cites W1976177239 @default.
• W2034251015 cites W1984950565 @default.
• W2034251015 cites W1991485226 @default.
• W2034251015 cites W2000977514 @default.
• W2034251015 cites W2001736800 @default.
• W2034251015 cites W2010820226 @default.
• W2034251015 cites W2018289835 @default.
• W2034251015 cites W2021366242 @default.
• W2034251015 cites W2028642327 @default.
• W2034251015 cites W2030345672 @default.
• W2034251015 cites W2037504389 @default.
• W2034251015 cites W2047967376 @default.
• W2034251015 cites W2070892520 @default.
• W2034251015 cites W2074783201 @default.
• W2034251015 cites W2096996169 @default.
• W2034251015 cites W2100837269 @default.
• W2034251015 cites W2136433521 @default.
• W2034251015 cites W2143873575 @default.
• W2034251015 cites W2409371070 @default.
• W2034251015 cites W2410339333 @default.
• W2034251015 cites W2416393035 @default.
• W2034251015 cites W4232534952 @default.
• W2034251015 doi "https://doi.org/10.1073/pnas.86.21.8368" @default.
• W2034251015 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/298282" @default.
• W2034251015 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2554313" @default.
• W2034251015 hasPublicationYear "1989" @default.
• W2034251015 type Work @default.
• W2034251015 sameAs 2034251015 @default.
• W2034251015 citedByCount "72" @default.
• W2034251015 countsByYear W20342510152013 @default.
• W2034251015 countsByYear W20342510152014 @default.
• W2034251015 countsByYear W20342510152015 @default.
• W2034251015 countsByYear W20342510152016 @default.
• W2034251015 countsByYear W20342510152017 @default.
• W2034251015 crossrefType "journal-article" @default.
• W2034251015 hasAuthorship W2034251015A5002073180 @default.
• W2034251015 hasAuthorship W2034251015A5014643889 @default.
• W2034251015 hasAuthorship W2034251015A5058541998 @default.
• W2034251015 hasBestOaLocation W20342510151 @default.
• W2034251015 hasConcept C104317684 @default.
• W2034251015 hasConcept C11960822 @default.
• W2034251015 hasConcept C126322002 @default.
• W2034251015 hasConcept C134018914 @default.
• W2034251015 hasConcept C149011108 @default.
• W2034251015 hasConcept C161573976 @default.
• W2034251015 hasConcept C185592680 @default.
• W2034251015 hasConcept C2779306644 @default.
• W2034251015 hasConcept C55493867 @default.
• W2034251015 hasConcept C71924100 @default.
• W2034251015 hasConcept C86803240 @default.
• W2034251015 hasConcept C89200155 @default.
• W2034251015 hasConcept C97029542 @default.
• W2034251015 hasConceptScore W2034251015C104317684 @default.
• W2034251015 hasConceptScore W2034251015C11960822 @default.
• W2034251015 hasConceptScore W2034251015C126322002 @default.
• W2034251015 hasConceptScore W2034251015C134018914 @default.
• W2034251015 hasConceptScore W2034251015C149011108 @default.
• W2034251015 hasConceptScore W2034251015C161573976 @default.
• W2034251015 hasConceptScore W2034251015C185592680 @default.
• W2034251015 hasConceptScore W2034251015C2779306644 @default.
• W2034251015 hasConceptScore W2034251015C55493867 @default.
• W2034251015 hasConceptScore W2034251015C71924100 @default.
• W2034251015 hasConceptScore W2034251015C86803240 @default.
• W2034251015 hasConceptScore W2034251015C89200155 @default.
• W2034251015 hasConceptScore W2034251015C97029542 @default.
• W2034251015 hasIssue "21" @default.
• W2034251015 hasLocation W20342510151 @default.
• W2034251015 hasLocation W20342510152 @default.
• W2034251015 hasLocation W20342510153 @default.
• W2034251015 hasLocation W20342510154 @default.
• W2034251015 hasOpenAccess W2034251015 @default.
• W2034251015 hasPrimaryLocation W20342510151 @default.
• W2034251015 hasRelatedWork W1971859682 @default.
• W2034251015 hasRelatedWork W1976259407 @default.
• W2034251015 hasRelatedWork W2018364757 @default.
• W2034251015 hasRelatedWork W2061240375 @default.
• W2034251015 hasRelatedWork W2080338048 @default.
• W2034251015 hasRelatedWork W2096323324 @default.
• W2034251015 hasRelatedWork W2121387145 @default.

• next