Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034253411> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2034253411 endingPage "632" @default.
- W2034253411 startingPage "629" @default.
- W2034253411 abstract "N-(Substituted-phenyl)-D-xylopyranosylamines and their O-peracetyl derivatives have been synthesized and tested for their ability (a) to inhibit the replication of cultured B16 melanoma cells and (b) to modify the synthesis of glycosaminoglycans by these neoplastic cells. The most cytotoxic compound synthesized was N-(p-methoxyphenyl)-D-xylopyranosylamine (6), which produced 50% inhibition of cellular proliferation at a concentration of 2 microM; a number of other compounds were relatively cytotoxic, causing 50% inhibition of cell replication at levels of 12 to 25 microM. Several of the synthesized xylosides appeared to be capable of serving as artificial initiators of glycosaminoglycan synthesis, with the most active agents causing approximately 2- to 4-fold increases in the incorporation of [35S]sulfate into the glycosaminoglycans of B16 melanoma cells excreted into the culture medium." @default.
- W2034253411 created "2016-06-24" @default.
- W2034253411 creator A5043512123 @default.
- W2034253411 creator A5053275663 @default.
- W2034253411 creator A5075620272 @default.
- W2034253411 creator A5078454492 @default.
- W2034253411 date "1983-05-01" @default.
- W2034253411 modified "2023-09-25" @default.
- W2034253411 title "Synthesis of N-(substituted phenyl)-D-xylopyranosylamines as potential modifiers of the formation of glycosaminoglycans" @default.
- W2034253411 doi "https://doi.org/10.1021/jm00359a002" @default.
- W2034253411 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6842504" @default.
- W2034253411 hasPublicationYear "1983" @default.
- W2034253411 type Work @default.
- W2034253411 sameAs 2034253411 @default.
- W2034253411 citedByCount "7" @default.
- W2034253411 countsByYear W20342534112020 @default.
- W2034253411 countsByYear W20342534112021 @default.
- W2034253411 crossrefType "journal-article" @default.
- W2034253411 hasAuthorship W2034253411A5043512123 @default.
- W2034253411 hasAuthorship W2034253411A5053275663 @default.
- W2034253411 hasAuthorship W2034253411A5075620272 @default.
- W2034253411 hasAuthorship W2034253411A5078454492 @default.
- W2034253411 hasConcept C109316439 @default.
- W2034253411 hasConcept C114373084 @default.
- W2034253411 hasConcept C153074725 @default.
- W2034253411 hasConcept C154317977 @default.
- W2034253411 hasConcept C185592680 @default.
- W2034253411 hasConcept C202751555 @default.
- W2034253411 hasConcept C54355233 @default.
- W2034253411 hasConcept C55493867 @default.
- W2034253411 hasConcept C62112901 @default.
- W2034253411 hasConcept C71240020 @default.
- W2034253411 hasConcept C81885089 @default.
- W2034253411 hasConcept C86803240 @default.
- W2034253411 hasConceptScore W2034253411C109316439 @default.
- W2034253411 hasConceptScore W2034253411C114373084 @default.
- W2034253411 hasConceptScore W2034253411C153074725 @default.
- W2034253411 hasConceptScore W2034253411C154317977 @default.
- W2034253411 hasConceptScore W2034253411C185592680 @default.
- W2034253411 hasConceptScore W2034253411C202751555 @default.
- W2034253411 hasConceptScore W2034253411C54355233 @default.
- W2034253411 hasConceptScore W2034253411C55493867 @default.
- W2034253411 hasConceptScore W2034253411C62112901 @default.
- W2034253411 hasConceptScore W2034253411C71240020 @default.
- W2034253411 hasConceptScore W2034253411C81885089 @default.
- W2034253411 hasConceptScore W2034253411C86803240 @default.
- W2034253411 hasIssue "5" @default.
- W2034253411 hasLocation W20342534111 @default.
- W2034253411 hasLocation W20342534112 @default.
- W2034253411 hasOpenAccess W2034253411 @default.
- W2034253411 hasPrimaryLocation W20342534111 @default.
- W2034253411 hasRelatedWork W1965148186 @default.
- W2034253411 hasRelatedWork W1966690465 @default.
- W2034253411 hasRelatedWork W1972341029 @default.
- W2034253411 hasRelatedWork W1973999426 @default.
- W2034253411 hasRelatedWork W1983661946 @default.
- W2034253411 hasRelatedWork W2033486343 @default.
- W2034253411 hasRelatedWork W2046658802 @default.
- W2034253411 hasRelatedWork W2067983295 @default.
- W2034253411 hasRelatedWork W2093313172 @default.
- W2034253411 hasRelatedWork W2174243521 @default.
- W2034253411 hasVolume "26" @default.
- W2034253411 isParatext "false" @default.
- W2034253411 isRetracted "false" @default.
- W2034253411 magId "2034253411" @default.
- W2034253411 workType "article" @default.