Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034259170> ?p ?o ?g. }
- W2034259170 endingPage "1165" @default.
- W2034259170 startingPage "1160" @default.
- W2034259170 abstract "Myocardial contractile reserve has been shown to provide important prognostic information in patients with heart failure. We hypothesized that myocardial contractile reserve would predict left ventricular (LV) reverse remodeling after cardiac resynchronization therapy (CRT). Thirty-one consecutive patients with heart failure (LV ejection fraction [LVEF] 26% ± 7%, 35% nonischemic cardiomyopathy) underwent echocardiography during low-dose dobutamine infusion before CRT implantation to assess global contractile reserve (improvement in LVEF) and local contractile reserve in the region of the LV pacing lead (assessed by radial strain using speckle tracking analysis). Responders were defined by a decrease in LV end-systolic volume ≥15% after 6 months of CRT. During low-dose dobutamine infusion, responders showed a greater increase in LVEF compared with nonresponders (Δ 13% ± 8% vs 3% ± 4%, P < .001). Furthermore, contractile reserve was directly related to improvement in LVEF after 6 months of CRT (r = 0.80, P < .001). Moreover, a cutoff value of >7.5% increase in dobutamine-induced LVEF exhibited a sensitivity of 76% and a specificity of 86% to predict response after 6 months of CRT (area under the curve 0.87). Lastly, contractile reserve in the region in the LV pacing lead was present only in responders (Δ strain during low-dose dobutamine 6% ± 5% in responders vs −1% ± 4% in nonresponders, P = .002). The current study demonstrates that myocardial contractile reserve (>7.5% increase in LVEF during low-dose dobutamine infusion) predicts LV reverse remodeling after CRT." @default.
- W2034259170 created "2016-06-24" @default.
- W2034259170 creator A5006862347 @default.
- W2034259170 creator A5053011724 @default.
- W2034259170 creator A5067088569 @default.
- W2034259170 creator A5067431731 @default.
- W2034259170 creator A5079671183 @default.
- W2034259170 creator A5087758271 @default.
- W2034259170 creator A5091902817 @default.
- W2034259170 date "2007-12-01" @default.
- W2034259170 modified "2023-10-17" @default.
- W2034259170 title "Myocardial contractile reserve predicts improvement in left ventricular function after cardiac resynchronization therapy" @default.
- W2034259170 cites W1966957613 @default.
- W2034259170 cites W1971646179 @default.
- W2034259170 cites W1982737397 @default.
- W2034259170 cites W1986817239 @default.
- W2034259170 cites W1997183811 @default.
- W2034259170 cites W2007385541 @default.
- W2034259170 cites W2011938263 @default.
- W2034259170 cites W2012047353 @default.
- W2034259170 cites W2022493479 @default.
- W2034259170 cites W2041999850 @default.
- W2034259170 cites W2045526719 @default.
- W2034259170 cites W2046712202 @default.
- W2034259170 cites W2050412362 @default.
- W2034259170 cites W2054181865 @default.
- W2034259170 cites W2073523821 @default.
- W2034259170 cites W2079861388 @default.
- W2034259170 cites W2109584088 @default.
- W2034259170 cites W2116375266 @default.
- W2034259170 cites W2124282085 @default.
- W2034259170 cites W2127251235 @default.
- W2034259170 cites W2130907431 @default.
- W2034259170 cites W2170281616 @default.
- W2034259170 cites W2567948445 @default.
- W2034259170 cites W2990123797 @default.
- W2034259170 cites W3014124860 @default.
- W2034259170 cites W3144470180 @default.
- W2034259170 cites W4361868645 @default.
- W2034259170 doi "https://doi.org/10.1016/j.ahj.2007.07.035" @default.
- W2034259170 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18035090" @default.
- W2034259170 hasPublicationYear "2007" @default.
- W2034259170 type Work @default.
- W2034259170 sameAs 2034259170 @default.
- W2034259170 citedByCount "84" @default.
- W2034259170 countsByYear W20342591702012 @default.
- W2034259170 countsByYear W20342591702013 @default.
- W2034259170 countsByYear W20342591702014 @default.
- W2034259170 countsByYear W20342591702015 @default.
- W2034259170 countsByYear W20342591702016 @default.
- W2034259170 countsByYear W20342591702017 @default.
- W2034259170 countsByYear W20342591702018 @default.
- W2034259170 countsByYear W20342591702019 @default.
- W2034259170 countsByYear W20342591702021 @default.
- W2034259170 countsByYear W20342591702023 @default.
- W2034259170 crossrefType "journal-article" @default.
- W2034259170 hasAuthorship W2034259170A5006862347 @default.
- W2034259170 hasAuthorship W2034259170A5053011724 @default.
- W2034259170 hasAuthorship W2034259170A5067088569 @default.
- W2034259170 hasAuthorship W2034259170A5067431731 @default.
- W2034259170 hasAuthorship W2034259170A5079671183 @default.
- W2034259170 hasAuthorship W2034259170A5087758271 @default.
- W2034259170 hasAuthorship W2034259170A5091902817 @default.
- W2034259170 hasConcept C126322002 @default.
- W2034259170 hasConcept C164705383 @default.
- W2034259170 hasConcept C178853913 @default.
- W2034259170 hasConcept C2776034619 @default.
- W2034259170 hasConcept C2778198053 @default.
- W2034259170 hasConcept C2778797674 @default.
- W2034259170 hasConcept C2781185063 @default.
- W2034259170 hasConcept C71924100 @default.
- W2034259170 hasConcept C78085059 @default.
- W2034259170 hasConceptScore W2034259170C126322002 @default.
- W2034259170 hasConceptScore W2034259170C164705383 @default.
- W2034259170 hasConceptScore W2034259170C178853913 @default.
- W2034259170 hasConceptScore W2034259170C2776034619 @default.
- W2034259170 hasConceptScore W2034259170C2778198053 @default.
- W2034259170 hasConceptScore W2034259170C2778797674 @default.
- W2034259170 hasConceptScore W2034259170C2781185063 @default.
- W2034259170 hasConceptScore W2034259170C71924100 @default.
- W2034259170 hasConceptScore W2034259170C78085059 @default.
- W2034259170 hasIssue "6" @default.
- W2034259170 hasLocation W20342591701 @default.
- W2034259170 hasLocation W20342591702 @default.
- W2034259170 hasOpenAccess W2034259170 @default.
- W2034259170 hasPrimaryLocation W20342591701 @default.
- W2034259170 hasRelatedWork W1971710084 @default.
- W2034259170 hasRelatedWork W2028196543 @default.
- W2034259170 hasRelatedWork W2072108749 @default.
- W2034259170 hasRelatedWork W2438917488 @default.
- W2034259170 hasRelatedWork W2481234813 @default.
- W2034259170 hasRelatedWork W2891746874 @default.
- W2034259170 hasRelatedWork W2920829402 @default.
- W2034259170 hasRelatedWork W3164268473 @default.
- W2034259170 hasRelatedWork W322030742 @default.
- W2034259170 hasRelatedWork W4207030337 @default.
- W2034259170 hasVolume "154" @default.
- W2034259170 isParatext "false" @default.