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- W2034261650 endingPage "502" @default.
- W2034261650 startingPage "490" @default.
- W2034261650 abstract "The biological attack conducted through the US postal system in 2001 broadened the threat posed by anthrax from one pertinent mainly to soldiers on the battlefield to one understood to exist throughout our society. The expansion of the threatened population placed greater emphasis on the reexamination of how we vaccinate against Bacillus anthracis. The currently-licensed Anthrax Vaccine, Adsorbed (AVA) and Anthrax Vaccine, Precipitated (AVP) are capable of generating a protective immune response but are hampered by shortcomings that make their widespread use undesirable or infeasible. Efforts to gain US Food and Drug Administration (FDA) approval for licensure of a second generation recombinant protective antigen (rPA)-based anthrax vaccine are ongoing. However, this vaccine’s reliance on the generation of a humoral immune response against a single virulence factor has led a number of scientists to conclude that the vaccine is likely not the final solution to optimal anthrax vaccine design. Other vaccine approaches, which seek a more comprehensive immune response targeted at multiple components of the B. anthracis organism, are under active investigation. This review seeks to summarize work that has been done to build on the current PA-based vaccine methodology and to evaluate the search for future anthrax prophylaxis strategies." @default.
- W2034261650 created "2016-06-24" @default.
- W2034261650 creator A5047900679 @default.
- W2034261650 creator A5072024836 @default.
- W2034261650 creator A5083929007 @default.
- W2034261650 date "2009-12-01" @default.
- W2034261650 modified "2023-10-16" @default.
- W2034261650 title "Anthrax vaccination strategies" @default.
- W2034261650 cites W114851923 @default.
- W2034261650 cites W1497287745 @default.
- W2034261650 cites W15449065 @default.
- W2034261650 cites W1592698292 @default.
- W2034261650 cites W183575158 @default.
- W2034261650 cites W1861465928 @default.
- W2034261650 cites W1866848852 @default.
- W2034261650 cites W1906629914 @default.
- W2034261650 cites W1964942318 @default.
- W2034261650 cites W1965688103 @default.
- W2034261650 cites W1966081484 @default.
- W2034261650 cites W1966241976 @default.
- W2034261650 cites W1966924859 @default.
- W2034261650 cites W1967505271 @default.
- W2034261650 cites W1967825129 @default.
- W2034261650 cites W1968939990 @default.
- W2034261650 cites W1969366735 @default.
- W2034261650 cites W1972146674 @default.
- W2034261650 cites W197782945 @default.
- W2034261650 cites W1979958088 @default.
- W2034261650 cites W1982228457 @default.
- W2034261650 cites W1984137993 @default.
- W2034261650 cites W1984740331 @default.
- W2034261650 cites W1987827316 @default.
- W2034261650 cites W1988574690 @default.
- W2034261650 cites W1988827698 @default.
- W2034261650 cites W1990457946 @default.
- W2034261650 cites W1994513272 @default.
- W2034261650 cites W1996413486 @default.
- W2034261650 cites W1997560169 @default.
- W2034261650 cites W1999619898 @default.
- W2034261650 cites W1999871797 @default.
- W2034261650 cites W2000171430 @default.
- W2034261650 cites W2004292086 @default.
- W2034261650 cites W2007185863 @default.
- W2034261650 cites W2008643849 @default.
- W2034261650 cites W2010124203 @default.
- W2034261650 cites W2011808375 @default.
- W2034261650 cites W2013506832 @default.
- W2034261650 cites W2013947028 @default.
- W2034261650 cites W2014336328 @default.
- W2034261650 cites W2019134686 @default.
- W2034261650 cites W2019887962 @default.
- W2034261650 cites W2022177606 @default.
- W2034261650 cites W2022585674 @default.
- W2034261650 cites W2022712848 @default.
- W2034261650 cites W2024244991 @default.
- W2034261650 cites W2024266520 @default.
- W2034261650 cites W2024981220 @default.
- W2034261650 cites W2028988508 @default.
- W2034261650 cites W2029821093 @default.
- W2034261650 cites W2031155528 @default.
- W2034261650 cites W2031175296 @default.
- W2034261650 cites W2032310151 @default.
- W2034261650 cites W2032389578 @default.
- W2034261650 cites W2033062075 @default.
- W2034261650 cites W2035696611 @default.
- W2034261650 cites W2035922118 @default.
- W2034261650 cites W2038805615 @default.
- W2034261650 cites W2040623131 @default.
- W2034261650 cites W2041392157 @default.
- W2034261650 cites W2041882429 @default.
- W2034261650 cites W2047785999 @default.
- W2034261650 cites W2048179144 @default.
- W2034261650 cites W2050150132 @default.
- W2034261650 cites W2055854798 @default.
- W2034261650 cites W2056800820 @default.
- W2034261650 cites W2058812528 @default.
- W2034261650 cites W2058942629 @default.
- W2034261650 cites W2060463358 @default.
- W2034261650 cites W2060953130 @default.
- W2034261650 cites W2061952369 @default.
- W2034261650 cites W2063949704 @default.
- W2034261650 cites W2064456376 @default.
- W2034261650 cites W2064505443 @default.
- W2034261650 cites W2066524113 @default.
- W2034261650 cites W2067748709 @default.
- W2034261650 cites W2068173199 @default.
- W2034261650 cites W2068806092 @default.
- W2034261650 cites W2069245581 @default.
- W2034261650 cites W2069721374 @default.
- W2034261650 cites W2075867982 @default.
- W2034261650 cites W2076654212 @default.
- W2034261650 cites W2080141237 @default.
- W2034261650 cites W2082143240 @default.
- W2034261650 cites W2083546878 @default.
- W2034261650 cites W2083603978 @default.
- W2034261650 cites W2089967327 @default.
- W2034261650 cites W2091839211 @default.
- W2034261650 cites W2092516500 @default.