FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034262331> ?p ?o ?g. }

• W2034262331 endingPage "1319" @default.
• W2034262331 startingPage "1313" @default.
• W2034262331 abstract "An increase in the incidence of oral cancer among patients younger than 40 years has been reported worldwide. It has been suggested that the disease behaves more aggressively among young people.To evaluate the clinical and biologic behavior of tongue cancer among younger patients.Data on all patients younger than 40 years in whom tongue cancer was diagnosed in Finland between 1980 and 1989 (34 cases) were collected; pertinent clinical data were available for risk factor screening. A follow-up of at least 5 years or until death was available for all 34 patients. Immunocytochemical staining techniques were used to assess the expression of p53 and bcl-2 proteins, and p53 mutation analysis was performed by using the nonradioactive single-strand conformation polymorphism technique.The incidence of tongue cancer in this age group in Finland did not change during the study period. The clinical behavior of tongue cancer in young people was not more aggressive compared with that of older patients in general, with the overall 5-year survival being as good as 70.6%. Altogether, p53 mutations were found in 17 of 33 tumors (51.5%). The p53 and bcl-2 protein expression was strong or moderate in 33.3% and 30.3% of the samples, respectively. Intense p53 protein expression was associated with the larger tumor size (P < .05). The poorest prognosis was found in patients with tumors greater than 4 cm in diameter (P = .01) or moderately or poorly differentiated cancer (P = .01). There was a trend for the adverse prognosis to accumulate in patients with moderately or poorly differentiated carcinoma and mutations in p53 (P = .09).The cause of tongue cancer in patients younger than 40 years seems to be multifactorial. Those patients had a similar clinical course, prognosis, and function of p53 as found in the reports of a normal age variation. Mutations of p53 seemed to be an additional prognostic marker that was associated with moderate or poor differentiation of the tumors." @default.
• W2034262331 created "2016-06-24" @default.
• W2034262331 creator A5021730709 @default.
• W2034262331 creator A5030107910 @default.
• W2034262331 creator A5042858205 @default.
• W2034262331 creator A5064193017 @default.
• W2034262331 date "1996-12-01" @default.
• W2034262331 modified "2023-10-14" @default.
• W2034262331 title "Cancer of the Tongue in Patients Younger Than 40 Years: A Distinct Entity?" @default.
• W2034262331 cites W140845169 @default.
• W2034262331 cites W1501970115 @default.
• W2034262331 cites W1763110138 @default.
• W2034262331 cites W1977937099 @default.
• W2034262331 cites W1980535334 @default.
• W2034262331 cites W1994064246 @default.
• W2034262331 cites W1999313421 @default.
• W2034262331 cites W2009348383 @default.
• W2034262331 cites W2012851660 @default.
• W2034262331 cites W2014343199 @default.
• W2034262331 cites W2032317977 @default.
• W2034262331 cites W2034919537 @default.
• W2034262331 cites W2035050504 @default.
• W2034262331 cites W2038621610 @default.
• W2034262331 cites W2057257609 @default.
• W2034262331 cites W2060906186 @default.
• W2034262331 cites W2071335464 @default.
• W2034262331 cites W2103087612 @default.
• W2034262331 cites W2159329636 @default.
• W2034262331 cites W2168977603 @default.
• W2034262331 cites W2182580930 @default.
• W2034262331 cites W2223163871 @default.
• W2034262331 cites W2262255644 @default.
• W2034262331 cites W2312732552 @default.
• W2034262331 cites W2412946266 @default.
• W2034262331 doi "https://doi.org/10.1001/archotol.1996.01890240021006" @default.
• W2034262331 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8956742" @default.
• W2034262331 hasPublicationYear "1996" @default.
• W2034262331 type Work @default.
• W2034262331 sameAs 2034262331 @default.
• W2034262331 citedByCount "106" @default.
• W2034262331 countsByYear W20342623312012 @default.
• W2034262331 countsByYear W20342623312013 @default.
• W2034262331 countsByYear W20342623312014 @default.
• W2034262331 countsByYear W20342623312015 @default.
• W2034262331 countsByYear W20342623312016 @default.
• W2034262331 countsByYear W20342623312017 @default.
• W2034262331 countsByYear W20342623312018 @default.
• W2034262331 countsByYear W20342623312019 @default.
• W2034262331 countsByYear W20342623312020 @default.
• W2034262331 countsByYear W20342623312021 @default.
• W2034262331 countsByYear W20342623312022 @default.
• W2034262331 countsByYear W20342623312023 @default.
• W2034262331 crossrefType "journal-article" @default.
• W2034262331 hasAuthorship W2034262331A5021730709 @default.
• W2034262331 hasAuthorship W2034262331A5030107910 @default.
• W2034262331 hasAuthorship W2034262331A5042858205 @default.
• W2034262331 hasAuthorship W2034262331A5064193017 @default.
• W2034262331 hasConcept C120665830 @default.
• W2034262331 hasConcept C121332964 @default.
• W2034262331 hasConcept C121608353 @default.
• W2034262331 hasConcept C126322002 @default.
• W2034262331 hasConcept C142724271 @default.
• W2034262331 hasConcept C143998085 @default.
• W2034262331 hasConcept C204232928 @default.
• W2034262331 hasConcept C2779744641 @default.
• W2034262331 hasConcept C2909289247 @default.
• W2034262331 hasConcept C3020813896 @default.
• W2034262331 hasConcept C61511704 @default.
• W2034262331 hasConcept C71924100 @default.
• W2034262331 hasConcept C90924648 @default.
• W2034262331 hasConceptScore W2034262331C120665830 @default.
• W2034262331 hasConceptScore W2034262331C121332964 @default.
• W2034262331 hasConceptScore W2034262331C121608353 @default.
• W2034262331 hasConceptScore W2034262331C126322002 @default.
• W2034262331 hasConceptScore W2034262331C142724271 @default.
• W2034262331 hasConceptScore W2034262331C143998085 @default.
• W2034262331 hasConceptScore W2034262331C204232928 @default.
• W2034262331 hasConceptScore W2034262331C2779744641 @default.
• W2034262331 hasConceptScore W2034262331C2909289247 @default.
• W2034262331 hasConceptScore W2034262331C3020813896 @default.
• W2034262331 hasConceptScore W2034262331C61511704 @default.
• W2034262331 hasConceptScore W2034262331C71924100 @default.
• W2034262331 hasConceptScore W2034262331C90924648 @default.
• W2034262331 hasIssue "12" @default.
• W2034262331 hasLocation W20342623311 @default.
• W2034262331 hasLocation W20342623312 @default.
• W2034262331 hasOpenAccess W2034262331 @default.
• W2034262331 hasPrimaryLocation W20342623311 @default.
• W2034262331 hasRelatedWork W1554631561 @default.
• W2034262331 hasRelatedWork W2119038647 @default.
• W2034262331 hasRelatedWork W2326991669 @default.
• W2034262331 hasRelatedWork W2370819829 @default.
• W2034262331 hasRelatedWork W2414308027 @default.
• W2034262331 hasRelatedWork W2425567578 @default.
• W2034262331 hasRelatedWork W2466998296 @default.
• W2034262331 hasRelatedWork W2566367192 @default.
• W2034262331 hasRelatedWork W2791062776 @default.
• W2034262331 hasRelatedWork W3107549865 @default.

• next