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- W2034268110 abstract "The present review highlights adrenal function in the context of endocrine-immune interactions and hypothalamic-pituitary-adrenal (HPA) axis activity in asthmatic children on long-term treatment with inhaled corticosteroids (ICS). Activation of the HPA axis by specific cytokines increases the release of cortisol, which in turn feeds back and suppresses the immune reaction. Reduced responsiveness of the HPA axis in patients with various chronic allergic inflammatory disorders and a blunted HPA axis response of poorly controlled asthmatics before long-term treatment with ICS have been reported. It appears that pro- and anti-inflammatory cytokines may be involved in the attenuation of cortisol and ACTH responses to stress in these patients. ICS as anti-inflammatory agents may have favorable effects in asthmatics with baseline subnormal adrenal responses, thus improving adrenal function during successful long-term treatment; on the other hand, few patients on conventional doses may experience further deterioration of adrenal function, a phenomenon that most likely is genetically determined. When ICS are administered at high doses, secondary adrenal insufficiency due to the excessive exogenous corticosteroid certainly may become manifest." @default.
- W2034268110 created "2016-06-24" @default.
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- W2034268110 creator A5064701946 @default.
- W2034268110 date "2009-01-01" @default.
- W2034268110 modified "2023-10-01" @default.
- W2034268110 title "Endocrine-Immune Interactions in Adrenal Function of Asthmatic Children on Inhaled Corticosteroids" @default.
- W2034268110 cites W1492890516 @default.
- W2034268110 cites W1582446248 @default.
- W2034268110 cites W1599271716 @default.
- W2034268110 cites W1866384779 @default.
- W2034268110 cites W1877755747 @default.
- W2034268110 cites W1963517405 @default.
- W2034268110 cites W1963763550 @default.
- W2034268110 cites W1965298978 @default.
- W2034268110 cites W1969384628 @default.
- W2034268110 cites W1973703676 @default.
- W2034268110 cites W1977968089 @default.
- W2034268110 cites W1986555896 @default.
- W2034268110 cites W1986763093 @default.
- W2034268110 cites W1990142540 @default.
- W2034268110 cites W1991545126 @default.
- W2034268110 cites W1996400629 @default.
- W2034268110 cites W2005444236 @default.
- W2034268110 cites W2007792232 @default.
- W2034268110 cites W2013278352 @default.
- W2034268110 cites W2018175085 @default.
- W2034268110 cites W2020716977 @default.
- W2034268110 cites W2022994831 @default.
- W2034268110 cites W2023717389 @default.
- W2034268110 cites W2026429915 @default.
- W2034268110 cites W2033763265 @default.
- W2034268110 cites W2034625444 @default.
- W2034268110 cites W2044370673 @default.
- W2034268110 cites W2046081479 @default.
- W2034268110 cites W2047217999 @default.
- W2034268110 cites W2048032185 @default.
- W2034268110 cites W2049670746 @default.
- W2034268110 cites W2056885169 @default.
- W2034268110 cites W2061268835 @default.
- W2034268110 cites W2063422274 @default.
- W2034268110 cites W2063511989 @default.
- W2034268110 cites W2066830667 @default.
- W2034268110 cites W2070028366 @default.
- W2034268110 cites W2074953699 @default.
- W2034268110 cites W2076519106 @default.
- W2034268110 cites W2077514608 @default.
- W2034268110 cites W2078914776 @default.
- W2034268110 cites W2090250744 @default.
- W2034268110 cites W2091263563 @default.
- W2034268110 cites W2092793759 @default.
- W2034268110 cites W2092963444 @default.
- W2034268110 cites W2093262590 @default.
- W2034268110 cites W2094437990 @default.
- W2034268110 cites W2108449402 @default.
- W2034268110 cites W2115036418 @default.
- W2034268110 cites W2115261152 @default.
- W2034268110 cites W2119614430 @default.
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- W2034268110 cites W2127988591 @default.
- W2034268110 cites W2132405776 @default.
- W2034268110 cites W2134062936 @default.
- W2034268110 cites W2139148381 @default.
- W2034268110 cites W2144890898 @default.
- W2034268110 cites W2149145601 @default.
- W2034268110 cites W2151937061 @default.
- W2034268110 cites W2155081634 @default.
- W2034268110 cites W2159197384 @default.
- W2034268110 cites W2161126137 @default.
- W2034268110 cites W2162624882 @default.
- W2034268110 cites W2170941055 @default.
- W2034268110 cites W2171155519 @default.
- W2034268110 cites W2171373235 @default.
- W2034268110 cites W2172333031 @default.
- W2034268110 cites W2312314179 @default.
- W2034268110 cites W2320349682 @default.
- W2034268110 cites W2324400354 @default.
- W2034268110 cites W2337334425 @default.
- W2034268110 cites W2340839178 @default.
- W2034268110 cites W2575440738 @default.
- W2034268110 cites W387031605 @default.
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- W2034268110 doi "https://doi.org/10.1159/000216191" @default.
- W2034268110 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19571594" @default.
- W2034268110 hasPublicationYear "2009" @default.
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