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- W2034269462 abstract "Treatment with steroids for short term cluster headache (CH) prophylaxis is a widely accepted therapy. However, the mechanism of action of steroids in CH prophylaxis is unknown. Various studies could show that the trigeminovascular system and the hypothalamus play probably a key role in CH pathophysiology. The neuropeptid calcitonin gene related peptide (CGRP) is released in an acute attack indicating activation of the trigeminovasclular system.[1] The hypothalamus regulates the circadian secretion of melatonin which is reduced in CH patients during a bout.[2]" @default.
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- W2034269462 date "2013-02-01" @default.
- W2034269462 modified "2023-10-14" @default.
- W2034269462 title "Methyprednisolone i.v. alters levels of CGRP and melatonin in cluster headache patients" @default.
- W2034269462 cites W2057590372 @default.
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- W2034269462 doi "https://doi.org/10.1186/1129-2377-14-s1-p63" @default.
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