FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034272617> ?p ?o ?g. }

• W2034272617 endingPage "278" @default.
• W2034272617 startingPage "267" @default.
• W2034272617 abstract "Streptococcus pneumoniae attach to human pharyngeal epithelial cells through the specific interaction of bacterial surface adhesins with glycoconjugate receptors. The present study defines the adhesin as a molecule bridging between an anchoring site in the bacterial cell wall and the epithelial cell receptor. The nature of the adhesin was defined in three ways: First, the attachment of whole bacteria was reduced by trypsin, periodate and heat. Second, heat treatment of whole bacteria was shown to release material, which was able to reconstitute the adherence. The heat extract bound to epithelial cells, as shown by fluorescence labelling, and agglutinated latex beads covalently coupled with receptor oligosaccharide. Active material could be extracted by heat from both high and low adhering strains, but could reconstitute only attaching strains. Third, the bacterial component binding the adhesin was localized to protoplasts and cell wall fractions obtained by mechanical or deoxycholate induced lysis of pneumococci. Isolated pneumococcal surface components, which did not inhibit attachment, included peptidoglycan, C polysaccharide, Forssmann antigen, capsular polysaccharide and a phenol extract produced in analogy to streptococcal lipoteichoic acid. The procedure used to extract the adhesin was previously used to prepare the competence factor. The competence deficient mutant RA7- attached poorly compared to the competent R6 parent. The possible relatedness of attachment to competence is discussed." @default.
• W2034272617 created "2016-06-24" @default.
• W2034272617 creator A5004233255 @default.
• W2034272617 creator A5036791262 @default.
• W2034272617 creator A5068262375 @default.
• W2034272617 creator A5068812282 @default.
• W2034272617 creator A5081757054 @default.
• W2034272617 date "1988-04-01" @default.
• W2034272617 modified "2023-09-25" @default.
• W2034272617 title "A sandwich adhesin on Streptococcus pneumoniae attaching to human oropharyngeal epithelial cells in vitro" @default.
• W2034272617 cites W1531333447 @default.
• W2034272617 cites W1595078087 @default.
• W2034272617 cites W1602540795 @default.
• W2034272617 cites W1664802995 @default.
• W2034272617 cites W1665655905 @default.
• W2034272617 cites W1849497383 @default.
• W2034272617 cites W1854736465 @default.
• W2034272617 cites W1876891435 @default.
• W2034272617 cites W1969644739 @default.
• W2034272617 cites W1994783729 @default.
• W2034272617 cites W2054298981 @default.
• W2034272617 cites W2055942406 @default.
• W2034272617 cites W2072424528 @default.
• W2034272617 cites W2075909846 @default.
• W2034272617 cites W2086281512 @default.
• W2034272617 cites W2087298783 @default.
• W2034272617 cites W2090152223 @default.
• W2034272617 cites W2114489623 @default.
• W2034272617 cites W2129958874 @default.
• W2034272617 cites W2141303544 @default.
• W2034272617 cites W2160645055 @default.
• W2034272617 doi "https://doi.org/10.1016/0882-4010(88)90087-3" @default.
• W2034272617 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2849030" @default.
• W2034272617 hasPublicationYear "1988" @default.
• W2034272617 type Work @default.
• W2034272617 sameAs 2034272617 @default.
• W2034272617 citedByCount "32" @default.
• W2034272617 countsByYear W20342726172012 @default.
• W2034272617 countsByYear W20342726172014 @default.
• W2034272617 crossrefType "journal-article" @default.
• W2034272617 hasAuthorship W2034272617A5004233255 @default.
• W2034272617 hasAuthorship W2034272617A5036791262 @default.
• W2034272617 hasAuthorship W2034272617A5068262375 @default.
• W2034272617 hasAuthorship W2034272617A5068812282 @default.
• W2034272617 hasAuthorship W2034272617A5081757054 @default.
• W2034272617 hasConcept C104317684 @default.
• W2034272617 hasConcept C125235067 @default.
• W2034272617 hasConcept C13426554 @default.
• W2034272617 hasConcept C179470777 @default.
• W2034272617 hasConcept C2776634448 @default.
• W2034272617 hasConcept C2778253522 @default.
• W2034272617 hasConcept C2779489039 @default.
• W2034272617 hasConcept C2781253189 @default.
• W2034272617 hasConcept C39103817 @default.
• W2034272617 hasConcept C501593827 @default.
• W2034272617 hasConcept C523546767 @default.
• W2034272617 hasConcept C54355233 @default.
• W2034272617 hasConcept C547475151 @default.
• W2034272617 hasConcept C55493867 @default.
• W2034272617 hasConcept C6977687 @default.
• W2034272617 hasConcept C86803240 @default.
• W2034272617 hasConcept C89423630 @default.
• W2034272617 hasConceptScore W2034272617C104317684 @default.
• W2034272617 hasConceptScore W2034272617C125235067 @default.
• W2034272617 hasConceptScore W2034272617C13426554 @default.
• W2034272617 hasConceptScore W2034272617C179470777 @default.
• W2034272617 hasConceptScore W2034272617C2776634448 @default.
• W2034272617 hasConceptScore W2034272617C2778253522 @default.
• W2034272617 hasConceptScore W2034272617C2779489039 @default.
• W2034272617 hasConceptScore W2034272617C2781253189 @default.
• W2034272617 hasConceptScore W2034272617C39103817 @default.
• W2034272617 hasConceptScore W2034272617C501593827 @default.
• W2034272617 hasConceptScore W2034272617C523546767 @default.
• W2034272617 hasConceptScore W2034272617C54355233 @default.
• W2034272617 hasConceptScore W2034272617C547475151 @default.
• W2034272617 hasConceptScore W2034272617C55493867 @default.
• W2034272617 hasConceptScore W2034272617C6977687 @default.
• W2034272617 hasConceptScore W2034272617C86803240 @default.
• W2034272617 hasConceptScore W2034272617C89423630 @default.
• W2034272617 hasIssue "4" @default.
• W2034272617 hasLocation W20342726171 @default.
• W2034272617 hasLocation W20342726172 @default.
• W2034272617 hasOpenAccess W2034272617 @default.
• W2034272617 hasPrimaryLocation W20342726171 @default.
• W2034272617 hasRelatedWork W106869129 @default.
• W2034272617 hasRelatedWork W1677970242 @default.
• W2034272617 hasRelatedWork W1990872364 @default.
• W2034272617 hasRelatedWork W2079222412 @default.
• W2034272617 hasRelatedWork W2108152766 @default.
• W2034272617 hasRelatedWork W2405126376 @default.
• W2034272617 hasRelatedWork W2772532446 @default.
• W2034272617 hasRelatedWork W2799244929 @default.
• W2034272617 hasRelatedWork W2951131666 @default.
• W2034272617 hasRelatedWork W47526678 @default.
• W2034272617 hasVolume "4" @default.
• W2034272617 isParatext "false" @default.
• W2034272617 isRetracted "false" @default.
• W2034272617 magId "2034272617" @default.

• next