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- W2034273640 abstract "There has been considerable evidence that, aside from various other effects, synthetic anticholinergics also possess a significant euphoriant property. A double-blind placebo-controlled study was conducted in an attempt to answer the following questions: Can euphoria be induced by experimental intravenous administration of biperiden in therapeutic dosages? Is the individual's psychic response to anticholinergics associated with particular personality traits? In a study with a double-blind placebo cross-over design 28 healthy volunteers were given biperiden intravenously. The evaluation of their reaction to the drug using the Bech-Rafaelsen Mania Scale (MRS) revealed two groups of about the same numerical size demonstrating a considerable difference in their reaction to the drug." @default.
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- W2034273640 date "1987-03-01" @default.
- W2034273640 modified "2023-09-27" @default.
- W2034273640 title "Mood-altering effects of biperiden in healthy volunteers" @default.
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- W2034273640 doi "https://doi.org/10.1016/0165-0327(87)90008-5" @default.
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