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- W2034276346 abstract "Palmoplantar keratoderma (PPK) represents a heterogenous group of disorders characterized by diffuse hyperkeratosis of the palms and soles. 1 Tropet Y. Zultak M. Blanc D. Laurent R. Vichard P. Surgical treatment of epidermolytic hereditary palmoplantar keratoderma. J Hand Surg Am. Jan 1989; 14: 143-149 Abstract Full Text PDF PubMed Scopus (7) Google Scholar Described in 1924, PLS represents a constellation of disorders characterized by diffuse palmoplantar hyperkeratosis and rapidly progressing periodontitis of primary and permanent dentation, resulting from an autosomal recessive point mutation in the cathepsin C gene. Incidence ranges from 1 to 4 per million worldwide, with more than 300 cases reported. Treatment of Papillon–Lefevre Syndrome (PLS) involves aggressive periodontal treatment, including prophylactic teeth excision and titanium implants in addition to symptomatic treatment of involved palms and plantar foot (Figures 1 and 2). Figure 2Right foot plantar view of some keratotic recurrence in patient with Papillon–Lefevre Syndrome after excision, bovine collagen, and skin grafts at 18 month follow up visit. Patient is now ambulatory after 10 years of being wheelchair bound secondary to pain. View Large Image Figure Viewer Download Hi-res image" @default.
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- W2034276346 date "2013-12-01" @default.
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- W2034276346 title "Surgical treatment of Papillon–Lefèvre Syndrome with bovine collagen and skin graft" @default.
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