FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034279013> ?p ?o ?g. }

• W2034279013 endingPage "2043" @default.
• W2034279013 startingPage "2035" @default.
• W2034279013 abstract "To aid the development of symptomatic and disease modifying therapies in Parkinson's disease (PD), there is a strong need to identify noninvasive measures of basal ganglia (BG) function that are sensitive to disease severity. This study examines the relation between blood oxygenation level-dependent (BOLD) activation in every nucleus of the BG and symptom-specific disease severity in early stage de novo PD. BOLD activation measured at 3 T was compared between 20 early stage de novo PD patients and 20 controls during an established precision grip force task. In addition to the BG nuclei, activation in specific thalamic and cortical regions was examined. There were three novel findings. First, there were significant negative correlations between total motor Unified PD Rating Scale and BOLD activation in bilateral caudate, bilateral putamen, contralateral external segment of the globus pallidus, bilateral subthalamic nucleus, contralateral substantia nigra, and thalamus. Second, bradykinesia was the symptom that most consistently predicted BOLD activation in the BG and thalamus. Also, BOLD activation in the contralateral internal globus pallidus was related to tremor. Third, the reduced cortical activity in primary motor cortex and supplementary motor area in de novo PD did not relate to motor symptoms. These findings demonstrate that BOLD activity in nuclei of the BG relates most consistently to bradykinesia and functional magnetic resonance imaging has strong potential to serve as a noninvasive marker for the state of BG function in de novo PD." @default.
• W2034279013 created "2016-06-24" @default.
• W2034279013 creator A5019592840 @default.
• W2034279013 creator A5027915928 @default.
• W2034279013 creator A5048592948 @default.
• W2034279013 creator A5062212464 @default.
• W2034279013 creator A5071580456 @default.
• W2034279013 date "2010-08-19" @default.
• W2034279013 modified "2023-10-15" @default.
• W2034279013 title "Blood oxygenation level-dependent activation in basal ganglia nuclei relates to specific symptoms in de novo Parkinson's disease" @default.
• W2034279013 cites W1974038177 @default.
• W2034279013 cites W1977655392 @default.
• W2034279013 cites W1984414718 @default.
• W2034279013 cites W2008560062 @default.
• W2034279013 cites W2015749893 @default.
• W2034279013 cites W2031170841 @default.
• W2034279013 cites W2031547184 @default.
• W2034279013 cites W2031799317 @default.
• W2034279013 cites W2038618926 @default.
• W2034279013 cites W2048781224 @default.
• W2034279013 cites W2061376322 @default.
• W2034279013 cites W2068444583 @default.
• W2034279013 cites W2072572621 @default.
• W2034279013 cites W2094876440 @default.
• W2034279013 cites W2117277050 @default.
• W2034279013 cites W2118613970 @default.
• W2034279013 cites W2129167248 @default.
• W2034279013 cites W2130226832 @default.
• W2034279013 cites W2139474536 @default.
• W2034279013 cites W2143747410 @default.
• W2034279013 cites W2147041299 @default.
• W2034279013 cites W2159132478 @default.
• W2034279013 doi "https://doi.org/10.1002/mds.23360" @default.
• W2034279013 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2952037" @default.
• W2034279013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20725915" @default.
• W2034279013 hasPublicationYear "2010" @default.
• W2034279013 type Work @default.
• W2034279013 sameAs 2034279013 @default.
• W2034279013 citedByCount "57" @default.
• W2034279013 countsByYear W20342790132012 @default.
• W2034279013 countsByYear W20342790132013 @default.
• W2034279013 countsByYear W20342790132014 @default.
• W2034279013 countsByYear W20342790132015 @default.
• W2034279013 countsByYear W20342790132016 @default.
• W2034279013 countsByYear W20342790132017 @default.
• W2034279013 countsByYear W20342790132018 @default.
• W2034279013 countsByYear W20342790132019 @default.
• W2034279013 countsByYear W20342790132020 @default.
• W2034279013 countsByYear W20342790132022 @default.
• W2034279013 countsByYear W20342790132023 @default.
• W2034279013 crossrefType "journal-article" @default.
• W2034279013 hasAuthorship W2034279013A5019592840 @default.
• W2034279013 hasAuthorship W2034279013A5027915928 @default.
• W2034279013 hasAuthorship W2034279013A5048592948 @default.
• W2034279013 hasAuthorship W2034279013A5062212464 @default.
• W2034279013 hasAuthorship W2034279013A5071580456 @default.
• W2034279013 hasBestOaLocation W20342790132 @default.
• W2034279013 hasConcept C126322002 @default.
• W2034279013 hasConcept C15744967 @default.
• W2034279013 hasConcept C169760540 @default.
• W2034279013 hasConcept C2777319143 @default.
• W2034279013 hasConcept C2778187257 @default.
• W2034279013 hasConcept C2778542668 @default.
• W2034279013 hasConcept C2779134260 @default.
• W2034279013 hasConcept C2779226451 @default.
• W2034279013 hasConcept C2779246727 @default.
• W2034279013 hasConcept C2779714222 @default.
• W2034279013 hasConcept C2779734285 @default.
• W2034279013 hasConcept C2780278869 @default.
• W2034279013 hasConcept C2780938664 @default.
• W2034279013 hasConcept C2781423529 @default.
• W2034279013 hasConcept C529278444 @default.
• W2034279013 hasConcept C71924100 @default.
• W2034279013 hasConceptScore W2034279013C126322002 @default.
• W2034279013 hasConceptScore W2034279013C15744967 @default.
• W2034279013 hasConceptScore W2034279013C169760540 @default.
• W2034279013 hasConceptScore W2034279013C2777319143 @default.
• W2034279013 hasConceptScore W2034279013C2778187257 @default.
• W2034279013 hasConceptScore W2034279013C2778542668 @default.
• W2034279013 hasConceptScore W2034279013C2779134260 @default.
• W2034279013 hasConceptScore W2034279013C2779226451 @default.
• W2034279013 hasConceptScore W2034279013C2779246727 @default.
• W2034279013 hasConceptScore W2034279013C2779714222 @default.
• W2034279013 hasConceptScore W2034279013C2779734285 @default.
• W2034279013 hasConceptScore W2034279013C2780278869 @default.
• W2034279013 hasConceptScore W2034279013C2780938664 @default.
• W2034279013 hasConceptScore W2034279013C2781423529 @default.
• W2034279013 hasConceptScore W2034279013C529278444 @default.
• W2034279013 hasConceptScore W2034279013C71924100 @default.
• W2034279013 hasFunder F4320332161 @default.
• W2034279013 hasIssue "13" @default.
• W2034279013 hasLocation W20342790131 @default.
• W2034279013 hasLocation W20342790132 @default.
• W2034279013 hasLocation W20342790133 @default.
• W2034279013 hasLocation W20342790134 @default.
• W2034279013 hasOpenAccess W2034279013 @default.
• W2034279013 hasPrimaryLocation W20342790131 @default.
• W2034279013 hasRelatedWork W136845267 @default.

• next