FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034281709> ?p ?o ?g. }

• W2034281709 endingPage "61" @default.
• W2034281709 startingPage "56" @default.
• W2034281709 abstract "Oxidative stress and reperfusion injury may develop in different ischemia–reperfusion (IR) models. Growing evidence links altered lipid protein redox-homeostasis with IR. The effect of fluoxetine (FLX; N-methyl-3-[4-(trifluoromethyl) phenoxy] benzenepropanamine), on the lipid protein redox-homeostasis mechanisms in the rats exposed to aortic IR is unclear. We aimed to investigate the effects of FLX on circulating protein oxidation and lipid peroxidation parameters, such as ischemia modified albumin (IMA), lipid hydroperoxide (LOOH), prooxidant antioxidant balance (PAB), erythrocyte glutathione (GSH), CuZn-superoxide dismutase (CuZn-SOD), ferric reducing antioxidant power (FRAP), as potential IR biomarkers. Wistar rats were randomized into three groups (n=7/group): 1) Control (sham laparotomy); 2) IR without FLX, (60 min ischemia and 120 min reperfusion); 3) IR with FLX (FLX+IR) (FLX 20 mg/kg/day, i.p. for three days before surgery). All of the aforementioned parameters (IMA, LOOH, PAB, GSH, CuZn-SOD, and FRAP) were measured spectrophotometrically. IMA, LOOH, and PAB levels in IR group were significantly higher than the control (P<0.01 respectively) and fluoxetine groups (P<0.01, P<0.01, and P<0.05 respectively), whereas CuZn-SOD activities, GSH and FRAP were significantly lower in IR groups. Fluoxetine group significantly reduced IMA when compared to IR group (P<0.001) and control group (P<0.01). With respect to IMA, LOOH and PAB, impaired redox homeostasis is substantially more prominent in aortic IR. The antidepressant FLX has profitable effects on circulating redox status in rats exposed to aortic IR. FLX administration before IR might decrease the surgery-enhanced free radical production; taken together, the antioxidant effects of FLX supplementation should be considered in future studies." @default.
• W2034281709 created "2016-06-24" @default.
• W2034281709 creator A5009750768 @default.
• W2034281709 creator A5035449399 @default.
• W2034281709 creator A5044155121 @default.
• W2034281709 creator A5052805451 @default.
• W2034281709 creator A5064613492 @default.
• W2034281709 creator A5078330186 @default.
• W2034281709 creator A5081521791 @default.
• W2034281709 creator A5084965864 @default.
• W2034281709 creator A5091882365 @default.
• W2034281709 date "2015-02-01" @default.
• W2034281709 modified "2023-10-01" @default.
• W2034281709 title "The effects of fluoxetine on circulating oxidative damage parameters in rats exposed to aortic ischemia–reperfusion" @default.
• W2034281709 cites W1502932546 @default.
• W2034281709 cites W1532672888 @default.
• W2034281709 cites W1576670477 @default.
• W2034281709 cites W1934994215 @default.
• W2034281709 cites W1939635274 @default.
• W2034281709 cites W1963759139 @default.
• W2034281709 cites W1971291382 @default.
• W2034281709 cites W1973888688 @default.
• W2034281709 cites W1977657096 @default.
• W2034281709 cites W1982360670 @default.
• W2034281709 cites W1987785379 @default.
• W2034281709 cites W1992411493 @default.
• W2034281709 cites W2000947149 @default.
• W2034281709 cites W2002838882 @default.
• W2034281709 cites W2007663048 @default.
• W2034281709 cites W2016462339 @default.
• W2034281709 cites W2024077773 @default.
• W2034281709 cites W2025039190 @default.
• W2034281709 cites W2030072622 @default.
• W2034281709 cites W2042400897 @default.
• W2034281709 cites W2055517339 @default.
• W2034281709 cites W2056278557 @default.
• W2034281709 cites W2057817179 @default.
• W2034281709 cites W2064029312 @default.
• W2034281709 cites W2064519572 @default.
• W2034281709 cites W2065043991 @default.
• W2034281709 cites W2065076024 @default.
• W2034281709 cites W2065702891 @default.
• W2034281709 cites W2066927369 @default.
• W2034281709 cites W2067230717 @default.
• W2034281709 cites W2073909062 @default.
• W2034281709 cites W2074602237 @default.
• W2034281709 cites W2076371251 @default.
• W2034281709 cites W2103924942 @default.
• W2034281709 cites W2111981306 @default.
• W2034281709 cites W2112765981 @default.
• W2034281709 cites W2159305277 @default.
• W2034281709 cites W2166306701 @default.
• W2034281709 cites W2184869047 @default.
• W2034281709 cites W2326642390 @default.
• W2034281709 cites W2976170744 @default.
• W2034281709 cites W3026330180 @default.
• W2034281709 doi "https://doi.org/10.1016/j.ejphar.2015.01.007" @default.
• W2034281709 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25595729" @default.
• W2034281709 hasPublicationYear "2015" @default.
• W2034281709 type Work @default.
• W2034281709 sameAs 2034281709 @default.
• W2034281709 citedByCount "9" @default.
• W2034281709 countsByYear W20342817092015 @default.
• W2034281709 countsByYear W20342817092016 @default.
• W2034281709 countsByYear W20342817092018 @default.
• W2034281709 countsByYear W20342817092019 @default.
• W2034281709 countsByYear W20342817092020 @default.
• W2034281709 countsByYear W20342817092021 @default.
• W2034281709 countsByYear W20342817092022 @default.
• W2034281709 crossrefType "journal-article" @default.
• W2034281709 hasAuthorship W2034281709A5009750768 @default.
• W2034281709 hasAuthorship W2034281709A5035449399 @default.
• W2034281709 hasAuthorship W2034281709A5044155121 @default.
• W2034281709 hasAuthorship W2034281709A5052805451 @default.
• W2034281709 hasAuthorship W2034281709A5064613492 @default.
• W2034281709 hasAuthorship W2034281709A5078330186 @default.
• W2034281709 hasAuthorship W2034281709A5081521791 @default.
• W2034281709 hasAuthorship W2034281709A5084965864 @default.
• W2034281709 hasAuthorship W2034281709A5091882365 @default.
• W2034281709 hasConcept C126322002 @default.
• W2034281709 hasConcept C134018914 @default.
• W2034281709 hasConcept C181199279 @default.
• W2034281709 hasConcept C185592680 @default.
• W2034281709 hasConcept C2775838275 @default.
• W2034281709 hasConcept C2776151105 @default.
• W2034281709 hasConcept C2778004101 @default.
• W2034281709 hasConcept C2778401633 @default.
• W2034281709 hasConcept C2780829032 @default.
• W2034281709 hasConcept C538909803 @default.
• W2034281709 hasConcept C541997718 @default.
• W2034281709 hasConcept C55493867 @default.
• W2034281709 hasConcept C63645605 @default.
• W2034281709 hasConcept C71924100 @default.
• W2034281709 hasConcept C98274493 @default.
• W2034281709 hasConceptScore W2034281709C126322002 @default.
• W2034281709 hasConceptScore W2034281709C134018914 @default.
• W2034281709 hasConceptScore W2034281709C181199279 @default.
• W2034281709 hasConceptScore W2034281709C185592680 @default.

• next