FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034282255> ?p ?o ?g. }

• W2034282255 abstract "You have accessJournal of UrologyProstate Cancer: Advanced II1 Apr 2012773 PROSPECTIVE EVALUATION OF THE EARLY IMPACT OF THE LHRH ANALOGUES, IN THE TREATMENT OF PROSTATE CANCER, IN SEXUAL, PSYCHO-COGNITIVE, EMOTIONAL AND QUALITY OF LIFE PARAMETERS Alfredo Rodríguez, Javier Romero, Borja Garcia, Felix Guerrero, Angeles Cabeza, Maria Clavel, Beatriz Mugica, Eduardo Lanzos, and Rafael Diaz Alfredo RodríguezAlfredo Rodríguez Madrid, Spain More articles by this author , Javier RomeroJavier Romero Madrid, Spain More articles by this author , Borja GarciaBorja Garcia Madrid, Spain More articles by this author , Felix GuerreroFelix Guerrero Madrid, Spain More articles by this author , Angeles CabezaAngeles Cabeza Madrid, Spain More articles by this author , Maria ClavelMaria Clavel Madrid, Spain More articles by this author , Beatriz MugicaBeatriz Mugica Madrid, Spain More articles by this author , Eduardo LanzosEduardo Lanzos Madrid, Spain More articles by this author , and Rafael DiazRafael Diaz Madrid, Spain More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2012.02.860AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The castration with LHRH agonists (LHRHa) in the control of the prostate cancer (PC) is associated with a wide spectrum of body, metabolic, sexual and psycho-cognitive alterations. Nowadays it is still not well documented the time to develop and the severity of these changes. We are developing a study to evaluate which, the moment and the severity of appearance of these modifications. METHODS Unique institution prospective and descriptive study. IRB approval. Study population: High risk PC patients submitted to radiotherapy and long period adjuvant hormonotherapy with LHRHa. Included consecutively from September 2009 to January 2011. To evaluate the symptoms 5 validated questionnaires were administered: baseline and 3, 6, 12, 24 and 36 months after therapy start: 1. International Index Erectile Function (IIEF): sexual modifications; 2. Aging Males' Symptoms Scale (AMSS): androgenic deficit, 3. Minimental test (MM): Cognitive area, 4. Short Form Health Survey SF-12 : Quality of life; 5. Beck Depression Inventory (BDI) Mental status and depression. Data were analyzed with the Wilcoxon test with a statistical significance p value < 0,05. RESULTS 61 patients were available at 6 months at least evaluation. The IIEF shows: a dramatic decrease since the first evaluation (p<0,05). AMSS test shows a progressive worsening (28, 32, 33 points at 6 months) (p <0,05). The MM test (cognitive area) does not demonstrate any significant alteration. SF-12 test (mental health area) shows a deterioration after 6 months (p=0,03). The rest of evaluated parameters do not present modifications. A deterioration in the BDI test (depresion area) is observed from the baseline (3,5 points) to the 3 months evaluation (4,9 points) (p=0,08), that consolidates at the 6 months (5,8 points) (p=0,030). CONCLUSIONS Treatment with LHRHa shows from initial stages (3 months) deleterious effects, fundamentally in the sexual sphere. At 6 months a slight deterioration of the mental status appears, which is confirmed in the paragraph of mental health when we evaluate the quality of life. Neither the cognitive capacity, nor the rest of quality parameters of global life seem to be diminished at this early period of time. © 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 187Issue 4SApril 2012Page: e315-e316 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.MetricsAuthor Information Alfredo Rodríguez Madrid, Spain More articles by this author Javier Romero Madrid, Spain More articles by this author Borja Garcia Madrid, Spain More articles by this author Felix Guerrero Madrid, Spain More articles by this author Angeles Cabeza Madrid, Spain More articles by this author Maria Clavel Madrid, Spain More articles by this author Beatriz Mugica Madrid, Spain More articles by this author Eduardo Lanzos Madrid, Spain More articles by this author Rafael Diaz Madrid, Spain More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ..." @default.
• W2034282255 created "2016-06-24" @default.
• W2034282255 creator A5008137528 @default.
• W2034282255 creator A5027563077 @default.
• W2034282255 creator A5031707390 @default.
• W2034282255 creator A5034655528 @default.
• W2034282255 creator A5053866213 @default.
• W2034282255 creator A5055316364 @default.
• W2034282255 creator A5057552886 @default.
• W2034282255 creator A5069248161 @default.
• W2034282255 creator A5070578967 @default.
• W2034282255 date "2012-04-01" @default.
• W2034282255 modified "2023-09-26" @default.
• W2034282255 title "773 PROSPECTIVE EVALUATION OF THE EARLY IMPACT OF THE LHRH ANALOGUES, IN THE TREATMENT OF PROSTATE CANCER, IN SEXUAL, PSYCHO-COGNITIVE, EMOTIONAL AND QUALITY OF LIFE PARAMETERS" @default.
• W2034282255 doi "https://doi.org/10.1016/j.juro.2012.02.860" @default.
• W2034282255 hasPublicationYear "2012" @default.
• W2034282255 type Work @default.
• W2034282255 sameAs 2034282255 @default.
• W2034282255 citedByCount "0" @default.
• W2034282255 crossrefType "journal-article" @default.
• W2034282255 hasAuthorship W2034282255A5008137528 @default.
• W2034282255 hasAuthorship W2034282255A5027563077 @default.
• W2034282255 hasAuthorship W2034282255A5031707390 @default.
• W2034282255 hasAuthorship W2034282255A5034655528 @default.
• W2034282255 hasAuthorship W2034282255A5053866213 @default.
• W2034282255 hasAuthorship W2034282255A5055316364 @default.
• W2034282255 hasAuthorship W2034282255A5057552886 @default.
• W2034282255 hasAuthorship W2034282255A5069248161 @default.
• W2034282255 hasAuthorship W2034282255A5070578967 @default.
• W2034282255 hasConcept C121608353 @default.
• W2034282255 hasConcept C126322002 @default.
• W2034282255 hasConcept C142362112 @default.
• W2034282255 hasConcept C15708023 @default.
• W2034282255 hasConcept C159110408 @default.
• W2034282255 hasConcept C188816634 @default.
• W2034282255 hasConcept C2776684731 @default.
• W2034282255 hasConcept C2779951463 @default.
• W2034282255 hasConcept C2780192828 @default.
• W2034282255 hasConcept C2908647359 @default.
• W2034282255 hasConcept C29456083 @default.
• W2034282255 hasConcept C71924100 @default.
• W2034282255 hasConcept C74909509 @default.
• W2034282255 hasConcept C99454951 @default.
• W2034282255 hasConceptScore W2034282255C121608353 @default.
• W2034282255 hasConceptScore W2034282255C126322002 @default.
• W2034282255 hasConceptScore W2034282255C142362112 @default.
• W2034282255 hasConceptScore W2034282255C15708023 @default.
• W2034282255 hasConceptScore W2034282255C159110408 @default.
• W2034282255 hasConceptScore W2034282255C188816634 @default.
• W2034282255 hasConceptScore W2034282255C2776684731 @default.
• W2034282255 hasConceptScore W2034282255C2779951463 @default.
• W2034282255 hasConceptScore W2034282255C2780192828 @default.
• W2034282255 hasConceptScore W2034282255C2908647359 @default.
• W2034282255 hasConceptScore W2034282255C29456083 @default.
• W2034282255 hasConceptScore W2034282255C71924100 @default.
• W2034282255 hasConceptScore W2034282255C74909509 @default.
• W2034282255 hasConceptScore W2034282255C99454951 @default.
• W2034282255 hasIssue "4S" @default.
• W2034282255 hasLocation W20342822551 @default.
• W2034282255 hasOpenAccess W2034282255 @default.
• W2034282255 hasPrimaryLocation W20342822551 @default.
• W2034282255 hasRelatedWork W1984684443 @default.
• W2034282255 hasRelatedWork W2091020218 @default.
• W2034282255 hasRelatedWork W2135329844 @default.
• W2034282255 hasRelatedWork W2295722933 @default.
• W2034282255 hasRelatedWork W2752094163 @default.
• W2034282255 hasRelatedWork W2789448498 @default.
• W2034282255 hasRelatedWork W3098066378 @default.
• W2034282255 hasRelatedWork W34268350 @default.
• W2034282255 hasRelatedWork W69006472 @default.
• W2034282255 hasRelatedWork W4213392682 @default.
• W2034282255 hasVolume "187" @default.
• W2034282255 isParatext "false" @default.
• W2034282255 isRetracted "false" @default.
• W2034282255 magId "2034282255" @default.
• W2034282255 workType "article" @default.