FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034287796> ?p ?o ?g. }

• W2034287796 endingPage "e0116491" @default.
• W2034287796 startingPage "e0116491" @default.
• W2034287796 abstract "Fourier Transform Infrared (FTIR) micro-spectroscopy is an emerging technique for the biochemical analysis of tissues and cellular materials. It provides objective information on the holistic biochemistry of a cell or tissue sample and has been applied in many areas of medical research. However, it has become apparent that how the tissue is handled prior to FTIR micro-spectroscopic imaging requires special consideration, particularly with regards to methods for preservation of the samples. We have performed FTIR micro-spectroscopy on rodent heart and liver tissue sections (two spectroscopically very different biological tissues) that were prepared by desiccation drying, ethanol substitution and formalin fixation and have compared the resulting spectra with that of fully hydrated freshly excised tissues. We have systematically examined the spectra for any biochemical changes to the native state of the tissue caused by the three methods of preparation and have detected changes in infrared (IR) absorption band intensities and peak positions. In particular, the position and profile of the amide I, key in assigning protein secondary structure, changes depending on preparation method and the lipid absorptions lose intensity drastically when these tissues are hydrated with ethanol. Indeed, we demonstrate that preserving samples through desiccation drying, ethanol substitution or formalin fixation significantly alters the biochemical information detected using spectroscopic methods when compared to spectra of fresh hydrated tissue. It is therefore imperative to consider tissue preparative effects when preparing, measuring, and analyzing samples using FTIR spectroscopy." @default.
• W2034287796 created "2016-06-24" @default.
• W2034287796 creator A5008592284 @default.
• W2034287796 creator A5023457100 @default.
• W2034287796 creator A5023680002 @default.
• W2034287796 creator A5044253971 @default.
• W2034287796 creator A5048609668 @default.
• W2034287796 creator A5079194862 @default.
• W2034287796 date "2015-02-24" @default.
• W2034287796 modified "2023-09-30" @default.
• W2034287796 title "Importance of Tissue Preparation Methods in FTIR Micro-Spectroscopical Analysis of Biological Tissues: ‘Traps for New Users’" @default.
• W2034287796 cites W187928116 @default.
• W2034287796 cites W1973530781 @default.
• W2034287796 cites W1977615915 @default.
• W2034287796 cites W1978902250 @default.
• W2034287796 cites W1984675243 @default.
• W2034287796 cites W1986846505 @default.
• W2034287796 cites W1987205935 @default.
• W2034287796 cites W1988146527 @default.
• W2034287796 cites W1995007821 @default.
• W2034287796 cites W1996423623 @default.
• W2034287796 cites W1999550833 @default.
• W2034287796 cites W2010331750 @default.
• W2034287796 cites W2015111818 @default.
• W2034287796 cites W2016489506 @default.
• W2034287796 cites W2018663021 @default.
• W2034287796 cites W2019638166 @default.
• W2034287796 cites W2020631531 @default.
• W2034287796 cites W2033700815 @default.
• W2034287796 cites W2036936602 @default.
• W2034287796 cites W2037540104 @default.
• W2034287796 cites W2038334009 @default.
• W2034287796 cites W2038707973 @default.
• W2034287796 cites W2042190518 @default.
• W2034287796 cites W2043681221 @default.
• W2034287796 cites W2061349383 @default.
• W2034287796 cites W2065425384 @default.
• W2034287796 cites W2069243797 @default.
• W2034287796 cites W2073894935 @default.
• W2034287796 cites W2077213409 @default.
• W2034287796 cites W2091797019 @default.
• W2034287796 cites W2101270900 @default.
• W2034287796 cites W2134130921 @default.
• W2034287796 cites W2148135986 @default.
• W2034287796 cites W2167273463 @default.
• W2034287796 cites W2413373612 @default.
• W2034287796 cites W4255889064 @default.
• W2034287796 doi "https://doi.org/10.1371/journal.pone.0116491" @default.
• W2034287796 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4339720" @default.
• W2034287796 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25710811" @default.
• W2034287796 hasPublicationYear "2015" @default.
• W2034287796 type Work @default.
• W2034287796 sameAs 2034287796 @default.
• W2034287796 citedByCount "98" @default.
• W2034287796 countsByYear W20342877962014 @default.
• W2034287796 countsByYear W20342877962015 @default.
• W2034287796 countsByYear W20342877962016 @default.
• W2034287796 countsByYear W20342877962017 @default.
• W2034287796 countsByYear W20342877962018 @default.
• W2034287796 countsByYear W20342877962019 @default.
• W2034287796 countsByYear W20342877962020 @default.
• W2034287796 countsByYear W20342877962021 @default.
• W2034287796 countsByYear W20342877962022 @default.
• W2034287796 countsByYear W20342877962023 @default.
• W2034287796 crossrefType "journal-article" @default.
• W2034287796 hasAuthorship W2034287796A5008592284 @default.
• W2034287796 hasAuthorship W2034287796A5023457100 @default.
• W2034287796 hasAuthorship W2034287796A5023680002 @default.
• W2034287796 hasAuthorship W2034287796A5044253971 @default.
• W2034287796 hasAuthorship W2034287796A5048609668 @default.
• W2034287796 hasAuthorship W2034287796A5079194862 @default.
• W2034287796 hasBestOaLocation W20342877961 @default.
• W2034287796 hasConcept C104317684 @default.
• W2034287796 hasConcept C121332964 @default.
• W2034287796 hasConcept C127413603 @default.
• W2034287796 hasConcept C146249460 @default.
• W2034287796 hasConcept C153642686 @default.
• W2034287796 hasConcept C160892712 @default.
• W2034287796 hasConcept C178790620 @default.
• W2034287796 hasConcept C185592680 @default.
• W2034287796 hasConcept C32891209 @default.
• W2034287796 hasConcept C42360764 @default.
• W2034287796 hasConcept C55493867 @default.
• W2034287796 hasConcept C62520636 @default.
• W2034287796 hasConceptScore W2034287796C104317684 @default.
• W2034287796 hasConceptScore W2034287796C121332964 @default.
• W2034287796 hasConceptScore W2034287796C127413603 @default.
• W2034287796 hasConceptScore W2034287796C146249460 @default.
• W2034287796 hasConceptScore W2034287796C153642686 @default.
• W2034287796 hasConceptScore W2034287796C160892712 @default.
• W2034287796 hasConceptScore W2034287796C178790620 @default.
• W2034287796 hasConceptScore W2034287796C185592680 @default.
• W2034287796 hasConceptScore W2034287796C32891209 @default.
• W2034287796 hasConceptScore W2034287796C42360764 @default.
• W2034287796 hasConceptScore W2034287796C55493867 @default.
• W2034287796 hasConceptScore W2034287796C62520636 @default.
• W2034287796 hasIssue "2" @default.
• W2034287796 hasLocation W20342877961 @default.

• next