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- W2034303726 endingPage "146" @default.
- W2034303726 startingPage "142" @default.
- W2034303726 abstract "Chromosomal translocation t (8;21)(q22;22) is one of the most frequent cytogenetic abnormalities found in acute myeloid leukaemia (AML). It generates the AML1/ETO fusion gene, which itself supports human haematopoietic stem cell self-renewal. However, the mechanism guiding transcription of this chimeric gene remains unclear. In our work, we attempted to shed light on this essential issue. We investigated the promoter from which transcription of the AML1/ETO gene is initiated and defined the three-dimensional structure of the whole rearranged locus." @default.
- W2034303726 created "2016-06-24" @default.
- W2034303726 creator A5014020540 @default.
- W2034303726 creator A5023735846 @default.
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- W2034303726 date "2012-12-01" @default.
- W2034303726 modified "2023-10-14" @default.
- W2034303726 title "Transcription of the AML1/ETO chimera is guided by the P2 promoter of the AML1 gene in the Kasumi-1 cell line" @default.
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- W2034303726 doi "https://doi.org/10.1016/j.gene.2012.09.028" @default.
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