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- W2034304913 endingPage "157" @default.
- W2034304913 startingPage "149" @default.
- W2034304913 abstract "Exercise in children has important health benefits. However, in elite endurance athletes, there is an increased prevalence of exercise-induced bronchoconstriction and airway inflammation. Particularly at risk are those who practice in cold weather, ice rinks, swimming pools, and air pollution. The inflammation is caused by repetitive episodes of hyperventilation of cold, dry air, allergens, or toxins such as chlorine or air pollution. Children may be particularly at risk for lung injury under these conditions because of the immaturity and ongoing development of their lung. However, studies in pediatric athletes and exercising young children are sparse. Epithelial injury associated with hyperventilation of cold, dry air has not been described in children. However, exercise in the presence of air pollution and chlorine is associated with airway injury and the development of asthma in children; the effect appears to be modulated by both atopy and genetic polymorphisms. While management of exercise-induced bronchoconstriction and asthma is well established, there is little data to guide treatment or prevention of remodeling in athletes or inhalational lung injury in children. Studies underscore the need to maintain high levels of air quality. More investigations should be undertaken to better define the natural history, pathophysiology, and treatment of exercise-induced pulmonary inflammation in both elite athletes and exercising children." @default.
- W2034304913 created "2016-06-24" @default.
- W2034304913 creator A5018269166 @default.
- W2034304913 creator A5065040596 @default.
- W2034304913 date "2011-09-01" @default.
- W2034304913 modified "2023-09-27" @default.
- W2034304913 title "Exercise-Induced Lung Disease: Too Much of a Good Thing?" @default.
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