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- W2034307512 abstract "Comprehensive diagnosis of the patient with ischemic heart disease has become a complex process. The clinician can now confirm and extend bedside observations through a variety of laboratory examinations, chief among which are the several techniques of cardiac imaging (1,2). Standard imaging approaches (roentgenography, echocardiography, radionuclide imaging and angiography) permit delineation of cardiac chamber morphology and function, coronary artery anatomy, valvular function and some estimation of regional deficits in myocardial perfusion. The newest methodspositron emission tomography, rapid computed tomography and nuclear magnetic resonance imaging-promise to add hitherto unavailable data on myocardial perfusion, metabolism and tissue characteristics (3). The goal of assessing tissue composition and physiologic state in a noninvasive fashion (“tissue characterization”) has been sought by investigators using ultrasound (4) and, more recently, nuclear magnetic resonance imaging. In this issue of the Journal, Vered and coworkers (5) present clinical evidence that one particular ultrasound method identifies regions of scar related to previous myocardial infarction. In the current era of aggressive intervention in acute ischemia, the ability to identify collagenous (hence, nonviable) myocardium would be of obvious importance. In this brief editorial, I will highlight the investigative field of ultrasound tissue characterization and attempt to put the current study into a clinical perspective. Noninvasive cardiac tissue characterization. Although current diagnostic methods permit assessment of coronary" @default.
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- W2034307512 title "Ultrasound tissue characterization: Can the state of the myocardium be assessed directly yet noninvasively?" @default.
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- W2034307512 doi "https://doi.org/10.1016/0735-1097(89)90554-8" @default.
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