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• W2034307897 abstract "Abstract White mural thrombosis has been very rarely observed in the rabbit's aorta in experimental cholesterol atherosclerosis. Apparently cholesterol atherosclerosis by itself is not the appropriate damage or alteration required to trigger or initiate thrombosis in rabbits. It appeared to be of interest to determine if the hyperlipidemic state of the rabbit fed cholesterol could modify the amount of white thrombus formed after thrombosis was initiated by insertion of a standard length of polyethylene tube into the abdominal aorta. Twenty rabbits fed 0.5 gm cholesterol per day for 24 days developed severe hyperlipidemia. Polyethylene tubes were inserted into their abdominal aortae on the 24th day and rabbits were sacrificed on the 28th day. In this group, 61.1 mg ± 17.1 S.D. fresh wet weight of white thrombus or 17.0 mg ± 4.6 S.D. freeze-dried weight were found. In comparison, 20 normolipidemic control rabbits showed 67.2 mg ± 4.6 S.D. fresh weight or 15.7 ± 8.8 freeze-dried weight (P > 0.5). It is concluded that hypercholesterolemia induced by feeding cholesterol to rabbits does not modify the amount of white thrombus induced to form by a foreign plastic surface." @default.
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• W2034307897 date "1973-05-01" @default.
• W2034307897 modified "2023-09-27" @default.
• W2034307897 title "Effect of hypercholesterolemia on thrombosis in rabbits" @default.
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• W2034307897 doi "https://doi.org/10.1016/0049-3848(73)90097-2" @default.
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