FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034308986> ?p ?o ?g. }

• W2034308986 endingPage "716" @default.
• W2034308986 startingPage "705" @default.
• W2034308986 abstract "1. Endogenous nitric oxide has been proposed to play a role in the control of myometrial contractility in pregnancy. In this study, the expression, localisation and regulation of nitric oxide synthase (NOS) isoforms have been examined in human pregnant myometrium and cultured human myometrial smooth muscle cells, by immunoblotting, immunohistochemistry and reverse transcription-polymerase chain reaction. 2. Immunoblotting of extracts from freshly isolated myometrial tissue, affinity-enriched for NOS proteins by precipitation with ADP-sepharose, revealed expression of endothelial NOS (eNOS or NOS3) in tissues from preterm, term non-labour and active labour at term. Inducible NOS (iNOS or NOS2) and neuronal NOS (nNOS or NOS1) proteins were not detected at any stage of pregnancy. 3. Immunohistochemical detection showed that expression of eNOS protein was restricted to the endothelium of the myometrial vasculature, with no staining detected in myometrial smooth muscle cells. 4. Messenger RNA for all three NOS isoforms was detected, although iNOS and nNOS mRNAs were detectable only with high cycle number, implying a low copy number. 5. NOS isoforms were not detectable in human myometrial smooth muscle cells cultured from term non-labour pregnancies. Cytokine stimulation of cultured myometrial cells did not induce iNOS expression or nitrite accumulation in the culture medium, although both iNOS protein and nitrite release were detected in the human pulmonary epithelial cell line A549. 6. Levels of eNOS protein and of NOS mRNA expression were not correlated with gestational stage, suggesting that endogenously produced NO is not likely to be a modulator of myometrial tone during human pregnancy." @default.
• W2034308986 created "2016-06-24" @default.
• W2034308986 creator A5009393702 @default.
• W2034308986 creator A5017842710 @default.
• W2034308986 creator A5019876450 @default.
• W2034308986 creator A5043613761 @default.
• W2034308986 creator A5045203195 @default.
• W2034308986 creator A5064854708 @default.
• W2034308986 creator A5084601957 @default.
• W2034308986 creator A5089847983 @default.
• W2034308986 date "1999-12-01" @default.
• W2034308986 modified "2023-09-24" @default.
• W2034308986 title "Expression of nitric oxide synthase isoforms in pregnant human myometrium" @default.
• W2034308986 cites W1212704 @default.
• W2034308986 cites W1481797092 @default.
• W2034308986 cites W1519147845 @default.
• W2034308986 cites W1596040936 @default.
• W2034308986 cites W1675811512 @default.
• W2034308986 cites W1764308599 @default.
• W2034308986 cites W1929009802 @default.
• W2034308986 cites W1963649699 @default.
• W2034308986 cites W1964136106 @default.
• W2034308986 cites W1966311282 @default.
• W2034308986 cites W1981827248 @default.
• W2034308986 cites W1988358557 @default.
• W2034308986 cites W1990802251 @default.
• W2034308986 cites W1999853564 @default.
• W2034308986 cites W2003354240 @default.
• W2034308986 cites W2007567327 @default.
• W2034308986 cites W2007737411 @default.
• W2034308986 cites W2010592719 @default.
• W2034308986 cites W2010860269 @default.
• W2034308986 cites W2011846765 @default.
• W2034308986 cites W2018289835 @default.
• W2034308986 cites W2019547165 @default.
• W2034308986 cites W2025988440 @default.
• W2034308986 cites W2033979289 @default.
• W2034308986 cites W2040590731 @default.
• W2034308986 cites W2047841570 @default.
• W2034308986 cites W2052638308 @default.
• W2034308986 cites W2052870138 @default.
• W2034308986 cites W2053315032 @default.
• W2034308986 cites W2058410472 @default.
• W2034308986 cites W2060333964 @default.
• W2034308986 cites W2072232293 @default.
• W2034308986 cites W2081642488 @default.
• W2034308986 cites W2094029118 @default.
• W2034308986 cites W2099048452 @default.
• W2034308986 cites W2099426850 @default.
• W2034308986 cites W2100837269 @default.
• W2034308986 cites W2103269080 @default.
• W2034308986 cites W2105779371 @default.
• W2034308986 cites W2115664991 @default.
• W2034308986 cites W2121910079 @default.
• W2034308986 cites W2130987298 @default.
• W2034308986 cites W2135176747 @default.
• W2034308986 cites W2135981710 @default.
• W2034308986 cites W2138676675 @default.
• W2034308986 cites W2148124253 @default.
• W2034308986 cites W2163300609 @default.
• W2034308986 cites W2164319707 @default.
• W2034308986 cites W2169830226 @default.
• W2034308986 cites W2183660367 @default.
• W2034308986 cites W2284294486 @default.
• W2034308986 cites W2416426429 @default.
• W2034308986 doi "https://doi.org/10.1111/j.1469-7793.1999.00705.x" @default.
• W2034308986 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2269695" @default.
• W2034308986 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10601500" @default.
• W2034308986 hasPublicationYear "1999" @default.
• W2034308986 type Work @default.
• W2034308986 sameAs 2034308986 @default.
• W2034308986 citedByCount "31" @default.
• W2034308986 countsByYear W20343089862012 @default.
• W2034308986 countsByYear W20343089862015 @default.
• W2034308986 countsByYear W20343089862017 @default.
• W2034308986 countsByYear W20343089862018 @default.
• W2034308986 countsByYear W20343089862019 @default.
• W2034308986 countsByYear W20343089862023 @default.
• W2034308986 crossrefType "journal-article" @default.
• W2034308986 hasAuthorship W2034308986A5009393702 @default.
• W2034308986 hasAuthorship W2034308986A5017842710 @default.
• W2034308986 hasAuthorship W2034308986A5019876450 @default.
• W2034308986 hasAuthorship W2034308986A5043613761 @default.
• W2034308986 hasAuthorship W2034308986A5045203195 @default.
• W2034308986 hasAuthorship W2034308986A5064854708 @default.
• W2034308986 hasAuthorship W2034308986A5084601957 @default.
• W2034308986 hasAuthorship W2034308986A5089847983 @default.
• W2034308986 hasBestOaLocation W20343089862 @default.
• W2034308986 hasConcept C104317684 @default.
• W2034308986 hasConcept C126322002 @default.
• W2034308986 hasConcept C134018914 @default.
• W2034308986 hasConcept C153911025 @default.
• W2034308986 hasConcept C203014093 @default.
• W2034308986 hasConcept C204232928 @default.
• W2034308986 hasConcept C2777622882 @default.
• W2034308986 hasConcept C2778164554 @default.
• W2034308986 hasConcept C2778326061 @default.
• W2034308986 hasConcept C2779066055 @default.

• next