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- W2034312685 abstract "A method which permits the determination of galactose in the acidic glycosaminoglycans from 50 ml of urine has been developed and evaluated as a measure of the excretion of keratan sulfate-like material. The variation of excretion with age has been determined in normal individuals. The excretion in patients with a variety of pathology has been compared with the data from normals. Excretions significantly higher than normal were found in 8 of 13 patients with Morquio's disease, but only four of these had striking increases. Both patients with GM1 gangliosidosis had grossly elevated excretions. The excretion of all patients with Mucopolysaccharidosis I, II, or III was above normal. The excretion of 2 of 6 patients with achondroplasia, 13 of 30 patients with rheumatoid arthritis, and 4 of 6 patients with dermatomyositis, was also elevated. Occasional values slightly above the normal range were associated with other pathology but in insufficient numbers to establish the significance." @default.
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- W2034312685 date "1972-06-01" @default.
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- W2034312685 title "The determination of galactose in urinary acidic glycosaminoglycans as a measure of keratan sulfate-like substances in urine" @default.
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- W2034312685 doi "https://doi.org/10.1016/0006-2944(72)90045-2" @default.
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