FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034313108> ?p ?o ?g. }

• W2034313108 endingPage "4276" @default.
• W2034313108 startingPage "4267" @default.
• W2034313108 abstract "Two combination dry powder inhalation formulations were engineered via spray drying and co-spray drying salbutamol base (SB) and beclomethasone dipropionate (BDP). The aerosol performances of the individual drugs, a physical mix and the co-spray-dried particle systems were investigated after blending with conventional lactose carrier, under realistic dose regimes. Furthermore, each system was evaluated in terms of the physicochemical properties and via high-throughput Raman microscopy (to study co-association and deposition patterns after in vitro aerosolisation studies). In general, analysis of the aerosol performance (measured using a next-generation impactor) of the single drug and physical mix formulations suggested that SB and BDP have significantly different stage-deposition profiles. Such observations were further substantiated by scanning electron microscopy, where SB–BDP agglomeration could be observed in the physical mix. Stage deposition from the SB–BDP co-spray-dried powders were different than that for the physical mix, wherein the amount of SB and BDP on each stage was equivalent; suggesting that the two drugs could be targeted and deposited at the same location on the lung epithelia. Raman microscopy of the physical mix and co-spray-dried formulations also confirmed the differences in stage deposition between formulations and co-localised deposition for the co-spray-dried formulation. © 2012 Wiley Periodicals, Inc. and the American Pharmacists Association J Pharm Sci 101:4267–4276, 2012" @default.
• W2034313108 created "2016-06-24" @default.
• W2034313108 creator A5004416215 @default.
• W2034313108 creator A5012646235 @default.
• W2034313108 creator A5074685650 @default.
• W2034313108 creator A5087142025 @default.
• W2034313108 date "2012-11-01" @default.
• W2034313108 modified "2023-09-27" @default.
• W2034313108 title "Preparation and Evaluation of Single and Co-Engineered Combination Inhalation Carrier Formulations for the Treatment of Asthma" @default.
• W2034313108 cites W1994629996 @default.
• W2034313108 cites W1998955917 @default.
• W2034313108 cites W2023980894 @default.
• W2034313108 cites W2028637591 @default.
• W2034313108 cites W2031533780 @default.
• W2034313108 cites W2041556535 @default.
• W2034313108 cites W2056301226 @default.
• W2034313108 cites W2064483180 @default.
• W2034313108 cites W2074053180 @default.
• W2034313108 cites W2085766071 @default.
• W2034313108 cites W2088102839 @default.
• W2034313108 cites W2107742493 @default.
• W2034313108 cites W2122148981 @default.
• W2034313108 cites W2127493805 @default.
• W2034313108 cites W2139048430 @default.
• W2034313108 cites W2144902761 @default.
• W2034313108 cites W4248984260 @default.
• W2034313108 doi "https://doi.org/10.1002/jps.23304" @default.
• W2034313108 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22927208" @default.
• W2034313108 hasPublicationYear "2012" @default.
• W2034313108 type Work @default.
• W2034313108 sameAs 2034313108 @default.
• W2034313108 citedByCount "5" @default.
• W2034313108 countsByYear W20343131082013 @default.
• W2034313108 countsByYear W20343131082014 @default.
• W2034313108 countsByYear W20343131082017 @default.
• W2034313108 countsByYear W20343131082019 @default.
• W2034313108 countsByYear W20343131082023 @default.
• W2034313108 crossrefType "journal-article" @default.
• W2034313108 hasAuthorship W2034313108A5004416215 @default.
• W2034313108 hasAuthorship W2034313108A5012646235 @default.
• W2034313108 hasAuthorship W2034313108A5074685650 @default.
• W2034313108 hasAuthorship W2034313108A5087142025 @default.
• W2034313108 hasConcept C105702510 @default.
• W2034313108 hasConcept C111368507 @default.
• W2034313108 hasConcept C120665830 @default.
• W2034313108 hasConcept C121332964 @default.
• W2034313108 hasConcept C127313418 @default.
• W2034313108 hasConcept C127413603 @default.
• W2034313108 hasConcept C136229726 @default.
• W2034313108 hasConcept C151730666 @default.
• W2034313108 hasConcept C159985019 @default.
• W2034313108 hasConcept C178790620 @default.
• W2034313108 hasConcept C185592680 @default.
• W2034313108 hasConcept C192562407 @default.
• W2034313108 hasConcept C26771246 @default.
• W2034313108 hasConcept C2776954882 @default.
• W2034313108 hasConcept C2778517922 @default.
• W2034313108 hasConcept C2778724459 @default.
• W2034313108 hasConcept C2779345167 @default.
• W2034313108 hasConcept C2779587474 @default.
• W2034313108 hasConcept C2816523 @default.
• W2034313108 hasConcept C40003534 @default.
• W2034313108 hasConcept C42360764 @default.
• W2034313108 hasConcept C43617362 @default.
• W2034313108 hasConcept C64297162 @default.
• W2034313108 hasConcept C71924100 @default.
• W2034313108 hasConcept C86803240 @default.
• W2034313108 hasConceptScore W2034313108C105702510 @default.
• W2034313108 hasConceptScore W2034313108C111368507 @default.
• W2034313108 hasConceptScore W2034313108C120665830 @default.
• W2034313108 hasConceptScore W2034313108C121332964 @default.
• W2034313108 hasConceptScore W2034313108C127313418 @default.
• W2034313108 hasConceptScore W2034313108C127413603 @default.
• W2034313108 hasConceptScore W2034313108C136229726 @default.
• W2034313108 hasConceptScore W2034313108C151730666 @default.
• W2034313108 hasConceptScore W2034313108C159985019 @default.
• W2034313108 hasConceptScore W2034313108C178790620 @default.
• W2034313108 hasConceptScore W2034313108C185592680 @default.
• W2034313108 hasConceptScore W2034313108C192562407 @default.
• W2034313108 hasConceptScore W2034313108C26771246 @default.
• W2034313108 hasConceptScore W2034313108C2776954882 @default.
• W2034313108 hasConceptScore W2034313108C2778517922 @default.
• W2034313108 hasConceptScore W2034313108C2778724459 @default.
• W2034313108 hasConceptScore W2034313108C2779345167 @default.
• W2034313108 hasConceptScore W2034313108C2779587474 @default.
• W2034313108 hasConceptScore W2034313108C2816523 @default.
• W2034313108 hasConceptScore W2034313108C40003534 @default.
• W2034313108 hasConceptScore W2034313108C42360764 @default.
• W2034313108 hasConceptScore W2034313108C43617362 @default.
• W2034313108 hasConceptScore W2034313108C64297162 @default.
• W2034313108 hasConceptScore W2034313108C71924100 @default.
• W2034313108 hasConceptScore W2034313108C86803240 @default.
• W2034313108 hasIssue "11" @default.
• W2034313108 hasLocation W20343131081 @default.
• W2034313108 hasLocation W20343131082 @default.
• W2034313108 hasOpenAccess W2034313108 @default.
• W2034313108 hasPrimaryLocation W20343131081 @default.
• W2034313108 hasRelatedWork W2009690969 @default.

• next