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• W2034320273 abstract "Purpose/Objective(s)Examine the feasibility of incorporating a dual energy subtraction technique to enhance and improve target localization for thoracic radiotherapy treatment.Materials/MethodsModern linear accelerators now include kilovoltage on-board imagers (OBI) to aid in target localization. These systems are being used to generate daily cone beam CTs (CBCT) to determine if the target volume is properly positioned for treatment; however, radiation dose and time delays may be a problem over the course of a multiple week treatment. CBCT scans are needed to adequately determine the target lesion location in the thorax because conventional 2D x-ray images have poor soft tissue visualization due to anatomical superposition of soft tissue and complicated bony anatomy (mainly ribs). Additionally, CBCT images are known to have decreased visualization and poor delineation of target volumes due to breathing motion artifact blur caused by long acquisition times.Dual-energy (DE) subtraction imaging is a mathematical technique used to separate an image into tissue-only and bone-only images using two rapidly acquired x-ray images with different energy spectra. DE tissue-only images allow for the removal of overlying bony structure and will provide substantially enhanced visibility of soft tissue anatomy, including lung lesions, for external-beam radiotherapy targeting.For this study, 3 simple objects were placed on the chest of an anthropomorphic phantom to simulate lung nodules and 2 x-ray images (120 and 70 kVp) were acquired using an OBI on a 21ix Clinac. The DE subtraction technique was performed to generate a tissue-only image, which was assessed for improved visibility of the embedded nodules due to the removal of the ribs in the lung region.ResultsThe included Figure shows the high energy, low energy, and tissue-only DE images. The 3 simulated nodules are clearly more visible in the DE subtraction image. Note the excellent subtraction of the entirety of the bony ribs in the chest region.Conclusions Purpose/Objective(s)Examine the feasibility of incorporating a dual energy subtraction technique to enhance and improve target localization for thoracic radiotherapy treatment. Examine the feasibility of incorporating a dual energy subtraction technique to enhance and improve target localization for thoracic radiotherapy treatment. Materials/MethodsModern linear accelerators now include kilovoltage on-board imagers (OBI) to aid in target localization. These systems are being used to generate daily cone beam CTs (CBCT) to determine if the target volume is properly positioned for treatment; however, radiation dose and time delays may be a problem over the course of a multiple week treatment. CBCT scans are needed to adequately determine the target lesion location in the thorax because conventional 2D x-ray images have poor soft tissue visualization due to anatomical superposition of soft tissue and complicated bony anatomy (mainly ribs). Additionally, CBCT images are known to have decreased visualization and poor delineation of target volumes due to breathing motion artifact blur caused by long acquisition times.Dual-energy (DE) subtraction imaging is a mathematical technique used to separate an image into tissue-only and bone-only images using two rapidly acquired x-ray images with different energy spectra. DE tissue-only images allow for the removal of overlying bony structure and will provide substantially enhanced visibility of soft tissue anatomy, including lung lesions, for external-beam radiotherapy targeting.For this study, 3 simple objects were placed on the chest of an anthropomorphic phantom to simulate lung nodules and 2 x-ray images (120 and 70 kVp) were acquired using an OBI on a 21ix Clinac. The DE subtraction technique was performed to generate a tissue-only image, which was assessed for improved visibility of the embedded nodules due to the removal of the ribs in the lung region. Modern linear accelerators now include kilovoltage on-board imagers (OBI) to aid in target localization. These systems are being used to generate daily cone beam CTs (CBCT) to determine if the target volume is properly positioned for treatment; however, radiation dose and time delays may be a problem over the course of a multiple week treatment. CBCT scans are needed to adequately determine the target lesion location in the thorax because conventional 2D x-ray images have poor soft tissue visualization due to anatomical superposition of soft tissue and complicated bony anatomy (mainly ribs). Additionally, CBCT images are known to have decreased visualization and poor delineation of target volumes due to breathing motion artifact blur caused by long acquisition times. Dual-energy (DE) subtraction imaging is a mathematical technique used to separate an image into tissue-only and bone-only images using two rapidly acquired x-ray images with different energy spectra. DE tissue-only images allow for the removal of overlying bony structure and will provide substantially enhanced visibility of soft tissue anatomy, including lung lesions, for external-beam radiotherapy targeting. For this study, 3 simple objects were placed on the chest of an anthropomorphic phantom to simulate lung nodules and 2 x-ray images (120 and 70 kVp) were acquired using an OBI on a 21ix Clinac. The DE subtraction technique was performed to generate a tissue-only image, which was assessed for improved visibility of the embedded nodules due to the removal of the ribs in the lung region. ResultsThe included Figure shows the high energy, low energy, and tissue-only DE images. The 3 simulated nodules are clearly more visible in the DE subtraction image. Note the excellent subtraction of the entirety of the bony ribs in the chest region. The included Figure shows the high energy, low energy, and tissue-only DE images. The 3 simulated nodules are clearly more visible in the DE subtraction image. Note the excellent subtraction of the entirety of the bony ribs in the chest region. Conclusions" @default.
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• W2034320273 title "A Preliminary Investigation of Dual Energy Subtraction Imaging for Improved Target Localization in the Thorax" @default.
• W2034320273 doi "https://doi.org/10.1016/j.ijrobp.2007.07.1701" @default.
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